scholarly journals Curcumin-Loaded Bacterial Cellulose/Alginate/Gelatin as A Multifunctional Biopolymer Composite Film

Molecules ◽  
2020 ◽  
Vol 25 (17) ◽  
pp. 3800 ◽  
Author(s):  
Nadda Chiaoprakobkij ◽  
Thapanar Suwanmajo ◽  
Neeracha Sanchavanakit ◽  
Muenduen Phisalaphong
Keyword(s):  
Oral Cancer ◽  
Bacterial Cellulose ◽  
Wound Care ◽  
Artificial Saliva ◽  
Water Vapor Permeability ◽  
Contact Angles ◽  
Vapor Permeability ◽  
Sem Images ◽  
Water Contact

Multifunctional biopolymer composites comprising mechanically-disintegrated bacterial cellulose, alginate, gelatin and curcumin plasticized with glycerol were successfully fabricated through a simple, facile, cost-effective mechanical blending and casting method. SEM images indicate a well-distributed structure of the composites. The water contact angles existed in the range of 50–70°. Measured water vapor permeability values were 300–800 g/m2/24 h, which were comparable with those of commercial dressing products. No release of curcumin from the films was observed during the immersion in PBS and artificial saliva, and the fluid uptakes were in the range of 100–700%. Films were stretchable and provided appropriate stiffness and enduring deformation. Hydrated films adhered firmly onto the skin. In vitro mucoadhesion time was found in the range of 0.5–6 h with porcine mucosa as model membrane under artificial saliva medium. The curcumin-loaded films had substantial antibacterial activity against E. coli and S. aureus. The films showed non-cytotoxicity to human keratinocytes and human gingival fibroblasts but exhibited potent anticancer activity in oral cancer cells. Therefore, these curcumin-loaded films showed their potential for use as leave-on skin applications. These versatile films can be further developed to achieve desirable characteristics for local topical patches for wound care, periodontitis and oral cancer treatment.

scholarly journals Upcycling of Vine Shoots: Production of Fillers for PHBV-Based Biocomposite Applications

2020 ◽  
Author(s):  
Grégoire David ◽  
Laurent Heux ◽  
Stéphanie Pradeau ◽  
Nathalie Gontard ◽  
Hélène Angellier-Coussy
Keyword(s):  
Water Vapor ◽  
Gas Phase ◽  
Mechanical Performance ◽  
Low Cost ◽  
Water Vapor Permeability ◽  
Contact Angles ◽  
Vapor Permeability ◽  
Water Contact ◽  
Median Diameter ◽  
Cost Of Materials

Abstract This paper aims at investigating the potential of vine shoots (ViSh) upcycling as fillers in novel poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) based biocomposites. ViSh particles of around 50 µm (apparent median diameter) were obtained combining dry grinding processes, and mixed with PHBV using melt extrusion. Thermal stability and elongation at break of biocomposites were reduced with increasing contents of ViSh particles (10, 20 and 30 wt%), while Young’s modulus and water vapor permeability were increased. It was shown that a surface gas-phase esterification allowed to significantly increase the hydrophobicity of ViSh particles (increase of water contact angles from 59° to 114°), leading to a reduction of 27% in the water vapor permeability of the biocomposite filled with 30 wt% of ViSh. The overall mechanical performance was not impacted by gas-phase esterification, demonstrating that the interfacial adhesion between the virgin ViSh particles and the PHBV matrix was already good and that such filler surface treatment was not required in that case. It was concluded that ViSh particles can be interestingly used as low cost fillers in PHBV-based biocomposites to decrease the overall cost of materials.

scholarly journals Preparation and Properties of Corn Starch/Chitin Composite Films Cross-Linked by Maleic Anhydride

Polymers ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1606
Author(s):  
Peng Yin ◽  
Jinglong Liu ◽  
Wen Zhou ◽  
Panxin Li
Keyword(s):  
Maleic Anhydride ◽  
Corn Starch ◽  
Composite Films ◽  
Water Vapor Permeability ◽  
Contact Angles ◽  
Vapor Permeability ◽  
Water Contact ◽  
Elongation At Break ◽  
Shrimp Shell ◽  
Starch Films

To improve the functional properties of starch-based films, chitin (CH) was prepared from shrimp shell powder and incorporated into corn starch (CS) matrix. Before blending, maleic anhydride (MA) was introduced as a cross-linker. Composite CS/MA-CH films were obtained by casting-evaporation approach. Mechanical property estimation showed that addition of 0–7 wt % MA-CH improved the tensile strength of starch films from 3.89 MPa to 9.32 MPa. Elongation at break of the films decreased with the addition of MA-CH, but the decrease was obviously reduced than previous studies. Morphology analysis revealed that MA-CH homogeneously dispersed in starch matrix and no cracks were found in the CS/MA-CH films. Incorporation of MA-CH decreased the water vapor permeability of starch films. The water uptake of the films was reduced when the dosage of MA-CH was below 5 wt %. Water contact angles of the starch films increased from 22° to 86° with 9 wt % MA-CH incorporation. Besides, the composite films showed better inhibition effect against Escherichia coli and Staphylococcus aureus than pure starch films.

scholarly journals Surface Modification of Poly(lactic-co-glycolic acid) Microspheres with Enhanced Hydrophilicity and Dispersibility for Arterial Embolization

Materials ◽  
2019 ◽  
Vol 12 (12) ◽  
pp. 1959
Author(s):  
Jiao Wang ◽  
Jianbo Li ◽  
Jie Ren
Keyword(s):  
Glycolic Acid ◽  
Arterial Embolization ◽  
Contact Angles ◽  
In Vitro Cytotoxicity ◽  
Plga Microspheres ◽  
Sem Images ◽  
Water Contact ◽  
Prospective Application ◽  
Ft Ir

In this study, a series of poly(lactic-co-glycolic acid) (PLGA) microspheres with different particle sizes for arterial embolization surgery were prepared. The polydopamine (PDA) and polydopamine/polyethyleneimine (PDA/PEI) were respectively coated on the PLGA microspheres as shells, in order to improve the hydrophilicity and dispersibility of PLGA embolization microspheres. After modification, with the introduction of PDA and PEI, many hydrophilic hydroxyl and amine groups appeared on the surface of the PLGA@PDA and PLGA@PDA/PEI microspheres. SEM images showed the morphologies, sizes, and changes of the as-prepared microspheres. Meanwhile, the XPS and FT-IR spectra demonstrated the successful modification of the PDA and PEI. Water contact angles (WCAs) of the PLGA@PDA and PLGA@PDA/PEI microspheres became smaller, indicating a certain improvement in surface hydrophilicity. In addition, the results of in vitro cytotoxicity showed that modification had little effect on the biosafety of the microspheres. The modified PLGA microspheres suggest a promising prospective application in biomedical field, as the modified microspheres can reduce difficulties in embolization surgery.

Effect of DMDHEU treatment on properties of bacterial cellulose material

2021 ◽  
pp. 004051752199235
Author(s):  
Florentina Sederavičiūtė ◽  
Jurgita Domskienė ◽  
Lina Jurgelionytė ◽  
Audronė Sankauskaite ◽  
Dushan Kimmer
Keyword(s):  
Water Absorption ◽  
Bacterial Cellulose ◽  
Three Dimensional ◽  
Water Vapor Permeability ◽  
Barrier Properties ◽  
Absorption Capacity ◽  
Vapor Permeability ◽  
Crosslinking Reaction ◽  
Sem Images ◽  
Cellulose Material

The aim of this study was to estimate the influence of purification and treatment with textile finishing agent procedures on structural, mechanical, and water barrier properties of bacterial cellulose (BC) in order to predict the end-use properties. Kombucha fungus generated by Komagataeibacter xylinus species, formerly known as Gluconacetobacter xylinus, was used to produce the BC material. The BC was purified with 0.5% sodium hydroxide (NaOH) solution and treated with 5%, 10%, and 20% concentration of N, N-dimethylol 4,5-dihydroxy-ethylene urea (DMDHEU). By Fourier transform spectroscopy (FTIR) and X-ray diffractometer (XRD) was estimated, that the purification with a weak alkali solution was effective to remove amorphous matter of the BC material. Scanning electron microscope (SEM) images demonstrated the BC structure, similar to a non-woven textile fabric with clearly visible three-dimensional networks of fine cellulose fibers. After the purification process, the BC material tensile strength increased by 52%; however, the strain decreased by 93%. BC material after treatment with 20% DMDHEU regained deformability and tensile properties analogous to untreated samples. Water vapor permeability (WVP) values increased and water absorption capacity (WAC) decreased in BC material with increasing DMDHEU concentration. According to the FTIR results, the crosslinking reaction of DMDHEU and adjacent BC molecules was proved. The treatment with DMDHEU restores the amorphous properties of BC material, and therefore blocks water absorption, and the decrease in the water absorption parameter might be determined.

Surface Properties of Superhydrophobic Coatings for Stone Protection

2009 ◽  
Vol 8 ◽  
pp. 23-33 ◽  
Author(s):  
P.N. Manoudis ◽  
I. Karapanagiotis ◽  
A. Tsakalof ◽  
I. Zuburtikudis ◽  
B. Kolinkeová ◽  
...  
Keyword(s):  
Contact Angle ◽  
Water Vapor Permeability ◽  
Sio2 Nanoparticles ◽  
Vapor Permeability ◽  
Capillary Absorption ◽  
Sem Images ◽  
Water Contact ◽  
Static Contact ◽  
Colorimetric Measurements ◽  
Glass Surfaces

Superhydrophobic films are produced by a simple and low cost method. Silica (SiO2) nanoparticles are dispersed in solutions of Rhodorsil 224, a commercial poly(alkyl siloxane) which is used for the protection of outdoor cultural heritage objects, and the suspensions are sprayed on glass surfaces. It is shown that the siloxane-nanoparticle composite films prepared from dispersions of high particle concentrations (≥ 0.5% w/v) exhibit superydrophobic properties (high static contact angle and small hysteresis) which can be rationalized by the Cassie-Baxter model, according to quantitative measurements obtained by SEM images. Siloxane-nanoparticle films are then deposited (sprayed) on “Opuka”, a fine-grained argillite which was used for the restoration of the castle of Prague. It is shown that the treated stone surfaces exhibit superydrophobic properties, similar to the treated glass surfaces. The efficacy of the superhydrophobic films to protect Opuka is evaluated by performing water contact angle, water capillary absorption, water vapor permeability and colorimetric measurements. It is shown that the use of nanoparticles in the protective coating has a positive effect on the results of the aforementioned tests, except for the colorimetric measurements.

scholarly journals Enzymatic and Chemical Cross-Linking of Bacterial Cellulose/Fish Collagen Composites—A Comparative Study

2021 ◽  
Vol 22 (7) ◽  
pp. 3346
Author(s):  
Agata Sommer ◽  
Paulina Dederko-Kantowicz ◽  
Hanna Staroszczyk ◽  
Sławomir Sommer ◽  
Marek Michalec
Keyword(s):  
Thermal Stability ◽  
Bacterial Cellulose ◽  
Secondary Alcohol ◽  
Water Vapor Permeability ◽  
Polymer Chains ◽  
Cross Linking ◽  
Vapor Permeability ◽  
Covalent Bonds ◽  
Fish Collagen ◽  
Chemical Cross Linking

This article compares the properties of bacterial cellulose/fish collagen composites (BC/Col) after enzymatic and chemical cross-linking. In our methodology, two transglutaminases are used for enzymatic cross-linking—one recommended for the meat and the other proposed for the fish industry—and pre-oxidated BC (oxBC) is used for chemical cross-linking. The structure of the obtained composites is characterized by scanning electron microscopy, thermogravimetric analysis, X-ray diffraction, and Fourier transform infrared spectroscopy, and their functional properties by mechanical and water barrier tests. While polymer chains in uncross-linked BC/Col are intertwined by H-bonds, new covalent bonds in enzymatically cross-linked ones are formed—resulting in increased thermal stability and crystallinity of the material. The C2–C3 bonds cleavage in D-glucose units, due to BC oxidation, cause secondary alcohol groups to vanish in favor of the carbonyl groups’ formation, thus reducing the number of H-bonded OHs. Thermal stability and crystallinity of oxBC/Col remain lower than those of BC/Col. The BC/Col formation did not affect tensile strength and water vapor permeability of BC, but enzymatic cross-linking with TGGS improved them significantly.

scholarly journals Fast Dissolving Electrospun Nanofibers Fabricated from Jelly Fig Polysaccharide/Pullulan for Drug Delivery Applications

Polymers ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 241
Author(s):  
Thangavel Ponrasu ◽  
Bei-Hsin Chen ◽  
Tzung-Han Chou ◽  
Jia-Jiuan Wu ◽  
Yu-Shen Cheng
Keyword(s):  
Drug Delivery ◽  
Water Vapor Permeability ◽  
Electrospun Nanofibers ◽  
Average Diameter ◽  
Xrd Analysis ◽  
Water Soluble ◽  
Vapor Permeability ◽  
Uv Spectrum ◽  
Sem Images ◽  
Triton X

The fast-dissolving drug delivery systems (FDDDSs) are developed as nanofibers using food-grade water-soluble hydrophilic biopolymers that can disintegrate fast in the oral cavity and deliver drugs. Jelly fig polysaccharide (JFP) and pullulan were blended to prepare fast-dissolving nanofiber by electrospinning. The continuous and uniform nanofibers were produced from the solution of 1% (w/w) JFP, 12% (w/w) pullulan, and 1 wt% Triton X-305. The SEM images confirmed that the prepared nanofibers exhibited uniform morphology with an average diameter of 144 ± 19 nm. The inclusion of JFP in pullulan was confirmed by TGA and FTIR studies. XRD analysis revealed that the increased crystallinity of JFP/pullulan nanofiber was observed due to the formation of intermolecular hydrogen bonds. The tensile strength and water vapor permeability of the JFP/pullulan nanofiber membrane were also enhanced considerably compared to pullulan nanofiber. The JFP/pullulan nanofibers loaded with hydrophobic model drugs like ampicillin and dexamethasone were rapidly dissolved in water within 60 s and release the encapsulants dispersive into the surrounding. The antibacterial activity, fast disintegration properties of the JFP/pullulan nanofiber were also confirmed by the zone of inhibition and UV spectrum studies. Hence, JFP/pullulan nanofibers could be a promising carrier to encapsulate hydrophobic drugs for fast-dissolving/disintegrating delivery applications.

scholarly journals Incorporation of Lipids into Wheat Bran Cellulose/Wheat Gluten Composite Film Improves Its Water Resistance Properties

Membranes ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 18
Author(s):  
Guanghui Shen ◽  
Guoxian Yu ◽  
Hejun Wu ◽  
Shanshan Li ◽  
Xiaoyan Hou ◽  
...  
Keyword(s):  
Composite Film ◽  
Wheat Bran ◽  
Food Packaging ◽  
Water Resistance ◽  
Wheat Gluten ◽  
Vapor Permeability ◽  
Scanning Calorimetry ◽  
Sem Images ◽  
Water Contact ◽  
Cross Sectional

This work evaluated the improvement effects of lipids incorporation on water resistance of composite biodegradable film prepared with wheat bran cellulose/wheat gluten (WBC/WG) using an alkaline–ethanol film forming system. Four types of lipids, paraffin wax (PW), beeswax (BW), paraffin oil (PO), and oleic acid (OA), were tested. We found that PW, BW, and PO incorporation at 5–20% improved water vapor permeability (WVP) and surface hydrophobicity of prepared films. Particularly, incorporation of 15% BW could best improve the water resistance properties of the film, with the lowest WVP of 0.76 × 10−12 g/cm·s·Pa and largest water contact angle (WCA) of 86.18°. Incorporation of OA led to the decline in moisture barrier properties. SEM images revealed that different lipids incorporation changed the morphology and of the composite film, and cross-sectional morphology indicated BW-incorporated film obtained more uniform and compact structures compared to other films. Moreover, Fourier transform infrared spectra indicated that the incorporation of PW or BW enhanced the molecular interactions between the film components, confirmed by the chemical shift of characteristic peaks at 3277 and 1026 cm−1. Differential scanning calorimetry results revealed that incorporation of PW, BW, and PO increased films’ melting point, decomposition temperatures, and enthalpy values. Furthermore, the presence of most lipids decreased tensile strength and elongation at the break of the film. Overall, the composite film containing 15% BW obtained the most promising water resistance performance and acceptable mechanical properties, and it thus most suitable as a hydrophobic biodegradable material for food packaging.

Surface Modification of PEOT/PBT Membrane with Silk Fibroin Anchoring and its Potential Application in Artificial Salivary Gland Construct

2012 ◽  
Vol 538-541 ◽  
pp. 52-59
Author(s):  
Jie Zhu ◽  
Ming Shi Li ◽  
Li Qun Wang ◽  
Xiao Lin Zhu
Keyword(s):  
Salivary Gland ◽  
Silk Fibroin ◽  
Potential Application ◽  
Contact Angles ◽  
Water Contact ◽  
Polar Groups ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene ◽  
Surface Modified

We reported the preparation of surface modified poly (ethylene oxide terephthalate) - poly (butylene terephthalate) membrane by the method of silk fibroin anchoring, namely SF/(PEOT/PBT). Its surface properties were characterized by contact angles and XPS and the biocompatibility of the composite membrane was further evaluated by human salivary epithelial cells (HSG cells) growth in vitro. Results revealed that SF/(PEOT/PBT) possessed the low water contact angle (48.0±3.0°) and immobilized a great amount of fibroin (fibroin surface coverage: 26.39 wt%), which attributed to the formation of polar groups such as hydrosulfide group, sulfonic group, carboxyl and carbonyl ones in the process of SO2 plasma treatment. HSG cells growth in vitro indicated that the silk fibroin anchoring could significantly enhance the biocompatibility of PEOT/PBT membrane, which suggested the potential application of fibroin anchoring PEOT/PBT for clinical HSG cells transplantation in the artificial salivary gland construct.

scholarly journals Scaffolds for Wound Healing Applications

Polymers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2010 ◽  
Author(s):  
Irina Negut ◽  
Gabriela Dorcioman ◽  
Valentina Grumezescu
Keyword(s):  
Wound Healing ◽  
Wound Care ◽  
Water Vapor Permeability ◽  
Cellular Migration ◽  
Wound Dressings ◽  
Vapor Permeability ◽  
Therapeutic Effects ◽  
Microbial Invasion ◽  
Polymeric Biomaterials ◽  
Hybrid Biomaterials

In order to overcome the shortcomings related to unspecific and partially efficient conventional wound dressings, impressive efforts are oriented in the development and evaluation of new and effective platforms for wound healing applications. In situ formed wound dressings provide several advantages, including proper adaptability for wound bed microstructure and architecture, facile application, patient compliance and enhanced therapeutic effects. Natural or synthetic, composite or hybrid biomaterials represent suitable candidates for accelerated wound healing, by providing proper air and water vapor permeability, structure for macro- and microcirculation, support for cellular migration and proliferation, protection against microbial invasion and external contamination. Besides being the most promising choice for wound care applications, polymeric biomaterials (either from natural or synthetic sources) may exhibit intrinsic wound healing properties. Several nanotechnology-derived biomaterials proved great potential for wound healing applications, including micro- and nanoparticulate systems, fibrous scaffolds, and hydrogels. The present paper comprises the most recent data on modern and performant strategies for effective wound healing.

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