scholarly journals Modifications of bacterial cellulose in wound care

2021 ◽  
Vol 51 (2) ◽  
pp. 0-0
Author(s):  
Ruth Dudek-Wicher ◽  
Justyna Paleczny ◽  
Malwina Brożyna ◽  
Adam Junka ◽  
Marzenna Bartoszewicz
Keyword(s):  
Bacterial Cellulose ◽  
Wound Care

scholarly journals Curcumin-Loaded Bacterial Cellulose/Alginate/Gelatin as A Multifunctional Biopolymer Composite Film

Molecules ◽  
2020 ◽  
Vol 25 (17) ◽  
pp. 3800 ◽  
Author(s):  
Nadda Chiaoprakobkij ◽  
Thapanar Suwanmajo ◽  
Neeracha Sanchavanakit ◽  
Muenduen Phisalaphong
Keyword(s):  
Oral Cancer ◽  
Bacterial Cellulose ◽  
Wound Care ◽  
Artificial Saliva ◽  
Water Vapor Permeability ◽  
Contact Angles ◽  
Vapor Permeability ◽  
Sem Images ◽  
Water Contact

Multifunctional biopolymer composites comprising mechanically-disintegrated bacterial cellulose, alginate, gelatin and curcumin plasticized with glycerol were successfully fabricated through a simple, facile, cost-effective mechanical blending and casting method. SEM images indicate a well-distributed structure of the composites. The water contact angles existed in the range of 50–70°. Measured water vapor permeability values were 300–800 g/m2/24 h, which were comparable with those of commercial dressing products. No release of curcumin from the films was observed during the immersion in PBS and artificial saliva, and the fluid uptakes were in the range of 100–700%. Films were stretchable and provided appropriate stiffness and enduring deformation. Hydrated films adhered firmly onto the skin. In vitro mucoadhesion time was found in the range of 0.5–6 h with porcine mucosa as model membrane under artificial saliva medium. The curcumin-loaded films had substantial antibacterial activity against E. coli and S. aureus. The films showed non-cytotoxicity to human keratinocytes and human gingival fibroblasts but exhibited potent anticancer activity in oral cancer cells. Therefore, these curcumin-loaded films showed their potential for use as leave-on skin applications. These versatile films can be further developed to achieve desirable characteristics for local topical patches for wound care, periodontitis and oral cancer treatment.

Bacterial Nanocellulose for Medicine Regenerative

2011 ◽  
Vol 2 (3) ◽  
Author(s):  
Gabriel Molina de Olyveira ◽  
Ligia Maria Manzine Costa ◽  
Pierre Basmaji ◽  
Lauro Xavier Filho
Keyword(s):  
Bacterial Cellulose ◽  
Wound Care ◽  
Glass Fibers ◽  
Natural Fibers ◽  
Cell Immobilization ◽  
Average Diameter ◽  
Degree Of Polymerization ◽  
Cellulose Membrane ◽  
Cellulose Modification ◽  
Pure Cellulose

Bacterial cellulose (BC) has established to be a remarkably versatile biomaterial and can be used in a wide variety of applied scientific endeavours, especially for medical devices. Nanocellulose, such as that produced by the bacteria Gluconacetobacter xylinus (bacterial cellulose, BC), is an emerging biomaterial with great potential in flexible radar absorbing materials, in scaffold for tissue regeneration, water treatment, and medical applications. Bacterial cellulose nanofibril bundles have excellent intrinsic properties due to their high crystallinity, which is higher than that generally recorded for macroscale natural fibers and is of the same order as the elastic modulus of glass fibers. Compared with cellulose from plants, BC also possesses higher water holding capacity, higher degree of polymerization (up to 8000), and a finer weblike network. In addition, BC is produced as a highly hydrated and relatively pure cellulose membrane, and therefore no chemical treatments are needed to remove lignin and hemicelluloses, as is the case for plant cellulose. Because of these characteristics, biomedical devices recently have gained a significant amount of attention because of an increased interest in tissue-engineered products for both wound care and the regeneration of damaged or diseased organs. Hydrophilic bacterial cellulose fibers of an average diameter of 50 nm are produced by the bacterium Acetobacter xylinum, using a fermentation process. The architecture of BC materials can be engineered over length scales ranging from nano to macro by controlling the biofabrication process. Moreover, the nanostructure and morphological similarities with collagen make BC attractive for cell immobilization and cell support. This review describes the fundamentals, purification, and morphological investigation of bacterial cellulose. Besides, microbial cellulose modification and how to increase the compatibility between cellulosic surfaces and a variety of plastic materials have been reported. Furthermore, provides deep knowledge of current and future applications of bacterial cellulose and their nanocomposites especially in the medical field.

Take Your Pick of Multiple Wound-Care Dressings

2005 ◽  
Vol 38 (1) ◽  
pp. 26
Author(s):  
ROBERT FINN
Keyword(s):  
Wound Care

VR for adjunctive analgesia during burn wound care and physical therapy

1999 ◽  
Author(s):  
Hunter G. Hoffman ◽  
David R. Patterson ◽  
Gretchen J. Carrougher ◽  
Thomas A. Furness
Keyword(s):  
Physical Therapy ◽  
Wound Care ◽  
Burn Wound

Healing venous ulcers with different modalities of leg compression

Phlebologie ◽  
2006 ◽  
Vol 35 (05) ◽  
pp. 349-355 ◽  
Author(s):  
E. O. Brizzio ◽  
G. Rossi ◽  
A. Chirinos ◽  
I. Cantero ◽  
G. Idiazabal ◽  
...  
Keyword(s):  
Wound Care ◽  
Univariate Analysis ◽  
Compression Therapy ◽  
Healing Time ◽  
Clinical Parameters ◽  
Compression Stockings ◽  
Local Pressure ◽  
Ulcer Size ◽  
Venous Ulcers ◽  
Unexpected Findings

Summary Background: Compression therapy (CT) is the stronghold of treatment of venous leg ulcers. We evaluated 5 modalities of CT in a prospective open pilot study using a unique trial design. Patients and methods: A group of experienced phlebologists assigned 31 consecutive patients with 35 venous ulcers (present for 2 to 24 months with no prior CT) to 5 different modalities of leg compression, 7 ulcers to each group. The challenge was to match the modality of CT with the features of the ulcer in order to achieve as many healings as possible. Wound care used standard techniques and specifically tailored foam pads to increase local pressure. CT modalities were either stockings Sigvaris® 15-20, 20-30, 30-40 mmHg, multi-layer bandages, or CircAid® bandaging. Compression was maintained day and night in all groups and changed at weekly visits. Study endpoints were time to healing and the clinical parameters predicting the outcome. Results: The cumulative healing rates were 71%, 77%, and 83% after 3, 6, and 9 months, respectively. Univariate analysis of variables associated with nonhealing were: previous surgery, presence of insufficient perforating and/or deep veins, older age, recurrence, amount of oedema, time of presence of CVI and the actual ulcer, and ulcer size (p <0.05-<0.001). The initial ulcer size was the best predictor of the healing-time (Pearson r=0.55, p=0.002). The modality of CT played an important role also, as 19 of 21 ulcers (90%) healed with stockings but only 8 of 14 with bandages (57%; p=0.021). Regression analysis allowed to calculate a model to predict the healing time. It compensated for the fact that patients treated with low or moderate compression stockings were at lower risk of non-healing. and revealed that healing with stockings was about twice as rapid as healing with bandages. Conclusion: Three fourths of venous ulcers can be brought to healing within 3 to 6 months. Healing time can be predicted using easy to assess clinical parameters. Irrespective of the initial presentation ulcer healing appeared more rapid with the application of stockings than with bandaging. These unexpected findings contradict current believes and require confirmation in randomised trials.

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