scholarly journals S. Sukhanov. The pathological anatomy of the nerve cell in relation to varicose atrophy of the dendrites of the cerebral cortex. Extract from the Journal "La Cellule" t. XIV, 2nd fascicle

2020 ◽  
Vol VII (1) ◽  
pp. 183
Author(s):  
A. Yanishevskiy

In this article, the author has applied the Golgi method for studying changes in the cells of the cerebral cortex in case of poisoning with arsenic, in case of infection with canine rabies, in case of poisoning with teberculin and in thyroidectomy.




Author(s):  
T. Sh. Morgoshiia ◽  
N. A. Syroezhin

The main milestones of the life and work of L.O. Darkshevich. It is noted that the work of a professor on the study of the pathology of muscles and peripheral nerves is of great interest. As early as 1903, in a German manual on pathological anatomy of the nervous system, Liverius Osipovich wrote a chapter on the pathological anatomy of muscles. We emphasize that later they wrote several articles on cerebral and arthropathic amiotrophies. Studying the question of the so-called retrograde degeneration of nerves, he pointed to the development of degenerative changes not only in the peripheral, but also in the central segment of the nerve, which is of great interest for clarifying the spread of the process. The article notes that Liveriy Osipovich Darkshevich considered the creation of a manual on nervous diseases as the greatest debt of his life, which was the testament of his late teacher — Professor A.Ya. Kozhevnikov, who had not managed to do this. Well aware of the conditioned reflex principles of the central nervous system, Liverii Osipovich attached special importance to the cerebral cortex as a body of mental activity. He pointed out that normal mental activity is formed under the influence of incessantly arriving stimuli of the external world, which, having reached the cerebral cortex and entering our consciousness, give rise to representations, the appearance of which in turn gives rise to the manifestation of active cortical activity-the emergence of volitional impulses. Liverii Osipovich was an ardent supporter of active disease therapy and was often an innovator in this field.



1947 ◽  
Vol 93 (391) ◽  
pp. 262-272 ◽  
Author(s):  
S. Davidenkov

The theory concerning the various types of nervous system in man, generally acknowledged by Russian neurologists, is based on the principles established by Pavlov in his investigations on conditioned reflexes in dogs. It was Pavlov and his collaborators who succeeded in establishing that all variations in the nervous types of dog are due to three main differences. These differences may consist in varying intensity in the essential processes (excitation and inhibition), peculiar to the nerve cell of the cerebral cortex, with the result that some specimens are of a stronger, others of a weaker nervous type. There may also be differences in the degree of equilibrium attained between the two processes, with the result that some specimens are well balanced, while others are unbalanced. Finally the differences may consist in the rate at which the nerve cell is able to pass from one state to the other, in the rate at which the concentration of the excitation or inhibition process is reached after the primary phase of irradiation, and in the rate at which the excitation process becomes extinct within a cell after the action of the stimulus has ceased. As a result of these latter differences some specimens may be more mobile, others more inert. At the same time it was established that the differences with respect to all these three functions could develop independently of one another, owing to which fact the resulting typologic combinations are extremely varied.



1903 ◽  
Vol 3 (3-4) ◽  
pp. 149-150
Author(s):  
A. L. Lyubushin

Journal of neuropathology and psychiatry named after S. S. Korsakov, book. 1 and 2 1902The study of the literature on this issue (Kahlbaum, Kiernan, Chizh, Alzheimer) leads to the conclusion that the evidence on the pathological anatomy of early dementia is extremely inadequate and unclear. The author introduces the history of illness to two patients who suffered from early dementia. Both cases ended in death; at autopsy with microscopic examination, they appeared on the face: in one case, the brain was full-blooded, slightly swollen, atrophy of the gyrus of the brain and atrophy of the cortical layer, expressed equally in all lobes of the brain. The lateral ventricles are slightly distended and contain a significant amount of fluid; in another - leptomeningitis sclerotica, Atrophia



1904 ◽  
Vol 4 (7-8) ◽  
pp. 400-402
Author(s):  
Н. Carrier

Abstracts Psychiatry.The contents of this work have been transferred by I. Vueer in the bibliography section of the May book "Arch, de Neurol." for the present year. N. Sagieg examines various psychopathic states in connection with the available data of pathological anatomy, the first part of the work, the author will devote to a critical assessment of the facts concerning the normal and pathological histology of the nerve cell, stopping attention on the Niss Nevsky parts belonging to the to the question of the time of the appearance in the nerve centers of true cadaveric changes and, finally, to the method of preparation of the preparations.



The termination of fibres from the cerebral cortex and thalamus upon the dendritic spines of the medium spiny cell of the caudate nucleus has been studied with the Golgi method. Lesions were placed in the cerebral cortex, thalamus or cerebral cortex and thalamus of adult cats and kittens. After survival periods of between 6 and 52 weeks the animals were perfused with a mixture of formaldehyde and glutaraldehyde and the caudate nuclei impregnated by a Golgi technique. The distribution of spines along the dendrites of the medium spiny cell was determined in normal material by counting them over 20 /xm lengths of the dendrites, and was compared with their number and distribution after the various lesions. The density of spines on the dendrites varies with the distance from the cell body. The first 20 /xm length of dendrite is spine free, but thereafter the number increases to a peak between 60 and 80 /xm from the cell body after which the number per 20 /xm length decreases. The distribution pattern does not alter after any of the lesions, although the overall number of spines decreases. The decrease after lesions in the cerebral cortex or thalamus is the same, and after a combined lesion of thalamus and cortex is twice as great indicating that the fibres from both these regions end upon spines of the same cells. Statistical analysis shows that these results are significant.









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