scholarly journals Comparative estimation vassseland hepatoprotective properties galenic plant drugs of 16 Caragana Lam. species

2018 ◽  
Vol 16 (3) ◽  
pp. 60-67
Author(s):  
Oleg D. Barnaulov ◽  
Galina A. Belodubrovskaya

According to reductions traditional Chinese and Tibetian medicines Caragana Lam. species are using for treating patients with a lot of diseases including vascular and hepatobiliary pathology. Substantiation such using are confirmed experimentaly. Decoctions overground parts 13 from investigated 16 Caragana species demonstrated hepatoprotective properties keeping detoxycal liver function of mice after injection CCL4 and 8 of them prevented the losing glycogen concentration in liver. Vessel protective properties were demonstrated by 12 decoctions and 15 etanol tincturеs caragana species.

Author(s):  
S.S. Poolsawat ◽  
C.A. Huerta ◽  
S.TY. Lae ◽  
G.A. Miranda

Introduction. Experimental induction of altered histology by chemical toxins is of particular importance if its outcome resembles histopathological phenomena. Hepatotoxic drugs and chemicals are agents that can be converted by the liver into various metabolites which consequently evoke toxic responses. Very often, these drugs are intentionally administered to resolve an illness unrelated to liver function. Because of hepatic detoxification, the resulting metabolites are suggested to be integrated into the macromolecular processes of liver function and cause an array of cellular and tissue alterations, such as increased cytoplasmic lysis, centrilobular and localized necroses, chronic inflammation and “foam cell” proliferation of the hepatic sinusoids (1-4).Most experimentally drug-induced toxicity studies have concentrated primarily on the hepatic response, frequently overlooking other physiological phenomena which are directly related to liver function. Categorically, many studies have been short-term effect investigations which seldom have followed up the complications to other tissues and organs when the liver has failed to function normally.


1953 ◽  
Vol 25 (4) ◽  
pp. 548-552 ◽  
Author(s):  
Thomas J. Rankin ◽  
Robert L. Jenson ◽  
Mahlon Delp

JAMA ◽  
1965 ◽  
Vol 194 (8) ◽  
pp. 933-933
Author(s):  
H. B. Eisenstadt

2014 ◽  
Vol 52 (08) ◽  
Author(s):  
KC Grotemeyer ◽  
H Wilkens ◽  
F Lammert ◽  
R Bals ◽  
R Kaiser

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