scholarly journals Etiology of epidemic encephalitis. Rosenthal (Vrach. Ob., 1922)

2021 ◽  
Vol 19 (1) ◽  
pp. 102-102
Author(s):  
V. Aristovsky

Experimental data of Levaditi, Hariver, Nicolau, Doer, Vchting, Lowenstein et al. testify according to Rosenthal that 1) virus of this disease belongs to the category of filtering; 2) by inoculation of the cerebral substance of the affected human brain (worse - cerebrospinal fluid) under the dura mater of the animal - best of all rabbit - it is possible, though not always, to cause the corresponding disease; 3) in many of its properties encephalitic virus is close to rabies virus and polymyelitis virus.

1976 ◽  
Vol 8 (2) ◽  
pp. 127-141 ◽  
Author(s):  
Remo Fumagalli ◽  
Stefano Pezzotta ◽  
Anna R. Racca ◽  
Pietro Paoletti

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Fan Jia ◽  
Li Li ◽  
Haizhou Liu ◽  
Pei Lv ◽  
Xiangwei Shi ◽  
...  

AbstractRabies virus (RV) is the most widely used vector for mapping neural circuits. Previous studies have shown that the RV glycoprotein can be a target to improve the retrograde transsynaptic tracing efficiency. However, the current versions still label only a small portion of all presynaptic neurons. Here, we reshuffled the oG sequence, a chimeric glycoprotein, with positive codon pair bias score (CPBS) based on bioinformatic analysis of mouse codon pair bias, generating ooG, a further optimized glycoprotein. Our experimental data reveal that the ooG has a higher expression level than the oG in vivo, which significantly increases the tracing efficiency by up to 12.6 and 62.1-fold compared to oG and B19G, respectively. The new tool can be used for labeling neural circuits Therefore, the approach reported here provides a convenient, efficient and universal strategy to improve protein expression for various application scenarios such as trans-synaptic tracing efficiency, cell engineering, and vaccine and oncolytic virus designs.


2013 ◽  
Vol 171 (1) ◽  
pp. 198-208 ◽  
Author(s):  
Sandip Kumar Dash ◽  
Minakshi Sharma ◽  
Shashi Khare ◽  
Ashok Kumar

Sign in / Sign up

Export Citation Format

Share Document