scholarly journals Laparoscopy in diagnosis and complex treatm ent of malignant ovarian tumors

2021 ◽  
Vol 50 (1) ◽  
pp. 69-73
Author(s):  
A. A. Tsypurdeeva ◽  
A. F. Urmancheeva ◽  
D. R. Zeldovich ◽  
E. F. Kira

To study the possibilities of laparoscopy in diagnosis of malignant ovarian tumors 635 patients at different stages of the disease were examined. High informing characteristics make it possible to recommend laparoscopy as a method of improved diagnostics of tumors in smallpelvic with the aim of early revealingof malignant tumors, morphologic verification and evaluation of tumor extensiveness, diagnosis of preclinical recurrent tumors in case of diverse results of non-invasive monitoring methods.

Animals ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 186 ◽  
Author(s):  
Michael Swinbourne ◽  
David Taggart ◽  
Bertram Ostendorf

Broad-scale abundance estimates of the southern hairy-nosed wombat population use a proxy measure based on counting the number of active burrows, which is multiplied by an index of ‘wombats/active burrow’. However, the extant indices were calculated in the 1980s, prior to the use of calicivirus to control rabbits, and used invasive monitoring methods which may have affected the results. We hypothesise that the use of video might provide a logistically simple, non-invasive means of calculating updated indices. To this end, motion-activated, infra-red still and video cameras were placed at various distances outside active wombat burrows in the South Australian Murraylands and Eyre Peninsula regions. The captured imagery was inspected to determine how often the burrow was occupied by one or more wombats, and how effective the cameras were at detecting wombat activity. Video data was clearly superior to the still imagery, with more than twice as many burrow occupancies being positively identified (still: 43%). The indices of wombats/active burrow calculated based on video imagery were: Murraylands: 0.43, Eyre Peninsula: 0.42. 1948 false positive videos were recorded, of which 1674 (86%) occurred between noon and sunset.


2020 ◽  
Vol 55 (1) ◽  
pp. 32-34
Author(s):  
A. A. Arynov ◽  
N. Z. Shapatova ◽  
I. M. Smagina

Relevance: Hemodynamic disorders occupy a central position among pathological syndromes in patients receiving intensive care. Still, their diagnostics and treatment are sometimes delayed, and hemodynamic parameters and types of blood circulation are misinterpreted. This adds to the severity of such disorders and increases mortality. The purpose of the study was to analyze the diagnostics and treatment of hemodynamic disorders in cancer patients. Results: The applied methods of clinical diagnostics and non-invasive monitoring of hemodynamic parameters correlated well with invasive monitoring methods and have proven useful in the everyday practice of intensive care. Conclusion: A combination of methods of clinical diagnosis of hemodynamic disorders and with modern non-invasive methods of measuring central hemodynamics parameters allows for earlier and more accurate diagnostics and correction of hemodynamic disorders in the perioperative period in cancer patients.


2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 5053-5053
Author(s):  
Ines Vasconcelos ◽  
Sven Olek ◽  
Katharina Gellhaus ◽  
Tim Schwachula ◽  
Ioana Braicu ◽  
...  

5053 Background: Borderline ovarian tumors (BOT) are a low-grade form of ovarian malignancy with significantly less aggressive behavior than epithelial ovarian cancer (EOC). Since there is neither convincing scientific evidence nor a marker capable of predicting BOT’s behavior, we analyzed the role of immune tolerance in differential disease outcome. EOC and BOT were chosen due to similar disease etiology, despite different disease courses. Increased numbers of T-cell subpopulations infiltrate malignant tumors, so we used epigenetic tests to determine the prevalence of regulatory T-cells (Treg) and overall-T-Lymphocytes (oTL) in EOC and BOT. Methods: The ovarian cancer samples were provided by the European multicentric OVCAD study. The BOT samples were obtained from Tumor Bank Ovarian Cancer at Charité Campus Virchow (Germany). Samples and clinical data were prospectively collected and documented using validated SOPs. DNA was bisulphite-converted and forwarded to methylation-specific RT-PCR for CD3 and FOXP3 loci. Results: We evaluated 90 high-grade EOC, 12 BOT with invasive implants and 25 non-invasive BOT samples. Higher oTL-values correlate with mortality (p=0.008) and recurrence (p<0.001), while higher Treg levels correlate with recurrence (p=0.028). Patients with non-invasive BOT have lower oTL (p=0.019) and Treg (p=0.0005) levels than patients with invasive BOT and EOC, while BOT (both invasive and non-invasive) patients have lower Treg-to-oTL ratios than EOC patients (p=0.0005). Finally, oTL levels associate with overall survival in EOC (p=0.042). Conclusions: We observed a strict correlation between tumor-type, Treg and oTL levels, as well as Treg-to-oTL ratio. This is in agreement with our hypothesis that disease aggressiveness is associated with the amount tumor-infiltrating lymphocytes and may provide the explanation for differing disease courses in EOC and BOT.


2011 ◽  
Vol 4 (1) ◽  
pp. 4-14 ◽  
Author(s):  
DEBORAH J. HARVEY ◽  
COLIN J. HAWES ◽  
ALAN C. GANGE ◽  
PAUL FINCH ◽  
DAVID CHESMORE ◽  
...  

2020 ◽  
Vol 55 (1) ◽  
pp. 28-29
Author(s):  
A. A. ARYNOV ◽  
N. Z. SHAPATOVA ◽  
I. М. SMAGINA

Relevance: Hemodynamic disorders occupy a central position among pathological syndromes in patients receiving intensive care. Still, their diagnostics and treatment are sometimes delayed, and hemodynamic parameters and types of blood circulation are misinterpreted. This adds to the severity of such disorders and increases mortality. The purpose of the study was to analyze the diagnostics and treatment of hemodynamic disorders in cancer patients. Results: The applied methods of clinical diagnostics and non-invasive monitoring of hemodynamic parameters correlated well with invasive monitoring methods and have proven useful in the everyday practice of intensive care. Conclusion: A combination of methods of clinical diagnosis of hemodynamic disorders and with modern non-invasive methods of measuring central hemodynamics parameters allows for earlier and more accurate diagnostics and correction of hemodynamic disorders in the perioperative period in cancer patients.


2019 ◽  
Vol 3 (2) ◽  
pp. 130-136
Author(s):  
Arif Fadillah ◽  
Andi Friadi

Background : Malignant ovarian tumor are still the number one cause of death and the second most  of incidents for gynecological malignant tumors. The principles of management of ovarian cancer are the same as the principles of handling other malignant diseases, for the treatment of primary lesions operatively and the handling of potential sites of tumor metastases with chemotherapy. Histopathological examination is still considered a gold standard for diagnosis and definitive treatment of malignant ovarian tumors. If histopathologic results are obtained, then the patient will be planned to undergo postoperative chemotherapy. The mismatch between the preoperative and intraoperative clinical features, and the results of postoperative histopathological examination is a problem in managing cases of ovarian malignant tumors.Objective : Report a case of residive ovarian carcinoma with no appearance of malignancy marker in the previous postoperative histopathological examination.Method : Case reportCase : We report the case of a 45-year-old woman with a history of two previous laparotomy. The first operation was carried out in February 2014 on the indication of an extra ovarian cyst, resulting in the impression of a "Follicular Cysts" based on histopathological examination. The second operation was performed in March 2015, performed surgical staging tumors with an indication of malignant ovarian tumors with clinical metastases, but from histopathological examination it was found that "Cystadenoma Ovarii Muscinosum Multiloculare" and "no visible signs of malignancy", so the patient was not managed with postoperative chemotherapy. In April 2019 patients came with complaints of new mass growth, from CT-Scan and USG investigations there was a suspicious impression of a residive ovarian tumor with metastases into the omentum and massive ascites. On May 16, 2019 an optimal debulking was performed with the findings of residive mass, ascites, and mass metastases in the intra operative peritoneum. From the results of histopathological examination, it was found that "Muscinous Carcinoma with metastases to the umbilicus, peritoneum, and ascitic fluidKeywords: Malignant residive ovarian tumor, mucinous ovarian carcinoma


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