scholarly journals A comparative study of endoscopic findings, Rapid Urease Test and Conventional Histopathology in diagnosis of Helicobacter Pylori infection

2017 ◽  
Vol 3 (3) ◽  
pp. 242-247
Author(s):  
Dr Shashikant Adlekha ◽  
◽  
Dr Tandra Chadha ◽  
Keyword(s):  
Helicobacter Pylori ◽  
Comparative Study ◽  
Helicobacter Pylori Infection ◽  
Rapid Urease Test ◽  
Endoscopic Findings ◽  
Urease Test

scholarly journals Correlation between rapid urease test and pathohistological gastrobiopsy finding with positive immunological test in detecting Helicobacter pylori infection

2011 ◽  
Vol 64 (7-8) ◽  
pp. 413-417 ◽  
Author(s):  
Ivana Naumov ◽  
Atila Fenjvesi
Keyword(s):  
Helicobacter Pylori ◽  
Serological Test ◽  
Endoscopic Examination ◽  
Helicobacter Pylori Infection ◽  
Rapid Urease Test ◽  
Ulcer Disease ◽  
Endoscopic Findings ◽  
Urease Test ◽  
Immunological Test ◽  
Immunologic Test

Introduction. Helicobacter pylori is a bacterium that has been in the limelight of gastroenterologists and oncologists worldwide since its immediate effect on the development of gastritis, ulcer disease, mucosa-associated lymphoid tissue lymphoma and gastric cancer was proved. The aim of this study was to determine the correlation between the positive immunological test, rapid urease test and pathohistological finding in detecting Helicobacter pylori infection of the gastric mucosa. Material and Methods. This retrospective study included 250 endoscopic findings of subjects having undergone endoscopy in the first half of 2010 at the Ward of Gastroenterology, Department of Internal Diseases, Hospital in Senta. The endoscopy procedure was performed by Fujinon endoscopes and the fast urease test was done by the Cambridge Life Science set from England. The immunological test was carried out by the Vidas apparatus applying the Enzyme-Linked Fluorescent Assay (ELFA) technique and the staining for the pathohistological analysis was done by the modified Giemsa method. Results. The paper presents the results obtained by endoscopic examination of a group of 250 patients performed at the Ward of Gastroenterology, Department of Internal Diseases, Hospital in Senta. The endoscopic findings were the first to be analyzed then the rapid urease test findings, which showed that 95 (38%) patients were positive and 155 (62%) patients were negative; whereas the immunologic test for Helicobacter pylori was positive in all 250 patients (100%). The histological test for Helicobacter-Like Organism was positive in 105 subjects (42%), whereas it was negative in 145 patients, that being 58% of all the cases. Sensitivity, specificity and predictability of the serological test and the rapid urease test were calculated according to the pathohistological finding as the ?gold standard? and they were found to be: sensitivity 100% and specificity 0% for the serological test and sensitivity 90% and specificity 100% for the rapid urease test. The immunologic test was not correlated with other findings, and there was a high level of correlation between the rapid urease test and histological test (r=0.927589261). The t-test was calculated to be 36.16513; p=0.0001; that indicating that the correlation coefficient was statistically significant (p>0.01). Discussion. The obtained results were compared with the data found in the available literature sources. Conclusion. It can be concluded that the most competent technique for the optimal diagnosis of Helicobacter pylori infection is the invasive one with the pathohistological examination of bioptates together with the rapid urease test.

scholarly journals Association of gastric infection and periodontal disease through Helicobacter pylori as a common denominator: A systematic review and meta-analysi

2021 ◽  
Author(s):  
Nansi López-Valverde ◽  
◽  
Antonio López-Valverde ◽  
Ana Suarez ◽  
Bruno Macedo de Sousa ◽  
...  
Keyword(s):  
Systematic Review ◽  
Helicobacter Pylori ◽  
Clinical Studies ◽  
Periodontal Diseases ◽  
Meta Analysis ◽  
Helicobacter Pylori Infection ◽  
Enzyme Linked Immunosorbent Assay ◽  
Rapid Urease Test ◽  
Common Denominator ◽  
Urease Test

Review question / Objective: Is gastric helicobacter pylori infection related to periodontal diseases? Condition being studied: Therefore, the aim of this systematic review and meta-analysis was to identify and analyze clinical studies to determine the direct correlation between Helicobacter Pylori gastric infection andPeriodontal Disease. Study designs to be included: Clinical studies that provided data on Helicobacter Pylori infection in both the stomach and oral cavity, confirmed by polymerase chain reaction (PCR), rapid urease test (RUT) or enzyme-linked immunosorbent assay (ELISA). Clinical studies that associated PD with Helicobacter Pylori. The diagnosis of PD was confirmed ac-cording to the diagnostic criteria in periodontology.

Endoscopic Tests for the Diagnosis of Helicobacter pylori Infection in Children: Validation of Rapid Urease Test

Helicobacter ◽  
2010 ◽  
Vol 15 (3) ◽  
pp. 227-232 ◽  
Author(s):  
Eleftheria Roma-Giannikou ◽  
Alkaterini Roubani ◽  
Dionyssios N. Sgouras ◽  
Joanna Panayiotou ◽  
Catherine Van-Vliet ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Helicobacter Pylori Infection ◽  
Rapid Urease Test ◽  
Urease Test

HUITAI rapid urease test: A new ultra-rapid biopsy urease test for the diagnosis of Helicobacter pylori infection

2007 ◽  
Vol 8 (3) ◽  
pp. 139-142 ◽  
Author(s):  
Khean-Lee GOH ◽  
Phaik-Leng CHEAH ◽  
Parasakthi NAVARATNAM ◽  
Sow-Chan CHIN ◽  
Shu-Dong XIAO
Keyword(s):  
Helicobacter Pylori ◽  
Helicobacter Pylori Infection ◽  
Rapid Urease Test ◽  
Urease Test

Evaluation of a new reagent strip rapid urease test for detection of Helicobacter pylori infection

1996 ◽  
Vol 44 (5) ◽  
pp. 519-522 ◽  
Author(s):  
Mahmoud M. Yousfi ◽  
Hala M.T. El-Zimaity ◽  
Robert M. Genta ◽  
David Y. Graham
Keyword(s):  
Helicobacter Pylori ◽  
Helicobacter Pylori Infection ◽  
Rapid Urease Test ◽  
Urease Test

scholarly journals European Registry on the management of Helicobacter pylori infection: features of diagnosis and treatment in Kazan

2020 ◽  
Vol 92 (8) ◽  
pp. 52-59
Author(s):  
S. R. Abdulkhakov ◽  
D. S. Bordin ◽  
R. A. Abdulkhakov ◽  
D. D. Safina ◽  
A. R. Gizdatullina ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Proton Pump Inhibitor ◽  
Triple Therapy ◽  
Proton Pump ◽  
Eradication Therapy ◽  
Helicobacter Pylori Infection ◽  
Rapid Urease Test ◽  
Standard Triple Therapy ◽  
Urease Test ◽  
H Pylori

Background. As part of an observational multicenter prospective study European Registry on the management of Helicobacter pylori infection, conducted on the initiative of the European H. pylori and Microbiota Study Group, the compliance of clinical practice in the management of patients with Helicobacter pylori infection in Kazan with clinical guidelines was assessed. Materials and methods. The data of 437 patients included into the register by clinical sites in Kazan in 20132019 were analyzed. The methods used for the initial diagnosis of H. pylori infection and eradication control were evaluated. The frequency of various eradication therapy regimens prescription was analyzed in 379 cases. Data regarding the effectiveness of eradication therapy was analyzed in 173 patients. Results. The rapid urease test (44.2% of cases) and cytology/histology (60% of cases) were most often used for the initial diagnosis of H. pylori infection; however non-invasive methods such as 13C-urea breath (9.2%), serology (6.2%), H. pylori stool antigen test (2.3%) were less common. In 21.7% of patients two methods of H. pylori detection were used for primary diagnosis. The control test to evaluate the effectiveness of eradication therapy at the recommended timepoint was performed in 46.2% of patients. 13C-urea breath test (31.7%), stool PCR/stool antigen test (28.7%), rapid urease test (22.3%), cytology/histology (26.2% of cases) prevailed in the assessment of eradication rate. Standard triple therapy, including proton pump inhibitor, clarithromycin and amoxicillin was most commonly prescribed as first-line therapy (64.6% of cases). The duration of eradication therapy was 14 days in the majority of cases with pantoprazole as the most common proton pump inhibitor in standard triple therapy regimens (84.8%). The efficacy of 14-day standard triple therapy (mITT) was 87.0%. Conclusion. The results indicate a high frequency of non-invasive methods use for assessing the effectiveness of eradication therapy; however, the overall rate of eradication efficacy assessment is low, limiting the possibility of analyzing the eradication results. The effectiveness of the most common 14-day standard triple first-line therapy in Kazan doesnt reach the recommended 90% eradication level. This could be explained by high rate of pantoprazole use, which is not an optimal proton pump inhibitor in eradication therapy regimens.

Comparison of Helicobacter Pylori Detection: it's Association with Leukocytosis and Monocytosis

2020 ◽  
Vol 20 ◽  
Author(s):  
Monireh Rahimkhani ◽  
Alireza Mordadi ◽  
Kiana Kazemian ◽  
Hourieh Khalili
Keyword(s):  
Helicobacter Pylori ◽  
Standard Method ◽  
Gold Standard ◽  
Clinical Signs ◽  
Helicobacter Pylori Infection ◽  
Rapid Urease Test ◽  
Blood Monocytes ◽  
Gold Standard Method ◽  
Noninvasive Diagnostics ◽  
Urease Test

Background: Helicobacter pylori is a slow-growing micro-aerophilic gram-negative organism found in stomach and duodenum. It is also associated with a number of stomach-duodenal diseases. Material and Methods: There are invasive and non-invasive methods for detecting Helicobacter pylori infections. In a 13- months period, 101 patients with clinical signs of infection confirmed by biopsy and Rapid Urease test as well as culture were included to this study. Results: There were significant correlations between breath urease test, anti-Helicobacter pylori serum IgG and IgA as well as fecal Helicobacter pylori Ag with gold standard method,(P=0.001) Moreover, there was significant correlation between monocytosis (P= 0.05) and gold standard method. Conclusion: Based on studies conducted on patients with Helicobacter pylori infection, noninvasive diagnostics methods can be useful in the diagnosis of Helicobacter infections rather than evaluating anti-Helicobacter pylori serum IgM and also increased blood monocytes could be a reliable confirmation for detection. Furthermore, showed monocytosis must be considered as a Helicobacter pylori infection at first step in area with high infected percentage.

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