scholarly journals Anatomic features of anterior chamber angle in children with glaucoma depending on the degree of the cicatricial retinopathy of prematurity

2019 ◽  
Vol 12 (1) ◽  
pp. 21-26
Author(s):  
Maria A. Makarova ◽  
Viktoria M. Panchishena ◽  
Elena V. Brusakova ◽  
Regina V. Ershova ◽  
Elvira I. Saidasheva ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Retinopathy Of Prematurity ◽  
Full Term ◽  
Congenital Glaucoma ◽  
Control Group ◽  
Study Group ◽  
Anterior Chamber Angle ◽  
Anatomic Structure ◽  
Preterm Children ◽  
Chamber Angle

Introduction. The retinopathy of prematurity (ROP) is a leading condition in the nosological structure of ophthalmic pathology in preterm children. A number of researchers note the increase in frequency of glaucoma development in such patients, considerably worsening the prognosis of the disease. At the same time, features of ocular hydrostatics and hydrodynamics taking into account the immaturity of the eye are studied insufficiently. The purpose of the study was to estimate the anterior chamber angle anatomy in preterm children with glaucoma depending on the cicatricial ROP severity. Materials and methods. The study group included 45 preterm children (87 eyes) aged from 6 months to 18 years with glaucoma on the background of cicatricial ROP. The control group consisted of 27 full-term children (54 eyes) with congenital glaucoma. As an addition to traditional ophthalmologic examination, iridocorneal goniography using a pediatric retinal camera was performed. Results. In children of the study group, anomalies of anterior chamber angle anatomic structure were diagnosed in the absolute majority of cases 97.7% of cases (85 eyes) and depended on the cicatricial ROP severity: at degrees 1-3 they were similar to those in congenital glaucoma in full-term children; at degrees 4-5 glaucoma was of secondary nature and developed as a result of a combination of dysgenesis signs in the anterior chamber angle. Conclusion. Cicatricial ROP of any degree is a high risk factor for the development of secondary glaucoma.

scholarly journals THE HISTOLOGICAL STUDY OF THE STRUCTURES OF THE ANTERIOR CHAMBER ANGLE IN THE CHILDREN OF DIFFERENT GESTATIONAL AGE UNDER THE NORMAL CONDITIONS AND IN THE PRESENCE OF CONGENITAL GLAUCOMA

2017 ◽  
Vol 12 (2) ◽  
pp. 87-90
Author(s):  
Marina Andreevna Zertsalova ◽  
E. P Fedotova ◽  
V. V Brzheskiy ◽  
R. A Nasirov
Keyword(s):  
Anterior Chamber ◽  
Gestational Age ◽  
Trabecular Meshwork ◽  
Histological Study ◽  
Full Term ◽  
Fibrous Membrane ◽  
Congenital Glaucoma ◽  
Anterior Chamber Angle ◽  
Histological Picture ◽  
Chamber Angle

Purpose. The objective of the present study was to obtain and investigate the tissue samples taken from the anterior chamber angle of the children of different gestational age under the normal conditions and in the presence of congenital glaucoma; the secondary objective was to carry out the histological study of the pieces of tissues removed from the glaucoma patients of different gestational age undergoing hypotensive filtration surgery (sinusotrabeculectomy). Materials and methods. The anterior chamber angle histological preparations from a total of five enucleated eyes were available for the intravital investigation of the trabecular meshwork (two of them were obtained from the full-term infants and one from a premature baby). Results. The histological study of the structures of the anterior chamber angle of the enucleated eyes has demonstrated the presence in all the cases of cornea, Descemet’s membrane, trabecular meshwork, Schlemm’s canal, and iris. The morphological structure of the anterior chamber angle associated with congenital glaucoma shows up some peculiar features compared with the normal one, such as its block by the permanent fibrous membrane which penetrates deep into the trabecular meshwork that, in its turn, is formed from the rough and thickened tissue. The histological picture of the fetal eye at different gestational age exhibits the open anterior chamber angle, the well developed porous trabecular meshwork, and fragmentation of Descemet’s membrane near the trabecular meshwork. No signs of fibrous degeneration of the trabecule have been apparent. Conclusion. The intravital investigation of the trabecular meshwork has demonstrated some peculiar features that differ depending on the gestational age in birth. In the full-term babies, it is hypoplastic and covered with the rough fibrous membrane at certain places. Its histological picture is similar to that of the preparations of the enucleated eyes. In the premature babies, the trabecular meshwork is fibrous and characterized by enhanced cellularity; it undergoes fibrous degeneration that becomes apparent after the birth of the premature child (it is supposed to be related to the proliferative processes inherent in such babies).

Anterior Chamber Angle and Anterior Segment Structure of Eyes in Children With Early Stages of Retinopathy of Prematurity

2017 ◽  
Vol 179 ◽  
pp. 46-54 ◽  
Author(s):  
Shirley H.L. Chang ◽  
Yung-Sung Lee ◽  
Shiu-Chen Wu ◽  
Lai-Chu See ◽  
Chia-Chi Chung ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Retinopathy Of Prematurity ◽  
Anterior Segment ◽  
Anterior Chamber Angle ◽  
Early Stages ◽  
Chamber Angle

scholarly journals CHARGE association with congenital glaucoma due to maldevelopment of the anterior chamber angle

2009 ◽  
Vol 75 (3) ◽  
pp. 322-324 ◽  
Author(s):  
Naomichi Katai ◽  
Yoshio Urakawa ◽  
Yukio Sato ◽  
Kazuto Miyanaga ◽  
Katsuzo Segawa ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Congenital Glaucoma ◽  
Anterior Chamber Angle ◽  
Charge Association ◽  
Chamber Angle

scholarly journals Comparative assessment of different methods of congenital glaucoma surgical treatment considering patient’s age

2013 ◽  
Vol 94 (6) ◽  
pp. 847-850
Author(s):  
T K Toykuliev
Keyword(s):  
Surgical Treatment ◽  
Anterior Chamber ◽  
Antihypertensive Effect ◽  
Age Groups ◽  
Comparative Assessment ◽  
Congenital Glaucoma ◽  
Anterior Chamber Angle ◽  
Application Methods ◽  
Trabeculotomy Ab Externo ◽  
Chamber Angle

Aim. To study the effectiveness of antihypertensive operations of trabeculotomy ab externo and sinus trabeculoectomy in our modification in patients with congenital glaucoma and to justify its application. Methods. The following surgeries were performed: trabeculotomy ab externo - on 57 eyes of 51 patients, sinus trabeculoectomy - on 46 eyes of 42 children, classic trabeculoectomy - on 23 eyes of 19 patients, and trabeculoectomy with elements of intrascleral autodrainage in our modification - on 23 eyes of 23 patients. Among them, 22 patients were younger than 1 month, aged from 1 to 6 months - 30, from 6 months to 1 year - 18, from 1 to 3 years - 15 and from 3 to 5 years old - 8 patients. Results. Long-lasting hypotension was achieved in 86.95% of patients after sinus trabeculoectomy, in 80.39% of patients after trabeculotomy ab externo. The best results were obtained in patients younger than 6 months. In the older age groups, antihypertensive effect of trabeculotomy ab externo markedly decreased and was only 50% at the age of 3-5 years. The results after sinus trabeculoectomy were comparable in all age groups. Conclusions. Trabeculotomy ab externo can be recommended as an operation of choice during the first months of life in congenital glaucoma patients, based on the characteristics of the anterior chamber angle.

Optical coherence tomography of the anterior chamber angle in children with congenital glaucoma and glaucoma secondary to retinopathy of premature

2020 ◽  
pp. 17-18
Author(s):  
A.I. Baranov ◽  
◽  
М.A. Zertcalova ◽  
V.V. Brzheskii ◽  
N.N. Sadovnikova ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Chamber ◽  
Congenital Glaucoma ◽  
Optical Coherence ◽  
Anterior Chamber Angle ◽  
Chamber Angle

Актуальность. Изменения угла передней камеры (УПК) играют ведущую роль в этиопатогенезе как врожденной глаукомы, так и глаукомы на фоне ретинопатии недоношенных (РН). Исследование параметров УПК у таких детей при помощи современных методов визуализации является актуальной задачей современной офтальмологии. Цель. Исследование УПК у детей с врожденной глаукомой и глаукомой, протекающей на фоне РН различных стадий, при помощи оптического когерентного томографа. Материал и методы. Обследованы 28 детей (33 глаза), среди которых 5 (7 глаз) – с врожденной глаукомой и 23 (26) – с глаукомой на фоне рубцового периода РН. РН II стадии была выявлена у 5 детей (7 глаз), III стадии – у 11 (11) и 7 детей (8 глаз) наблюдались с РН IVа стадии. Всем детям проводили исследование УПК с помощью оптического когерентного томографа Carl Zeiss Cirrus HD-OCT 5000 с использованием внешней линзы передней камеры. Оценивали ширину УПК и дистанцию трабекула-радужка (ДТР). Результаты. В группе детей с врожденной глаукомой средняя ширина УПК составила 47,29±11,93°, средняя ДТР – 607,14±117,57 мкм. У детей с глаукомой на фоне РН данные параметры составили, в среднем, 41,04±10,64° и 470,77±139,11 мкм соответственно. При этом наименьшие значения ширины УПК и ДТР были выявлены в группе детей с IVа стадией РН и составили 30,25±12,33° и 350±105,02 мкм. Выводы. В группе детей с глаукомой на фоне ретинопатии недоношенных отмечается уменьшение ширины УПК и дистанции трабекула-радужка по сравнению с детьми с врожденной глаукомой. Данная тенденция наиболее выражена в группе детей с IVа стадией РН, что, вероятно, обусловлено деформацией УПК в ходе выраженного экстраретинального пролиферативного процесса.

scholarly journals Evaluation of Anterior Chamber Depth and Anterior Chamber Angle Changing After Phacoemulsification in the Primary Angle Close Suspect Eyes

2019 ◽  
Vol 7 (24) ◽  
pp. 4297-4300
Author(s):  
Anh Tuan Vu ◽  
Van Anh Bui ◽  
Hai Long Vu ◽  
Do Quyet ◽  
Than Van Thai ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Intraocular Lens ◽  
Anterior Chamber Depth ◽  
Angle Closure ◽  
Control Group ◽  
Anterior Chamber Angle ◽  
Interventional Study ◽  
Primary Angle Closure ◽  
Shallow Anterior Chamber ◽  
Chamber Angle

BACKGROUND: Phacoemulsification surgery has the ability to deeply alter the segment anterior morphology, especially in eye with shallow anterior chamber (AC), narrow anterior chamber angle (ACA). However, the changes of anterior chamber depth (ACD) and ACA on the close angle suspect eyes after phacoemulsification have not been mentioned in many studies. So, we conduct this research. AIM: To evaluate the alteration in the ACA and ACD after phacoemulsification in the close angle suspect eyes. METHODS: Interventional study with no control group. Subjects were the primary angle closure suspect (PACS) eyes, that were operated by phacoemulsification with intraocular lens (IOL) at Glaucoma Department of VNIO from December 2017 to October 2018. RESULTS: 29 PACS eyes with cataract were operated by phacoemulsification with intraocular lens. After 3 months of monitoring, the average ACD augmented from 2.082 ± 0.244 to 3.673 ± 0.222 mm. AOD500 increase from 0.183 ± 0.088 to 0.388 ± 0.132 μm, AOD750 increased from 0.278 ± 0.105 to 0.576 ± 0.149 μm. The TISA500 enlarged from 0.068 ± 0.033 to 0.140 ± 0.052 mm2, TISA750 enlarged from 0.125 ± 0.052 to 0.256 ± 0.089 mm2 at the third month (p < 0.01). CONCLUSION: Phacoemulsification surgery increases the ACD and enlarged the angle in the PACS eyes.

scholarly journals The Relationship between Anterior Chamber Angle and Intraocular Pressure Early after V4c Implantable Collamer Lens Implantation

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Zongli Hu ◽  
Chunlin Chen ◽  
Min Sun ◽  
Rongdi Yuan ◽  
Jian Ye
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Linear Correlation ◽  
Control Group ◽  
Anterior Chamber Angle ◽  
Implantable Collamer Lens ◽  
Significant Difference ◽  
The Right ◽  
The Relationship ◽  
Chamber Angle

Purpose. To confirm the relationship between anterior chamber angle (ACA) and intraocular pressure (IOP) early after V4c implantable collamer lens (ICL) implantation. Methods. Patients were assigned to two groups: (1) right eyes (control group) and (2) left eyes (experimental group), with miosis conducted immediately after ICL implantation in the left eyes. IOP, angle opening distance (AOD), trabecular-iris angle (TIA), and pupil diameter (PD) were compared between two groups at postoperative hours 1, 2, and 24. The relationship between ACA, PD, and IOP was analyzed by multiple linear regression. Result. Thirty-six eyes of 18 patients were enrolled. The prevalence of ocular hypertension (OHT, defined as IOP ≥ 21 mmHg) was 61.11% and 16.67% in the right and left eyes, respectively, (χ2 = 7.481, p=0.006). At postoperative hours 1 and 2, IOP and PD were significantly higher p<0.001 in the right eyes, and TIA and AOD were significantly lower p<0.05 in the right eyes than in the left eyes. There was no significant difference at 24 h postoperative in these parameters. After the right eye ICL implantation, the changes of AOD 500 and PD were both linearly correlated with postoperative IOP change (β = −23.707 and 1.731, respectively; p = 0.013 and 0.002, respectively). Conclusion. The ACA was significantly narrowed immediately after V4c ICL implantation. There was a negative linear correlation between ACA and early IOP and a positive linear correlation between PD and early IOP. We recommend the use of intracameral miotics immediately after V4c ICL implantation to reduce the incidence of IOP spikes.

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