A SYNTHETIC CELL-PENETRATING PEPTIDE (CPP) WITH PROTAMINE CONJUGATE UTILIZED FOR GENE DELIVERY

2012 ◽  
Vol 2 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Beston F. Nore ◽  
Keyword(s):  
Gene Delivery ◽  
Cell Penetrating Peptide ◽  
Synthetic Cell ◽  
Cell Penetrating

Bioreducible branched poly(modified nona-arginine) cell-penetrating peptide as a novel gene delivery platform

2017 ◽  
Vol 246 ◽  
pp. 142-154 ◽  
Author(s):  
Jisang Yoo ◽  
DaeYong Lee ◽  
Vipul Gujrati ◽  
N. Sanoj Rejinold ◽  
Kamali Manickavasagam Lekshmi ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Cell Penetrating Peptide ◽  
Novel Gene ◽  
Cell Penetrating ◽  
Delivery Platform

scholarly journals A Cell-Penetrating Peptide with a Guanidinylethyl Amine Structure Directed to Gene Delivery

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Makoto Oba ◽  
Takuma Kato ◽  
Kaori Furukawa ◽  
Masakazu Tanaka
Keyword(s):  
Gene Delivery ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating ◽  
Amine Structure ◽  
A Cell

scholarly journals A Synthetic Cell-Penetrating Peptide Antagonizing TrkA Function Suppresses Neuropathic Pain in Mice

2010 ◽  
Vol 114 (1) ◽  
pp. 79-84 ◽  
Author(s):  
Wei-Ying Ma ◽  
Eri Murata ◽  
Koyo Ueda ◽  
Yoshihiro Kuroda ◽  
Ming-Hui Cao ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Cell Penetrating Peptide ◽  
Synthetic Cell ◽  
Cell Penetrating

scholarly journals Highly versatile cell-penetrating peptide loaded scaffold for efficient and localised gene delivery to multiple cell types: From development to application in tissue engineering

Biomaterials ◽  
2019 ◽  
Vol 216 ◽  
pp. 119277 ◽  
Author(s):  
Rosanne M. Raftery ◽  
David P. Walsh ◽  
Lia Blokpoel Ferreras ◽  
Irene Mencía Castaño ◽  
Gang Chen ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Gene Delivery ◽  
Cell Types ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating ◽  
Multiple Cell

Dual-functionalized calcium carbonate based gene delivery system for efficient gene delivery

RSC Advances ◽  
2014 ◽  
Vol 4 (73) ◽  
pp. 38623-38629 ◽  
Author(s):  
Chao-Qun Wang ◽  
Meng-Qing Gong ◽  
Jin-Long Wu ◽  
Ren-Xi Zhuo ◽  
Si-Xue Cheng
Keyword(s):  
Calcium Carbonate ◽  
Gene Delivery ◽  
Delivery System ◽  
Gene Transfection ◽  
Cell Penetrating Peptide ◽  
Gene Delivery System ◽  
Dna Nanoparticles ◽  
Efficient Gene ◽  
Cell Penetrating ◽  
A Cell

Dual-functionalized KALA/PS/CaCO3/DNA nanoparticles containing a cell penetrating peptide (KALA) and protamine sulfate (PS) could effectively mediate gene transfection at a low DNA concentration.

scholarly journals Cell-penetrating peptide-labelled smart polymers for enhanced gene delivery

2016 ◽  
Vol 17 (2) ◽  
pp. 193-203 ◽  
Author(s):  
Bingyang Zhang ◽  
Hu Zhang ◽  
Sheng Dai ◽  
Jingxiu Bi
Keyword(s):  
Gene Delivery ◽  
Cell Penetrating Peptide ◽  
Smart Polymers ◽  
Cell Penetrating

scholarly journals Local Administration of a Synthetic Cell-Penetrating Peptide Antagonizing TrkA Function Suppresses Inflammatory Pain in Rats

2010 ◽  
Vol 112 (4) ◽  
pp. 438-443 ◽  
Author(s):  
Koyo Ueda ◽  
Munetaka Hirose ◽  
Eri Murata ◽  
Mayumi Takatori ◽  
Masashi Ueda ◽  
...  
Keyword(s):  
Inflammatory Pain ◽  
Local Administration ◽  
Cell Penetrating Peptide ◽  
Synthetic Cell ◽  
Cell Penetrating

scholarly journals A simple and efficient transfection protocol for Cryptosporidium parvum using Polyethylenimine (PEI) and Octaarginine

Parasitology ◽  
2020 ◽  
Vol 147 (10) ◽  
pp. 1065-1070
Author(s):  
Tran Nguyen-Ho-Bao ◽  
Maxi Berberich ◽  
Wanpeng Zheng ◽  
Dieter Seebach ◽  
Arwid Daugschies ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Cryptosporidium Parvum ◽  
Plasmid Dna ◽  
Cationic Polymer ◽  
Cell Penetrating Peptide ◽  
Laboratory Equipment ◽  
Short Cell ◽  
Transfection Protocol ◽  
Simple Protocol ◽  
Cell Penetrating

AbstractThe transfection of Cryptosporidium represents a major challenge, and current protocols are based on electroporation of freshly excysted sporozoites using a rather large amount of plasmid DNA which typically has a very poor yield. In this study, we report a fast and simple protocol for transfection of Cryptosporidium parvum that takes advantage of the DNA condensing power of the poly cationic polymer polyethylenimine (PEI) and the gene delivery property of the short cell-penetrating peptide octaarginine. Our novel protocol requires a very low amount of plasmid DNA and does not necessitate special laboratory equipment to be performed. Transfection appears to be more efficient in oocysts just triggered for excystation than the excysted sporozoites. Altogether, the application of octaarginine with PEI allows efficient transfection. To the best of our knowledge, this is the first report on an electroporation-free protocol for transfection of sporozoites of a Cryptosporidium species.

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