scholarly journals Laryngeal cancer in two non-consanguineous people (spouses): a case report

2020 ◽  
Vol 10 (2) ◽  
pp. 85-89
Author(s):  
L. G. Kozhanov ◽  
А. L. Kozhanov ◽  
Yu. Yu. Vyaltseva ◽  
А. V. Egorova ◽  
S. V. Chulkova
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
Female Patient ◽  
Laryngeal Cancer ◽  
Rare Case ◽  
Malignant Tumors ◽  
Hpv Infection ◽  
Head And Neck Tumors ◽  
Neck Tumors ◽  
Close Relatives

The objective is to report a rare case of laryngeal cancer in spouses. Case report. A 59-year-old female patient was admitted to the Department of Head and Neck Tumors in December 2019 with complaints of hoarseness. In 1997, she had radiotherapy for T1N0M0 laryngeal cancer. After comprehensive examination, she was diagnosed with recurrent laryngeal cancer. The patient has undergone frontolateral laryngeal resection. A 67-year-old male patient was admitted to the Department of Head and Neck Tumors in November 2019 with T3N0M0 laryngeal cancer (diagnosed 2 months before). He has undergone extended frontolateral laryngeal resection followed by radiotherapy in the postoperative period. Discussion. Both patients had no risk factors, such as occupational hazards or smoking. However, both spouses had close relatives with cancer, what indicates their genetic predisposition to malignant tumors. The female patient was found to have human papilloma virus (HPV) in the tumor cells, whereas her spouse was HPV-negative, although rapid histology showed indirect signs of HPV, which does not exclude the elimination of HPV. Conclusion. In this rare case of laryngeal cancer diagnosed in two non-consanguineous spouses, the disease is likely to be caused by their hereditary predisposition, HPV infection, and the fact that they lived in the same socioeconomic conditions.

Markers of HPV infection and survival in patients with head and neck tumors

2013 ◽  
Vol 133 (8) ◽  
pp. 1832-1839 ◽  
Author(s):  
Eva Koslabova ◽  
Eva Hamsikova ◽  
Martina Salakova ◽  
Jan Klozar ◽  
Eva Foltynova ◽  
...  
Keyword(s):  
Head And Neck ◽  
Hpv Infection ◽  
Head And Neck Tumors ◽  
Neck Tumors

scholarly journals Undifferentiated carcinoma of parapharyngeal space in 8 year old female child: a rare case presentation

2016 ◽  
Vol 2 (2) ◽  
pp. 88
Author(s):  
Ramesh Kadela ◽  
Sonia Jindal ◽  
Pooja Arya ◽  
Niranjan Nagaraj ◽  
Deepchand Lal ◽  
...  
Keyword(s):  
Head And Neck ◽  
Malignant Tumor ◽  
Rare Case ◽  
Parapharyngeal Space ◽  
Female Child ◽  
Undifferentiated Carcinoma ◽  
Head And Neck Tumors ◽  
Case Presentation ◽  
Parapharyngeal Space Tumors ◽  
Neck Tumors

<p class="abstract">Parapharyngeal space tumors represent only 0.5% of all head and neck tumors. Out of which, 80% are benign and 20% are malignant. Tumor must be at least 2 cm in size before bulge or abnormality is palpable. We report a case of 8 year old female child who presented with bulge in right tonsillar region. </p>

Accumulation of 99mTc-Glutathione in Head and Neck Tumors

1994 ◽  
Vol 33 (05) ◽  
pp. 224-228 ◽  
Author(s):  
T. Aras ◽  
A. Aktaş ◽  
S. Kaya ◽  
C. F. Bekdik ◽  
M. T. Ercan
Keyword(s):  
Head And Neck ◽  
Soft Tissues ◽  
Malignant Tumors ◽  
False Negative ◽  
Neck Region ◽  
Head And Neck Tumors ◽  
Blood Clearance ◽  
True Negative ◽  
Head And Neck Region ◽  
Neck Tumors

SummaryGlutathione labelled with 99mTc was used to study blood clearance and normal distribution in 3 healthy volunteers and in 10 patients with biopsy-proven tumors in the head and neck region. Static scintigrams were obtained at 1, 3, 6, and 24 h. ROIs over tumors and normal soft tissues were compared to obtain T/N ratios. In normal subjects blood clearance reached a plateau at 6 h; no radioactivity accumulation in the head and neck region was observed. Only the cardiac blood pool, the liver, the kidneys and the urinary bladder were evident. Excretion was via the kidneys. Malignant tumors and metastases were well visualized in 7 patients (true-positive), starting at 1 h. The mean T/N ratio was 2.69 ± 0.77. The best images were obtained at 3-6 h. 1 false-positive (granula-matous reaction), 1 false-negative (malignant epithelial tumor in the radix of tongue) and 1 true-negative (angiofibroma) results were obtained. 99mTc-GSH is a potential radiopharmaceutical for the scintigraphic visualization of head and neck tumors. Further clinical studies are warranted to show its sensitivity and accuracy.

Vascular Problems Associated with The Management of Head and Neck Tumors—A Case Report

1990 ◽  
Vol 24 (7) ◽  
pp. 530-535
Author(s):  
Gary W. Barone ◽  
Curtis G. Tribble ◽  
Irving L. Kron
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
Head And Neck Tumors ◽  
Neck Tumors

scholarly journals Keratocystic Odontogenic Tumor with ameloblastomatic changes mimicking dentigerous cyst : An unusual case report

2020 ◽  
Vol 6 (2) ◽  
pp. 57-60
Author(s):  
Manjula Marandi ◽  
Sonal Saigal ◽  
Narendra Nath Singh
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
Dentigerous Cyst ◽  
The Body ◽  
Head And Neck Tumors ◽  
Biological Behavior ◽  
Keratocystic Odontogenic Tumor ◽  
Recurrence Rates ◽  
Dental Lamina ◽  
Neck Tumors

The OdontogenicKeratocystic (OKC) is a developmental cyst derived from the remanants (rest) of the dental lamina with a peculiar biological behavior. Many attempts have been made to classify these cysts from 1887 to WHO 2017 head and neck tumors.  Initially classified under developmental odontogenic cyst of jaw by WHO in 1971 and 1992, OKC has then been reclassified and renamed as KeratocysticOdontogenic Tumor (KCOT) in the WHO classifications of head and neck tumors in 2005 due to its aggressive behavior, high recurrence rates and specific histopathological feature. But recently WHO 2017 classification of head and neck tumors reclassified KCOT as a cyst. Despite of so many classification and nomenclature, unfortunately the controversy still exists. KCOT has been rarely reported to transform into a more aggressive lesion like ameloblastoma. We here present a case report of KCOT involving the body and ramus of the mandible having histopathological features suggestive of ameloblastomatic changes and mimicking dentigerous cyst.

scholarly journals The Larynx Carcinomas in West Serbia

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 8s-8s
Author(s):  
S. Majstorovic ◽  
N. Majstorovic
Keyword(s):  
Head And Neck ◽  
Malignant Tumors ◽  
Histopathological Examination ◽  
Head And Neck Tumors ◽  
Benign Lesions ◽  
Male Population ◽  
Larynx Carcinoma ◽  
Female Patients ◽  
Neck Tumors ◽  
Regional Metastases

Background: Malignant tumors of the larynx account for 20% of all malignant head and neck tumors, and 45% of all epithelial head and neck tumors, as well as 2% of all malignant tumors. They commonly occur among the population of 50-70 years of age, and quite rarely among the population under 20 years of age, and affect predominantly male population. The larynx is located at the intersection of the respiratory and digestive ducts. It consists of a number of cartilages mutually connected by joints, muscles and connective tissue. Anatomically, clinically and oncologically speaking, the larynx is divided into three sections: supraglottis, glottis and subglottis. The supraglottis tumors dominate over the glottis tumors while the subglottis tumors are the least frequent and occur with approximately 5% of the patients. The larynx carcinomas produce regional metastases on the neck and more distant organs such as the lungs, the liver and the brain. Aim: The survey covers the five-year period, from 2010-2015, during which LMS (laryngomicroscopic procedures) were performed on the patients from municipality of Čačak and West Serbia and results obtained upon the histopathological examination of the biopsy-taken tissues of the above patients. Methods: Diagnosis, estimation of the logically and the extent of tumor are performed according to the following method of operation: 1. Case history 2. Clinical examination 3. Endoscopic examination and RTG examination. Endoscopic methods: 1. Indirect laryngoscopy 2. DSC and LMS (directoscopy and laryngomicroscopy) 3. Fib laryngoscopy 4. ESC (esophagoscopy), due to the tendency of tumor to spread to hypopharynx 5. TBSC (tracheobronchoscopy) 6. Stroboscopy. The essential procedures in the larynx carcinoma therapy are as follows: 1. To assess the locality and extent of the tumor 2. To ascertain the PH with specific histologic paraments (nuclear and histologic graduation) 3. To assess the extent of the tumor in the region. Results: The total of 305 LMS procedures were performed, out of which 225 on male and 80 LMS on female patients. There were 207 (68%) patients with benign lesions and 98 patients (32%) with larynx carcinomas. The larynx carcinoma was found in 90% of the male and 10% of the female patients. The youngest patient aged 26, while the oldest one was 82 years of age. The benign lesions took the forms of polyps, papillomas, hemangiomas and chronic inflammation of the larynx mucous membrane. Conclusion: The exposure of the larynx epithelium to various air pollutants and tobacco smoke especially, causes numerous changes in the organ which may range from harmless acute inflammation to cancerogenic conditions.

scholarly journals Parapharyngeal Schawannnoma. Case Report

2021 ◽  
Vol 21 (4) ◽  
pp. 874-880
Author(s):  
Enrique Moyano Navarro ◽  
Manuel Inostroza Fernández ◽  
Pedro P. Sotelo Jiménez ◽  
Ethel Vargas Carrillo ◽  
Alan La Torre Zúñiga ◽  
...  
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Head And Neck ◽  
Female Patient ◽  
Parapharyngeal Space ◽  
Incisional Biopsy ◽  
Neck Tumors ◽  
Low Incidence ◽  
Parapharyngeal Tumor ◽  
Slow Growing

Parapharyngeal tumor lesions present a low incidence, representing between 0,5 and 0,8% of all head and neck tumors. Approximately 80% show benign behavior. The uniqueness of these lesions derives from their complex anatomical situation and the symptoms with which they usually appear, being in most cases nonspecific and almost always derived from the compressive effect produced by the lesion on the oropharynx and the oropharynx. Schwannomas of the parapharyngeal space are very rare tumors that originate from the sheath of schawnn, generally slow growing, and are usually asymptomatic. Treatment is surgical, often complex due to the anatomical location.The case of a 42-year-old female patient with a diagnosis of Schwannoma in the left parapharyngeal region, demonstrated by incisional biopsy, is presented; undergoing surgical treatment, which was carried out without complications.

Statistical Study of 275 Cases of Head and Neck Tumors in Childhood

1969 ◽  
Vol 55 (4) ◽  
pp. 225-239
Author(s):  
Roberto Molinari ◽  
Alessandro Zappata
Keyword(s):  
Head And Neck ◽  
Statistical Study ◽  
Malignant Tumors ◽  
Head And Neck Tumors ◽  
Cns Tumors ◽  
Benign Tumors ◽  
Head And Neck Neoplasm ◽  
Thyroid Adenoma ◽  
Neck Tumors ◽  
Age And Sex

275 cases of head and neck tumors were observed among patients from 0 to 17 years of age at the National Cancer Institute of Milan during the forty year period 1928–1968. Because of possible preselection of the case material, cutaneous angiomas, retinoblastomas, adamantinomas and central nervous system (CNS) tumors were excluded from this series. All cases were evaluated from the viewpoint of histogenesis, site, age and sex. From the analysis of the different cases we can point out that: 1) if CNS tumors and retinoblastoma are excluded, no type of head and neck neoplasm is absolutely characteristic of childhood. 2) Angioma is the most common benign growth, followed by thyroid adenoma, nevus and parotid gland mixed tumor; among malignant tumors, the most frequent are solid and lymphoreticular sarcomas followed with a much lower incidence by carcinoma of nasopharynx. 3) The epithelial investment very rarely gives origin to malignant tumors, which are predominantly found in the nasopharynx. 4) A part from some exceptions, the general incidence of all benign and malignant tumors increases proportionally with age. 5) Benign tumors are more common among females while malignant tumors among males. 6) Rhabdomyosarcoma of the head and neck area is located almost solely in the soft palate.

Epidemiological and anatomopathological features of pediatric head and neck tumors in Benin

2019 ◽  
Vol 11 (4) ◽  
pp. 196-199
Author(s):  
Spéro H Raoul Hounkpatin ◽  
Luc Valere C Brun ◽  
Marie Claire Balle ◽  
Tire Abdias Bossou ◽  
Fatiou Alabi Bouraima ◽  
...  
Keyword(s):  
Head And Neck ◽  
Maxillary Sinus ◽  
Malignant Tumors ◽  
Research Work ◽  
Head And Neck Tumors ◽  
Benign Tumors ◽  
Tissue Mass ◽  
Cross Sectional ◽  
Neck Tumors

Objective: This research work aims to investigate the epidemiological and anatomopathological characteristics of ENT and head and neck tumors among children in Benin. Materials and methods: It was a cross-sectional and descriptive study carried out from January 1, 2009 to December 31, 2014. It was focused on all the reports of anatomopathological examinations of ENT, head and neck tissue mass among subjects aged no more than 15years identified in Benin and whose histological diagnosis was a tumor. Findings: Among a total of 611ear, nose-& throat (ENT), head and neck tumors colligated, 100 were about children (16.4%). These were 23 cases of malignant tumors and 77 cases of benign tumors. Sex ratio was 1.3 for all the tumors; it was 1.1 for benign tumors and 2.3 for malignant tumors. Cancers were primarily located in the pharynx with 9 cases out of 23, followed by 7 cases in nose and maxillary sinus. Benign tumors were mainly related to nose and maxillary sinus with 30 cases (39% of benign tumors) and larynx with 24cases (31.2%). Various histological types were investigated. As regards cancers, they were mainly squamous cell carcinoma cancers (8 cases out of 23 cancers); and benign tumors were mainly papilloma (46.8%) followed by fibroma (16.9%) and hemangioma (13%). Conclusion: The predominance of papillomas suggests the possibility of prevention due to the important role of human papillonavirus (HPV) in their genesis.

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