Canine histiocytic syndrome manifested as ulcerative gastroenterocolitis, skin lesions and lymphadenopathy &ndash; a case report

Histiocytic syndrome was diagnosed in a 7-year-old boxer bitch using histological and immunohistochemical methods. Necropsy confirmed the presence of enlarged superficial lymph nodes, two large ulcerated oval cutaneous masses one on the left lateral thoracic wall and one near to the vulva. In the gastrointestinal tract there were multiple ulcers apparently overlying nodules located in the submucosa of stomach, ulcers in the ileocaecal valve, and enlargement of lymphoid nodules in the small intestine manifested ulcerative gastroenteritis. Histologically, the thoracic wall mass showed infiltration of the tissue by macrophages with cytoplasmic vacuoles. The vacuoles contained PAS-positive polysaccharides. The macrophages were positive for alpha-1-antitrypsin and lysozyme by immunostaining. Lysozyme is a marker for phagocytic macrophages/histiocytes and may be used to confirm cells of this lineage in cases when there is any doubt.

Download Full-text

A SPECIFIC INFECTION CHARACTERIZED BY MULTIPLE ULCERS OF THE SMALL INTESTINE

Archives of Internal Medicine ◽

10.1001/archinte.1936.00170160024002 ◽

1936 ◽

Vol 58 (6) ◽

pp. 978

Author(s):

LELAND M. JOHNSTON

Keyword(s):

Small Intestine ◽

Multiple Ulcers

Download Full-text

Multiple Small Intestine Ulcers with Desquamation of the Fingers

Case Reports in Gastroenterology ◽

10.1159/000479222 ◽

2017 ◽

Vol 11 (2) ◽

pp. 452-461

Author(s):

Azusa Kawasaki ◽

Kunihiro Tsuji ◽

Hisashi Doyama

Keyword(s):

Computed Tomography ◽

Small Intestine ◽

Abdominal Pain ◽

Small Bowel ◽

Yersinia Pseudotuberculosis ◽

Oral Ulcers ◽

Palmar Erythema ◽

Antibody Titers ◽

Endoscopic Characteristics ◽

Multiple Ulcers

A 73-year-old female was admitted to our hospital with abdominal pain and diarrhea. Computed tomography detected distension of the small intestine. A palmar erythema, multiple oral ulcers, and desquamation of the fingers appeared after hospitalization. Small-bowel endoscopic images showed multiple ulcers. We attributed this case to infection with Yersinia pseudotuberculosis based on the changes in Y. pseudotuberculosis antibody titers throughout the course of the illness. This report is valuable, as it illustrates the endoscopic characteristics of a Y. pseudotuberculosis infection with skin lesion and ileus, which may enable us to deepen the pathologic understanding of this disease.

Download Full-text

META-ANALYSIS ON ETIOPATHOGENESIS OF SMALL BOWEL OBSTRUCTION IN THE DEPARTMENT OF GEN. SURGERY P.M.C.H. & K.M.C.H., BIHAR

10.36106/ijsr/6700138 ◽

2021 ◽

pp. 1-3

Author(s):

Abhishek Chaudhary ◽

Kanchan Sone Lal Baitha ◽

Yasir Tajdar

Keyword(s):

Small Intestine ◽

Small Bowel ◽

Abdominal Surgery ◽

Intestinal Obstruction ◽

Small Bowel Obstruction ◽

Bowel Obstruction ◽

Meta Analysis ◽

Ileocaecal Valve ◽

Time Period ◽

Ligament Of Treitz

Background:The small intestine is the longest and convoluted portion in the digestive tract. It starts from pylorus and ends at ileocaecal valve. The small bowel consists of three parts measuring about 5 to 6 meters. The rst 25cm is the duodenum. Out of the rest part of small gut, jejunum th th. constitute the proximal 2/5 and ileum distal 3/5 The jejunum and ileum extend from the peritoneal fold that supports the duodeno-jejunal junction (Ligament of Treitz) down to ileocaecal valve. Material and Methods:All the patients admitted to PMCH, Patna and KMC, Katihar as intestinal obstruction was included for the study. The time period of study was from October 2014 to November 2016 in PMCH and December 2016 to January 2019 in KMC, Katihar. Out of all Intestinal obstruction 59 cases only of adult small gut obstruction were recorded for comparison and conclusive study.Conclusion: Small bowel obstruction remains a frequently encountered problem in abdominal surgery. Although modern day surgical management continues to focus appropriately on avoiding delayed operation, whatever surgery is indicated, not every patient is always best served by immediate operation

Download Full-text

Uptake of Ferritin by Follicle-associated Epithelium in the Colon of Calves

Veterinary Pathology ◽

10.1177/030098589202900204 ◽

1992 ◽

Vol 29 (2) ◽

pp. 120-128 ◽

Cited By ~ 14

Author(s):

M. Paar ◽

E. M. Liebler ◽

J. F. Pohlenz

Keyword(s):

Small Intestine ◽

Large Intestine ◽

M Cells ◽

Multivesicular Bodies ◽

Ascending Colon ◽

Intercellular Spaces ◽

Antigen Uptake ◽

Follicle Associated Epithelium ◽

Apical Vesicles ◽

Lymphoid Nodules

Uptake of macromolecules (e.g., ferritin) by M cells in follicle-associated epithelium in small and large intestine was investigated in three healthy, conventionally raised, 2- to 3-week-old, female Holstein Frisian calves. A 2.5% solution of ferritin was injected into the ligated loops in mid-jejunum, in terminal ileum, in the ascending colon adjacent to the ileocecal junction, and in the proximal loop of the ascending colon containing gut-associated lymphoid tissue. After exposure times that ranged from 82 to 165 minutes, ferritin was detected in M cells of domes in the small intestine, as well as in cells in follicle-associated epithelium of proprial lymphoid nodules and lymphoglandular complexes of colon that morphologically resembled M cells of small intestine. Ferritin was found in apical invaginations, apical vesicles, multivesicular bodies, basal vesicles, and adjacent intercellular spaces. In addition to ferritin, apical vesicles, multivesicular bodies, and intercellular spaces contained 50-nm membrane-bound particles. More ferritin was endocytosed by M cells of the small intestine than by M cells of the large intestine. In the large intestine, higher amounts of ferritin were found in M cells of follicle-associated epithelium overlying proprial lymphoid nodules than in M cells of follicle-associated epithelium in the depth of lymphoglandular complexes. Based on these results, we concluded that M cells of follicle-associated epithelium in the colon of calves provide a route for antigen uptake into the intestinal lymphoid system.

Download Full-text