Anaphylactic Shock after Intravenous Injection of Penicillin in a Patient with Maxillary Osteonecrosis: Report of a Case

2014 ◽  
Vol 14 (4) ◽  
pp. 243
Author(s):  
Ji-Hyeon Oh ◽  
Jeong-Seog Son ◽  
Byung-Ho Choi ◽  
Jeong-Sub Lee ◽  
Ji-Hun Kim ◽  
...  
Keyword(s):  
Intravenous Injection ◽  
Anaphylactic Shock

scholarly journals Passive Anaphylaxis following the immediate injection of Antigen after Antiserum

1936 ◽  
Vol 36 (4) ◽  
pp. 570-587 ◽  
Author(s):  
H. R. Dean ◽  
R. Williamson ◽  
G. L. Taylor
Keyword(s):  
Guinea Pig ◽  
Intravenous Injection ◽  
Anaphylactic Shock ◽  
The Body ◽  
Post Mortem ◽  
Abdominal Symptoms ◽  
Respiratory Embarrassment

1. Our experiments show that an intravenous injection of antigen immediately after an intravenous injection of antiserum in the guinea-pig were followed by:(a) Acute shock and death within 5 min. The signs and post-mortem appearances were indistinguishable from acute anaphylactic shock as typically seen in the guinea-pig. Some control animals injected with antiserum only died in a way similar to those which received both antiserum and antigen. These are discussed in detail in the body of the paper.(b) Delayed shock and death some hours later. The post-mortem appearances were those of gastro-intestinal congestion and haemorrhage resembling the changes seen in dogs dying of anaphylactic shock. Such changes were never seen in the control animals.(c) Recovery. Practically all the animals which recovered had symptoms of respiratory embarrassment immediately following the injections of anti-serum and antigen and many had later symptoms of abdominal shock. The animals which were given an injection of antiserum only rarely had any symptoms and never abdominal symptoms.2. It is necessary to test the antisera used by control inoculation since some antisera are toxic.

scholarly journals Reversed passive anaphylaxis in the guinea-pig

1940 ◽  
Vol 40 (4) ◽  
pp. 377-395 ◽  
Author(s):  
M. van den Ende
Keyword(s):  
Guinea Pig ◽  
Intravenous Injection ◽  
Guinea Pigs ◽  
Anaphylactic Shock ◽  
Cellular Mechanism ◽  
Rabbit Serum ◽  
Rabbit Antibody ◽  
Egg Albumin

Attempts to demonstrate reversed passive anaphylaxis in the guinea-pig with crystalline egg albumin as sensitizing antigen have been uniformly negative.When purified anti-pneumococcal antibody globulin was used as sensitizing antigen, reversed anaphylactic shock could be elicited in guinea-pigs by the intravenous injection of precipitins for the antibody globulin.The mild reactions which could be elicited when the total globulins from the serum of normal rabbits were used as sensitizing antigen are probably dependent on the presence of small amounts of y globulin.Reversed passive anaphylaxis, like direct anaphylaxis, is dependent on a cellular mechanism, and the success of experiments in which rabbit antibody globulin was used as sensitizing antigen depends on the acceptability of the antibody to the cells of the guinea-pig's tissues.Antigenic differences between antibody globulins and total normal globulins from rabbit serum are noted.

scholarly journals DISTURBANCES OF THE HEART-BEAT IN THE DOG CAUSED BY SERUM ANAPHYLAXIS

1913 ◽  
Vol 18 (5) ◽  
pp. 556-571 ◽  
Author(s):  
G. Canby Robinson ◽  
John Auer
Keyword(s):  
Blood Pressure ◽  
Right Ventricle ◽  
Short Duration ◽  
Intravenous Injection ◽  
Anaphylactic Shock ◽  
Horse Serum ◽  
Heart Beat ◽  
Inhibitory Mechanism ◽  
The Right

Anaphylactic shock in the dog, caused by the intravenous injection of horse serum into sensitized animals, may produce definite cardiac disturbances which are revealed by the electrocardiogram. These cardiac changes consist of disturbances in conduction of the heart impulses, abnormalities in the ventricular contractions, and other unusual disturbances of the mechanism of the heart-beat. They come on very quickly after the injection of serum and may be of short duration, and are not obtained during anti-anaphylaxis. They are not the result of the marked fall in blood pressure which occurs, nor does the central cardiac inhibitory mechanism play a part in their production. These cardiac disturbances apparently are a definite primary expression of anaphylactic shock in the dog. The right ventricle seems to be more affected than the left.

scholarly journals Late Deaths occurring in Active Anaphylaxis

1936 ◽  
Vol 36 (4) ◽  
pp. 588-593 ◽  
Author(s):  
Raymond Williamson
Keyword(s):  
Guinea Pig ◽  
Intravenous Injection ◽  
Anaphylactic Shock ◽  
Post Mortem ◽  
Late Death

Conditions are described under which late death from active anaphylaxis occurred in the guinea-pig. The post-mortem appearances were those of gastrointestinal congestion and haemorrhage resembling the changes seen in dogs dying of anaphylactic shock.Late deaths can be produced by the intravenous injection of antigen but more easily by intraperitoneal injections.

scholarly journals THE RÔLE OF THE RETICULO-ENDOTHELIAL SYSTEM IN IMMUNITY

1926 ◽  
Vol 44 (1) ◽  
pp. 129-145 ◽  
Author(s):  
C. W. Jungeblut ◽  
J. A. Berlot
Keyword(s):  
Intravenous Injection ◽  
Normal Control ◽  
Guinea Pigs ◽  
Anaphylactic Shock ◽  
India Ink ◽  
Passive Sensitization ◽  
Normal Controls ◽  
Reticulo Endothelial System

1. Guinea pigs injected intravenously with massive doses of India ink before active sensitization exhibited occasionally a more or less marked, decreased sensitiveness to the reinjection of the antigen. 2. The serum of rabbits which had received massive doses of India ink before the sensitizing injections, showed approximately the same titer of anaphylactic antibodies as that of sensitized normal control animals, as demonstrated by the degree of passive sensitization induced in guinea pigs. 3. The precipitin titer of sensitized rabbits blocked with massive doses of India ink was somewhat lower than that of sensitized normal controls. In one instance, the intravenous injection of smaller doses of India ink was followed by a higher precipitin titer. No uniform relation was found between the height of the precipitin titer and the anaphylactic power of the antiserums. 4. One blocking injection of India ink given to guinea pigs before passive sensitization did not interfere with the occurrence of anaphylactic shock nor alter its nature.

The Local Sanarelli-Shwartzman Phenomenon in Rats Induced by Human Leukaemic Cells

1973 ◽  
Vol 29 (02) ◽  
pp. 353-362
Author(s):  
J Lisiewicz ◽  
A Pituch ◽  
J. A Litwin
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
Intravenous Injection ◽  
Peripheral Blood ◽  
Lymphocytic Leukaemia ◽  
Acute Myeloblastic Leukaemia ◽  
Demarcation Line ◽  
E Coli ◽  
Leukaemic Cells ◽  
Shwartzman Phenomenon

SummaryThe local Sanarelli-Shwartzman phenomenon (SSP-L) in the skin of 30 rats was induced by an intr a cutaneous sensitizing injection of leukaemic leucocytes isolated from the peripheral blood of patients with chronic lymphocytic leukaemia (CLL), acute myeloblastic leukaemia (AL) and chronic granulocytic leukaemia (CGL) and challenged by an intravenous injection of 100(μ of E. coli endotoxin. SSP-L was observed in 7 rats after injection of CLL lymphocytes and in 6 and 2 rats after AL myeloblasts and the CGL granulocytes, respectively. The lesions in the skin after AL myeloblasts appeared in a shorter time and were of longer duration compared with those observed after CLL lymphocytes and CGL granulocytes. Histologically, the lesions consisted of areas of destruction in the superficial layers of the skin ; the demarcation line showed the presence of neutrophils, macrophages and erythrocytes. Haemorrhages and fibrin deposits near the demarcation line were larger after injection of CLL lymphocytes and AL myeloblasts than after CGL granulocytes. The possible role of leucocyte procoagulative substances in the differences observed have been discussed.

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