Localized Juvenile Spongiotic Gingival Hyperplasia: Report of Two Cases

2017 ◽  
Vol 41 (3) ◽  
pp. 228-231 ◽  
Author(s):  
Eleni-Marina Kalogirou ◽  
Konstantina Chatzidimitriou ◽  
Konstantinos I. Tosios ◽  
Evangelia P. Piperi ◽  
Alexandra Sklavounou
Keyword(s):  
Histological Examination ◽  
Squamous Epithelium ◽  
Inflammatory Cells ◽  
Final Diagnosis ◽  
Pediatric Dentistry ◽  
Gingival Hyperplasia ◽  
Gingival Epithelium ◽  
Stratified Squamous Epithelium ◽  
Maxillary Lateral Incisor ◽  
Shed Light

Objective: Localized juvenile spongiotic gingival hyperplasia (LJSGH) is a painless gingival swelling that histologically exhibits hyperplasia of the non-keratinized stratified squamous epithelium, intercellular edema and spongiosis of the spinus layer, and exocytosis of inflammatory cells. LJSGH pathogenesis remains to be elucidated, while a possible origin from the gingival sulcus epithelium is nowadays proposed. Study design: We report two cases of LJSGH with immunohistochemical evaluation of cytokeratins (CKs) 18 and 19. Results: Both cases concerned 12-year-old boys, who presented with a well-circumscribed bright red pedunculated papillary swelling on the marginal gingiva of the left maxillary lateral incisor. With the provisional diagnosis of LJSGH, the lesions were excised under local anesthesia and histological examination supported the final diagnosis of LJSGH. In both cases, the lesional epithelium showed intense and mild positivity for CK19 and CK18, respectively, while the adjacent normal gingival epithelium expressed CK19, but not CK18, only in the basal cell layer. The postoperative course was uneventful in both patients and no recurrence has been reported. Conclusion: LJSGH is a recently introduced entity that is worth attention in the clinical pediatric dentistry. Clinical and histological examination is required for the final diagnosis, while immunohistochemistry has shed light to LJSGH pathogenesis.

Spontaneous hyperplastic and metaplastic duct epithelium in the sublingual salivary glands of Wistar rats

1986 ◽  
Vol 20 (2) ◽  
pp. 127-131 ◽  
Author(s):  
E. van Esch ◽  
H. C. Dreef-van der Meulen ◽  
V. J. Feron
Keyword(s):  
Salivary Glands ◽  
Small Groups ◽  
Wistar Rats ◽  
Squamous Epithelium ◽  
Fibrous Tissue ◽  
Inflammatory Cells ◽  
Epithelial Hyperplasia ◽  
Duct Epithelium ◽  
Stratified Squamous Epithelium ◽  
Focal Epithelial Hyperplasia

Focal epithelial hyperplasia and metaplasia were observed in the intralobular ducts of the sublingual salivary glands of 302 out of 1142 Wistar rats. These rats (aged 16-145 weeks) served as controls in toxicological experiments. The ductal changes varied from small groups of irregular cylindrical cells with basophilic cytoplasm and vesicular nuclei, with often prominent nucleoli, to large areas of non-keratinized stratified squamous epithelium with marked mitotic activity and necrotic superficial cells being released in the lumen. Mononuclear inflammatory cells were often present in fibrous tissue surrounding altered ducts. Within certain limits the degree and incidence of the changes increased with increasing age; their aetiology is unknown.

Uncommon Coetaneous Histopathological Findings in Radicular Cyst: A Case Report

2020 ◽  
Vol 5 (2) ◽  
pp. 1115-1118
Author(s):  
Shashi Keshwar ◽  
Ashish Shrestha ◽  
Sushmita Shrestha ◽  
Tonia Raut
Keyword(s):  
Case Report ◽  
Squamous Epithelium ◽  
Plasma Cells ◽  
Inflammatory Cells ◽  
Epithelial Lining ◽  
Radicular Cyst ◽  
Histopathological Findings ◽  
Stratified Squamous Epithelium ◽  
Cyst Lining ◽  
Maxillary Region

Radicular cyst is the most common inflammatory cyst of jaw. It arises from the epithelial residues in the periodontal ligaments as a result of pulp infection. Histopathologically radicular cyst lining reveals stratified squamous epithelium with arcade like pattern in early cases or quiescent epithelial lining in long standing cases. The wall of the radicular cyst is fibrous with mixed inflammatory cells infiltrate like neutrophils, plasma cells, lymphocytes and macrophages. There are very few reported cases of juxtaepithelial hyalinization of radicular cyst. Here we report a case of radicular cyst of a 28 year old male who presented with pus discharge from anterior right maxillary region. The cyst was associated with atrophic and tenuous epithelial lining with juxtaepithelial hyalinization along with focal Russell bodies. These findings are uncommoncoeval features of radicular cyst.

scholarly journals Perianal Median Raphe Cyst: A Rare Lesion with Unusual Histology and Localization

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Betül Ünal ◽  
Cumhur İbrahim Başsorgun ◽  
Meryem İlkay Eren Karanis ◽  
Gülsüm Özlem Elpek
Keyword(s):  
Squamous Epithelium ◽  
Final Diagnosis ◽  
Median Raphe ◽  
Ciliated Cells ◽  
Perianal Region ◽  
Penile Shaft ◽  
Rare Location ◽  
Stratified Squamous Epithelium ◽  
Rare Lesion ◽  
Median Raphé

Median raphe cysts present anywhere between the external urethral meatus and the anus. The cysts can occur at parameatus, glans penis, penile shaft, scrotum, or perineum. Perianal region is an extremely rare location for these lesions. Here we present a 50-year-old male patient who presented with a cystic, fluctuant lesion, located at 12 o’clock in perianal region. Microscopic examination revealed a cystic lesion with keratinized and nonkeratinized stratified squamous epithelium, pseudostratified ciliated epithelium, and scattered goblet cells. The final diagnosis of the lesion was median raphe cyst. Ciliated cells and perianal localization in median raphe cysts are extremely rare characteristics.

A case of vascular leiomyoma of the larynx

1994 ◽  
Vol 108 (7) ◽  
pp. 593-595 ◽  
Author(s):  
K. Hirakawa ◽  
Y. Harada ◽  
T. Tatsukawa ◽  
A. Nagasawa ◽  
M. Fujii
Keyword(s):  
Histological Examination ◽  
Supine Position ◽  
Direct Laryngoscopy ◽  
Squamous Epithelium ◽  
Complete Removal ◽  
Normal Mucosa ◽  
General Anaesthetic ◽  
Vascular Leiomyoma ◽  
Chief Complaints ◽  
Stratified Squamous Epithelium

AbstractWe present a 68-year-old woman with a vascular leiomyoma of the larynx, a benign tumour that rarely involves that organ. Chief complaints were a feeling of a narrowing of the pharynx and difficulty in breathing in the supine position. A spherical tumour measuring 1.5 cm and covered with normal mucosa was found avthe margin of her epiglottis. The patient was administered a general anaesthetic and the tumour was successfully removed via direct laryngoscopy. Histological examination revealed that the tumour lay beneath a layer of stratified squamous epithelium and was encased in a welldefined fibrous capsule. The tumour parenchyma was composed of proliferated fibres that consisted of elongated cells, surrounded by an abundance of blood vessels. Its complete removal is the treatment of choice with care taken to avoid profuse bleeding. Recurrence is rare.

scholarly journals Microscopic Structure of the Epithelium Lining the Epiglottis in Wistar Rats

2018 ◽  
Vol 75 (1) ◽  
pp. 5
Author(s):  
Vasile RUS ◽  
Aura Ștefania PARDI ◽  
Bianca MATOSZ ◽  
Flavia RUXANDA
Keyword(s):  
Histological Examination ◽  
Wistar Rats ◽  
Squamous Epithelium ◽  
Respiratory Epithelium ◽  
Microscopic Structure ◽  
Stratified Squamous Epithelium ◽  
Keratin Layer

The aim of this study was to investigate the type of the epithelium present on the epiglottis surface, through histological examination. The epithelium lining the pharyngeal side of epiglottis is keratinized stratified squamous. The thickness of the keratin layer is different from one subject to another. Usually the keratin layer extends to the apex of the epiglottis, but in some of the animals taken into study, the keratin layer extends to the apical third of the laryngeal side of epiglottis. The epithelium lining the laryngeal side is different. In most of the epiglottises examined, the surface is lined by non-keratinized stratified squamous epithelium in the apical third. The rest of the laryngeal side of the epiglottis is lined by respiratory epithelium type. In one subject, the entire laryngeal surface is lined by a non-keratinized stratified squamous epithelium. Our study highlights that the pharyngeal side of epiglottis is lined by a keratinized stratified squamous epithelium, whereas on the laryngeal side, the epithelium in the apical third is non-keratinized stratified squamous and at the rest of the surface the epithelium is pseudostratified.

Junction of the Epithelium and Lamina Propria of the Bovine Rumen Mucosa

1967 ◽  
Vol 25 ◽  
pp. 68-69
Author(s):  
Al W. Stinson
Keyword(s):  
Osmium Tetroxide ◽  
Squamous Epithelium ◽  
Short Chain Fatty Acids ◽  
Chloride Ions ◽  
Fermentation Products ◽  
Ruminant Species ◽  
Protective Shield ◽  
Stratified Squamous Epithelium ◽  
Lead Hydroxide ◽  
Acetic Acids

The stratified squamous epithelium which lines the ruminal compartment of the bovine stomach performs at least three important functions. (1) The upper keratinized layer forms a protective shield against the rough, fibrous, constantly moving ingesta. (2) It is an organ of absorption since a number of substances are absorbed directly through the epithelium. These include short chain fatty acids, potassium, sodium and chloride ions, water, and many others. (3) The cells of the deeper layers metabolize butyric acid and to a lesser extent propionic and acetic acids which are the fermentation products of rumen digestion. Because of the functional characteristics, this epithelium is important in the digestive process of ruminant species which convert large quantities of rough, fibrous feed into energy.Tissue used in this study was obtained by biopsy through a rumen fistula from clinically healthy, yearling holstein steers. The animals had been fed a typical diet of hay and grain and the ruminal papillae were fully developed. The tissue was immediately immersed in 1% osmium tetroxide buffered to a pH of 7.4 and fixed for 2 hrs. The tissue blocks were embedded in Vestapol-W, sectioned with a Porter-Blum microtome with glass knives and stained with lead hydroxide. The sections were studied with an RCA EMU 3F electron microscope.

scholarly journals Moraxella lacunata infection accompanied by acute glomerulonephritis

Open Medicine ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 962-967
Author(s):  
Nami Sawada ◽  
Tamaki Morohashi ◽  
Tomokazu Mutoh ◽  
Tsukasa Kuwana ◽  
Junko Yamaguchi ◽  
...  
Keyword(s):  
Clinical Laboratory ◽  
Case Reports ◽  
Laboratory Data ◽  
Inflammatory Cells ◽  
Final Diagnosis ◽  
Renal Tissue ◽  
Acute Glomerulonephritis ◽  
Pathological Findings ◽  
Complement Activity ◽  
Moraxella Lacunata

AbstractMoraxella lacunata (M. lacunata) is a Gram-negative bacterium, which rarely causes serious infection. This is a rare case report of acute glomerulonephritis diagnosed by pathological findings in a child accompanied by M. lacunata infection. The patient showed hematuria, proteinuria and hyperkalemia requiring emergency hemodialysis. After hospitalization, M. lacunata bacteremia became apparent. Pathological findings showed an increase in glomerulus inflammatory cells and glomerular C3 deposition was observed in the renal tissue biopsy. Final diagnosis was endocapillary proliferative glomerulonephritis. Clinical reports of M. lacunata infection requiring emergency hemodialysis in children are rare. Previous reports have suggested that lowered immune competency with chronic kidney disease may be a risk factor associated with serious invasive cases of M. lacunata infection. However, detailed clinical laboratory data and pathological findings have not been identified in previous case reports. Our case directly indicated complement activity and acute glomerulonephritis with M. lacunata infection. Although there are various causes for acute glomerulonephritis, infection-related glomerulonephritis (IRGN) is an important concept. M. lacunata infection might have a potential risk for IRGN with dysregulation of complement activity leading to serious and invasive clinical conditions than previously considered.

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