In Vivo Performance of the Femoral Head-Neck Taper Connection and Development of an Electrochemical Framework for Quantitative Corrosion Investigations

2021 ◽  
Author(s):  
Genymphas Higgs
Keyword(s):  
Author(s):  
R. W. Colbrunn ◽  
J. J. Bottros ◽  
C. B. Greeson ◽  
A. van den Bogert ◽  
W. K. Barsoum

Hip dislocation often results from neck impingement and subsequent subluxation. Having a model to study impingent-free range of motion (ROM) and dislocation potential at the impingement postures can elucidate the contribution to joint stability of prosthetic design, component position, anatomical variables, and biomechanical factors. Much controversy surrounds the resurgence of femoral head resurfacing (FHR) and its biomechanical implications of retaining the femoral neck, particularly its head-neck ratio. We have developed a dynamic cadaveric robotics model that functions in real time under load-control parameters to recreate in vivo hip mechanics. This study specifically identifies and compares the impingent-free ROM and a stability index value that quantifies the dislocation potential in the native hip, femoral head resurfacing and total hip replacement (size 28, 36mm femoral heads).


2008 ◽  
Vol 467 (3) ◽  
pp. 651-659 ◽  
Author(s):  
Marcel Dudda ◽  
Christoph Albers ◽  
Tallal Charles Mamisch ◽  
Stefan Werlen ◽  
Martin Beck
Keyword(s):  

2002 ◽  
Vol 84-B (4) ◽  
pp. 556-560 ◽  
Author(s):  
H. P. Nötzli ◽  
T. F. Wyss ◽  
C. H. Stoecklin ◽  
M. R. Schmid ◽  
K. Treiber ◽  
...  
Keyword(s):  

2018 ◽  
Vol 29 (6) ◽  
pp. 647-651 ◽  
Author(s):  
Giuseppe Valente ◽  
Brent Lanting ◽  
Steven MacDonald ◽  
Matthew G Teeter ◽  
Douglas Van Citters ◽  
...  

Introduction:Material loss at the head-neck junction in total hip arthroplasty may cause adverse clinical symptoms and implant failure. The purpose of this study was to quantitatively examine the effects of head size, stem material and stem offset on material loss of the head-neck taper interface of a single trunnion design in retrieval implants of metal on polyethylene bearing surfaces.Methods:A retrieval study was performed to identify all 28-mm and 32-mm femoral heads from a single implant/taper design implanted for >2 years. This included n = 56 of the 28-mm heads and n = 23 of the 32-mm heads. The 28-mm femoral heads were matched to 32-mm femoral heads based on time in vivo and head length. A coordinate measuring machine was used to determine maximum linear corrosion depth (MLD). Differences in MLD for head diameter, stem material, and stem offset were determined.Results:There were no differences between groups for age, gender, BMI, or implantation time. There was no difference in MLD between 28 mm and 32 mm matched paired head diameters ( p = 0.59). There was also no difference in MLD between titanium or cobalt-chromium stems ( p = 0.79), and regular or high-offset stems ( p = 0.95).Conclusion:There is no statistical difference in femoral head MLD at the head-neck junction in THA between 28-mm and 32-mm matched paired femoral heads, similar or mixed alloy coupled femoral head stem constructs, and regular or high offset stems.


2017 ◽  
Vol 42 (6) ◽  
pp. 2391-2403 ◽  
Author(s):  
Yi-Xuan Chen ◽  
Dao-Yu Zhu ◽  
Zheng-Liang Xu ◽  
Jun-Hui Yin ◽  
Xiao-Wei Yu ◽  
...  

Background: Alcohol abuse is known to be a leading risk factor for atraumatic osteonecrosis of the femoral head (ONFH), in which the suppression of osteogenesis plays a critical role. Cordycepin benefits bone metabolism; however, there has been no study to determine its effect on osteonecrosis. Methods: Human bone mesenchymal stem cells (hBMSCs) were identified by multi-lineage differentiation. Alkaline phosphatase (ALP) activity, RT-PCR, western blots, immunofluorescent assay and Alizarin red staining of BMSCs were evaluated. A rat model of alcohol-induced ONFH was established to investigate the protective role of cordycepin against ethanol. Hematoxylin & eosin (H&E) staining and micro-computerized tomography (micro-CT) were performed to observe ONFH. Apoptosis was assessed by TdT-mediated dUTP nick end labeling (TUNEL). Immunohistochemical staining was carried out to detect OCN and COL1. Results: Ethanol significantly suppressed ALP activity, decreased gene expression of OCN and BMP2, lowered levels of RUNX2 protein, and reduced immunofluorescence staining of OCN and COL1 and calcium formation of hBMSCs. However, these inhibitory effects were attenuated by cordycepin co-treatment at concentrations of 1 and 10 µg/mL Moreover, it was revealed that the osteo-protective effect of cordycepin was associated with modulation of the Wnt/β-catenin pathway. In vivo, by micro-CT, TUNEL and immunohistochemical staining of OCN and COL1, we found that cordycepin administration prevented alcohol-induced ONFH. Conclusion: Cordycepin treatment to enhance osteogenesis may be considered a potential therapeutic approach to prevent the development of alcohol-induced ONFH.


2020 ◽  
Author(s):  
Zhiguo Yuan ◽  
Wei Zhang ◽  
Xiangchao Meng ◽  
Jue Zhang ◽  
Teng TengLong ◽  
...  

Abstract Objective: This study aimed to quantitatively investigate the peri-implant histology of applying defect-size polyether ether ketone (PEEK) implant for the treatment of localized osteochondral defects in the femoral head and compared it with cobalt chromium molybdenum (CoCrMo) alloy implant.Methods: A femoral head osteochondral defect model was created in the left hips of goats (n=12). Defects were randomly treated by immediate placement of a PEEK (n=6) or CoCrMo implant (n=6). The un-operated right hip joints served as a control. Goats were sacrificed at 12 weeks. Periprosthetic cartilage quality was semi-quantitatively analyzed macroscopically and microscopically. Implant osseointegration was measured by micro-CT and histomorphometry.Results: The modified macroscopic articular evaluation score in the PEEK group was lower than that in the CoCrMo group (p<0.05), and the histological score of the periprosthetic and acetabular cartilage in the PEEK group was lower than that in the CoCrMo group (P<0.05). The mean bone-implant contact for PEEK implants was comparable with that for CoCrMo alloy implants at 12 weeks.Conclusions: A PEEK implant for the treatment of local osteochondral defect in the femoral head demonstrated effective fixation and superior in vivo cartilage protection compared with an identical CoCrMo alloy implant.


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