scholarly journals A trial of the use of perfusion computed tomography of the brain in combination with transcranial Doppler ultrasonography of blood vessels in patients with acute cerebrovascular accident

2020 ◽  
Vol 101 (1) ◽  
pp. 124-131
Author(s):  
K G Valeeva ◽  
S K Perminova ◽  
A Ya Nazipova ◽  
S V Kurochkin ◽  
A A Yakupova

Aim. Assessment of cerebral blood flow in various vascular beds in patients with an acute cerebrovascular accident in the acute period by perfusion computed tomography in combination with transcranial Doppler ultrasonography of cerebral vessels. Methods. Data was analyzed from perfusion computed tomography of the brain and transcranial Doppler ultrasonography in 35 patients with an acute cerebrovascular accident, based at the vascular centre of the City Clinical Hospital No. 7 of Kazan. The study included 18 (51.4%) women and 17 (48.6%) men who had arrived in the first hours after a vascular accident. When analyzing the stroke subtype, atherothrombotic subtype was determined in 27 (77.1%) patients, cardioembolic subtype in 5 (14.3%) patients, and 3 (8.6%) patients had had a transient ischemic attack. Results. Perfusion computed tomography is a method that allowed evaluation of the structure of the brain, and blood supply to the anterior cerebral (in 2.9% of the studied patients), middle cerebral (in 62.9% of the studied patients), posterior cerebral (in 11.4% of the studied patients) and vertebral (in 14.2% of the studied patients) arteries of patients with a stroke. The method revealed a zone of critical perfusion (ischemic penumbra) by quantitatively processing perfusion indicators in the anterior cerebral blood flow system (decrease in rate and increase in average volume of cerebral blood flow and average transit time) and in the posterior cerebral circulation system (decrease in blood flow and prolongation of transit time) in the bed of the right vertebral artery). The method also aided the construction of perfusion maps. Transcranial Doppler ultrasonography of cerebral vessels revealed breaches in the cerebral circulation: a decrease in the linear velocity of blood flow in the right middle cerebral arterial bed and in the posterior circulatory system of blood flow in the brain, and an increase in the pulsatility index in all the studied vascular beds. Conclusion. Perfusion computed tomography of the brain in combination with transcranial Doppler ultrasonography is applicable to patients with stroke in various vascular beds, followed by determination of indications for thrombolytic therapy and thrombectomy.

Neurosonology ◽  
1997 ◽  
Vol 10 (3) ◽  
pp. 96-101
Author(s):  
Kensaku TAKASE ◽  
Michiharu KASHIHARA ◽  
Atsuhiko SUZUE ◽  
Osamu TAKIMOTO ◽  
Tsuneyo HASHIMOTO

2015 ◽  
Vol 9 (4) ◽  
pp. 0-0
Author(s):  
Сеинова ◽  
L. Seinova

Currently a problem of timely diagnostics and treatment of disorders of cerebral circulation is one of the most important for medicine, as strokes and chronic brain ischemia occupy a significant place among the diseases leading to mortality and disability of population. Computed tomography is one of the leading diagnostics of cerebro-vascular disorders. Today, the diagnostic capabilities of perfusion computed tomography, especially in the field of subtle changes in perfusion in infected and in the contralateral hemispheres of the brain are poorly understood and aren’t used in full. The relevance and scientific novelty of this research is not in doubt. Based on the data of 87 patients with ischemic infarction of the cerebral hemispheres of the brain and vascular encephalopathy, a comparative analysis of blood flow in the affected and contralateral hemispheres, was carried out. The degree of asymmetry of blood flow depending on the phase of development of ischemic stroke and chronic brain ischemia was evaluated. The studies have shown that the relative indicator of inter-hemispheric asymmetry is reduced in the course of development of cerebral infarction, reaching minimum values of dyscirculatory encephalopathy. The author substantiates the practical use of the proposed indicator of inter-hemispheric asymmetry in the evaluation of the degree of chronic ischemic disturbances of cerebral blood flow.


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