scholarly journals Hemodynamic Patterns Determined By Non-Invasive Cw-Doppler Ultrasound Cardiac Monitoring (USCOM) in Preterm Neonates with Respiratory Distress Syndrome During Non-Invasive Respiratory Support

2017 ◽  
Vol 8 (3) ◽  
pp. 41-46
Author(s):  
Vera A. Sergeeva ◽  
Yuri S. Alexandrovich ◽  
Denis M. Strelkov ◽  
Kseniya A. Siniuk
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Diastolic Dysfunction ◽  
Doppler Ultrasound ◽  
Distress Syndrome ◽  
Respiratory Support ◽  
Preterm Neonates ◽  
Term Neonates ◽  
Non Invasive ◽  
Bedside Method

Aim: To determine the hemodynamic patterns in preterm neonates with respiratory distress syndrome (RDS) using the USCOM-1A technology. Materials and Methods: The USCOM device is a bedside method of evaluating cardiac output (CO) based on continuous-wave Doppler ultrasound. Hemodynamic parameters were measured daily for 7 days in 32 preterm neonates 32 ± 1 weeks of gestation (1688 ± 111 g) with RDS requiring noninvasive respiratory support (NCPAP, NIPPV, HFNC) and no catecholamine support in comparison with 28 healthy term neonates (3100 ± 690 g). Results: At day 1, preterm neonates had lower SVI (18 ± 5 vs 28 ± 8 ml m-2, p = 0.043) and higher SVRI (1585 ± 245 vs 1035 ± 358 dyn s cm-5 m2, p = 0.013) with a tendency for lower cardiac index (2.6 ± 0.8 vs 4.0 ± 1.3 l min-1 m-2, p = 0.089). Together with no difference in SMII, it indicates the presence of diastolic dysfunction with low preload. It is noted that all parameters had not changed by day 7 in preterm neonates, whereas term neonates demonstrated significantly increased SMII reflecting postnatal cardiovascular adaptation. Compared with preterm neonates with RDS requiring NCPAP/NIPPV, preterm neonates requiring HFNC had higher levels of FTc (330 ± 59 vs 388 ± 41 ms, р = 0.045), SVI (13 ± 3 vs 18 ± 4, ml/m2, р = 0.007), SMII (0.41 ± 0.09 vs 0.57 ± 0.21, р = 0.02), and CI (2.2 ± 0.6 vs 4.5 ± 0.9 l/min/m2, р = 0.006). Conclusions:Noninvasive respiratory support in preterm neonates with RDS may lead to diastolic dysfunction that is less prominent in neonates with HFNC.

USE OF EARLY NASAL CONTINUOUS POSITIVE AIRWAY PRESSURE IN TREATMENT OF PRETERM NEONATES WITH HYALINE MEMBRANE DISEASE (NEONATAL RESPIRATORY DISTRESS SYNDROME)

2021 ◽  
pp. 15-17
Author(s):  
Ranjeet Kumar ◽  
Aarti Sharma ◽  
Falak Naaz ◽  
Zeeshan Ahmed
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Severe Disease ◽  
Effective Means ◽  
Neonatal Respiratory Distress Syndrome ◽  
Respiratory Support ◽  
Preterm Neonates ◽  
Antenatal Steroids ◽  
Neonatal Respiratory Distress

Objective:To evaluate the outcome of early nasal CPAPin premature neonates with neonatal respiratory distress syndrome. Methods: 100 babies of 28-34 weeks gestational age admitted in Neonatal ICU of Nalanda Medical College & Hospital, Patna (Bihar, India), with clinical diagnosis of HMD, requiring respiratory support were treated with early nasal CPAPand studied prospectively from 1st November 2014 to 31st October 2016. Results: We found a success rate of 80% in babies with HMD, who were managed with early nasal CPAPalone. Remaining 20% needed intubation and higher mode of ventilation. Mild and moderate grade HMD were effectively managed with early nasal CPAP (P<0.05). It was also found to be effective in babies of mothers who have received antenatal steroids (P<0.05). Conclusion: Prematurity is the commonest predisposing cause for HMD. Early nasal CPAPis safe, inexpensive and effective means of respiratory support in HMD. It is useful in mild and moderate grade disease. It may not be a replacement for assisted ventilation in severe disease. It is also found to be more effective in babies of mothers who have received antenatal steroids.

scholarly journals Diagnosis and Management of Acute Respiratory Distress Syndrome in a Time of COVID-19

Diagnostics ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1053
Author(s):  
Shayan Kassirian ◽  
Ravi Taneja ◽  
Sanjay Mehta
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Failure ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Clinical Outcomes ◽  
Distress Syndrome ◽  
Respiratory Support ◽  
Hypoxemic Respiratory Failure ◽  
Non Invasive ◽  
The Right

Acute respiratory distress syndrome (ARDS) remains a serious illness with significant morbidity and mortality, characterized by hypoxemic respiratory failure most commonly due to pneumonia, sepsis, and aspiration. Early and accurate diagnosis of ARDS depends upon clinical suspicion and chest imaging. Coronavirus disease 2019 (COVID-19) is an important novel cause of ARDS with a distinct time course, imaging and laboratory features from the time of SARS-CoV-2 infection to hypoxemic respiratory failure, which may allow diagnosis and management prior to or at earlier stages of ARDS. Treatment of ARDS remains largely supportive, and consists of incremental respiratory support (high flow nasal oxygen, non-invasive respiratory support, and invasive mechanical ventilation), and avoidance of iatrogenic complications, all of which improve clinical outcomes. COVID-19-associated ARDS is largely similar to other causes of ARDS with respect to pathology and respiratory physiology, and as such, COVID-19 patients with hypoxemic respiratory failure should typically be managed as other patients with ARDS. Non-invasive respiratory support may be beneficial in avoiding intubation in COVID-19 respiratory failure including mild ARDS, especially under conditions of resource constraints or to avoid overwhelming critical care resources. Compared to other causes of ARDS, medical therapies may improve outcomes in COVID-19-associated ARDS, such as dexamethasone and remdesivir. Future improved clinical outcomes in ARDS of all causes depends upon individual patient physiological and biological endotyping in order to improve accuracy and timeliness of diagnosis as well as optimal targeting of future therapies in the right patient at the right time in their disease.

scholarly journals Advanced approaches in the treatment of neonatal respiratory distress syndrome using non-invasive respiratory support

2020 ◽  
Vol 17 (5) ◽  
pp. 71-79
Author(s):  
V. E. Ryumin ◽  
S. V. Kinzhalova ◽  
G. N. Chistyakova ◽  
I. I. Remizova ◽  
K. P. Shakirova
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Very Low Birth Weight ◽  
Lung Ventilation ◽  
Respiratory Support ◽  
Non Invasive ◽  
Modern Methods ◽  
Neonatal Respiratory Distress ◽  
Specialized Equipment

The article analyzes literature data on modern methods of non-invasive respiratory support for premature newborns with respiratory distress syndrome. The article describes positive and negative aspects of the contemporary methods and devices of non-invasive lung ventilation widely used as a starting method of respiratory therapy in obstetrics units of any level, including children with extremely and very low birth weight. The choice of the device and management tactics often depends on the facilities and financial situation of medical units as well as on the experience of medical professionals using specialized equipment.

scholarly journals Effect of Surfactant therapy on clinical outcome of Respiratory Distress Syndrome in premature neonates at French Medical Institute for Mother and Children

2020 ◽  
Vol 5 (1) ◽  
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Hyaline Membrane Disease ◽  
Preterm Neonates ◽  
Medical Institute ◽  
Term Neonates ◽  
Premature Babies ◽  
Healthy Infants

Respiratory distress syndrome (RDS) of the newborn, also known as Hyaline Membrane Disease, is a breathing disorder of premature babies. In healthy infants, the alveoli—the small, air-exchanging sacs of the lungs—are coated by surfactant, which is a soap-like material produced in the lungs as the fetus matures in preparation for birth. If premature newborns have not yet produced enough surfactant, they are unable to open their lungs fully to breathe. As the efforts, our hospital is to deliver health services in a best manner to have high quality of service delivery and a low number of mortality, although the RDS is high in Afghanistan, and there is no any reliable data, which show major causes death during in-bed hospitalization. Gradually increment of mortality rate of Respiratory Distress Syndrome at French Medical Institute for Mother and Children, based on observational and unreliable accurate data, is higher among preterm neonates versus term neonates. We are going to have a retrospective study, which will be the first study in Afghanistan in such area.

scholarly journals Development and validation of a point-of-care breath test for octane detection

The Analyst ◽  
2021 ◽  
Author(s):  
Laura Anna Hagens ◽  
Alwin RM Verschueren ◽  
Ariana Lammers ◽  
Nanon F.L. Heijnen ◽  
Marry R Smit ◽  
...  
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Breath Test ◽  
Distress Syndrome ◽  
Point Of Care ◽  
Non Invasive ◽  
Bedside Method ◽  
Development And Validation

Background There is a demand for a non-invasive bedside method to diagnose Acute Respiratory Distress Syndrome (ARDS). Octane was discovered and validated as the most important breath biomarker for diagnosis...

Study of Respiratory Distress Syndrome (RDS) in preterm neonates

2012 ◽  
Vol 3 (2) ◽  
pp. 218-220
Author(s):  
PANKTI D DESAI ◽  
◽  
HETAL D VORA ◽  
S H MANSURI S H MANSURI
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Preterm Neonates
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