Relação dos Parâmetros Derivados da Bioimpedância Elétrica com o Estado Nutricional de Pacientes em Hemodiálise

Os parâmetros não tradicionais derivados da bioimpedância elétrica (BIA) como reatância, ângulo de fase e massa celular estão cada vez sendo mais utilizados na prática clínica para auxiliar no diagnóstico nutricional dos pacientes com doença renal crônica e, consequentemente, no prognóstico clínico dessa população. O presente estudo teve por objetivo avaliar a relação dos parâmetros derivados da BIA com o estado nutricional de pacientes em hemodiálise. Estudo transversal, realizado com trinta pacientes adultos de uma clínica de Nefrologia localizada na região metropolitana de São Paulo. Foi utilizada a BIA para avaliar esses parâmetros, assim como para avaliar a composição corporal. A amostra foi constituída por homens e mulheres com média de idade de aproximadamente 56 anos. O ângulo de fase dos pacientes foi de 5,9±1,6 graus e apresentou uma correlação negativa com idade (r= -0,69, p< 0,001) e água corporal extracelular (r= -0,93 p< 0,001). A média de reatância foi de 50,9±16,08 ohms e apresentou correlação negativa com a água extracelular (r= -0,82, p<0,001) e positiva com a massa celular (r=0,51, p<0,004). Em relação ao percentual de massa celular, a média foi de 36,8± 6,1%, sendo que a mesma apresentou uma correlação negativa com a idade (r= -0,66, p< 0,001), gordura corporal (r= -0,73, p< 0,001), água corporal extracelular (r= -0,82, p<0,001).Conclui-se que os parâmetros não tradicionais derivados da BIA apresentaram boa associação com o estado nutricional dos pacientes, podendo dessa forma, serem aliados importantes para obtenção do melhor diagnóstico nutricional e, consequentemente, do prognóstico dos mesmos durante o tratamento dialítico.Palavras-chave: Bioimpedância Elétrica. Estado Nutricional. Diálise.AbstractNon-traditional parameters derived from bioelectrical impedance analysis (BIA) as reactance, phase angle and cell mass are increasingly being used in clinical practice to improve the nutritionalstatus of chronic kidney disease patients andthe clinical outcomes in this population. The present study aimed to evaluate the relationship of parameters derived from the BIA with nutritional status of hemodialysis patients. It was a cross-sectional study with 30 adultspatients of a nephrology clinic in the metropolitan region of São Paulo. BIA was used to evaluate as well as to assess the body composition. The mean age of the patients was approximately 56 years. The phase angle of the patients was 5.9 ± 1.6 degrees and it was negatively correlated with age (r = -0.69, p <0.001) andwith extracellular body water (r = -0.93 p <0.001). The mean reactance was 50.9 ± 16.08 ohms and it showed a negative correlation with the extracellular water (r = -0.82, p <0.001) and positively with the body cell mass (r = 0.51, p <0.004). Regarding to the percentage of body cell mass, the mean was 36.8 ± 6.1%, and it presented a negative correlation with age (r = -0.66, p <0.001), body fat (r = -0.73, p <0.001) and with body water extracellular (r = -0.82, p <0.001). The present study concluded that non-traditional parameters derived from BIA showed a good association with the nutritional status of hemodialysis patients. It is important for getting the best nutritional diagnosis and consequently the prognosis of these patientsduring the dialysis treatment.Keywords: Bioelectrical Impedance. Nutritional Status. Dialysis.

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Phase Angle and Body Cell Mass for Assessment of Nutritional Status and Clinical Outcome in Chronic Hemodialysis Patients

Journal of Renal Nutrition ◽

10.1053/j.jrn.2017.01.012 ◽

2017 ◽

Vol 27 (2) ◽

pp. 144

Keyword(s):

Clinical Outcome ◽

Nutritional Status ◽

Phase Angle ◽

Cell Mass ◽

Hemodialysis Patients ◽

Chronic Hemodialysis ◽

Body Cell Mass ◽

Body Cell

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PP148-SUN ARE BODY CELL MASS AND PHASE ANGLE (PA) MEASURED BY BIOELECTRICAL IMPEDANCE (BIA), RELATED WITH FOOD INTAKE IN CARCINOMA PATIENTS?

Clinical Nutrition Supplements ◽

10.1016/s1744-1161(12)70200-4 ◽

2012 ◽

Vol 7 (1) ◽

pp. 85

Author(s):

A. Andreoli ◽

A.M. Morelli ◽

S. Mariotti ◽

I. Liotti ◽

S. Simeoni ◽

...

Keyword(s):

Food Intake ◽

Phase Angle ◽

Cell Mass ◽

Bioelectrical Impedance ◽

Body Cell Mass ◽

Body Cell

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Phase Angle and Bioelectrical Impedance Vectors in Adolescent and Adult Male Athletes

International Journal of Sports Physiology and Performance ◽

10.1123/ijspp.2013-0397 ◽

2014 ◽

Vol 9 (5) ◽

pp. 798-804 ◽

Cited By ~ 28

Author(s):

Josely C. Koury ◽

Nádia M.F. Trugo ◽

Alexandre G. Torres

Keyword(s):

Phase Angle ◽

Water Retention ◽

Cell Mass ◽

Bioelectrical Impedance ◽

Single Frequency ◽

Body Cell Mass ◽

Adolescent Athletes ◽

Basketball Players ◽

Male Athletes ◽

Body Cell

The aim of the current study was to assess phase angle (PA) and bioelectrical impedance vectors (BIVA) in adolescent (n = 105, 12–19 y) and adult (n = 90, 20–50 y) male athletes practicing varied sports modalities. Bioelectrical impedance analysis (BIA) was performed with a single-frequency tetrapolar impedance analyzer after the athletes had fasted overnight for 8 h. PA and BIVA were determined from BIA data. PA presented correlations (P < .01) with body-mass index (r = .58) in all athletes and also with age in adolescent (r = .63) and adult (r = –.27) athletes. Compared with adults, adolescent athletes presented lower PA and higher frequency of PA below the 5th percentile of a reference population (P < .001). The adolescents with low PA were mostly football and basketball players. The BIVA confidence ellipses of adult and adolescent athletes were different (P < .001) between them and from their respective reference populations and were closer than those of adult and adolescent nonathletes. About 80% of the athletes were in the 95th percentile of BIVA tolerance ellipses and in quadrants consistent with adequate body cell mass and total body water. The adolescent athletes outside the 95th percentile ellipse were all football and basketball players who showed indications of decreased water retention and body cell mass and of increased water retention, respectively. PA and BIVA ellipses showed that the intense training routine of the athletes changed functional and hydration parameters and that the magnitude of these changes in adolescents may depend on the sport modality practiced.

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Bioelectrical Impedance Vector Analysis and Phase Angle on Different Oral Zinc Supplementation in Eutrophic Children: Randomized Triple-Blind Study

Nutrients ◽

10.3390/nu11061215 ◽

2019 ◽

Vol 11 (6) ◽

pp. 1215 ◽

Cited By ~ 1

Author(s):

Karina M. Vermeulen ◽

Márcia Marília G. D. Lopes ◽

Camila X. Alves ◽

Naira J. N. Brito ◽

Maria das Graças Almeida ◽

...

Keyword(s):

Cell Membrane ◽

Phase Angle ◽

Cell Mass ◽

Serum Zinc ◽

Bioelectrical Impedance ◽

Vector Analysis ◽

Body Cell Mass ◽

Body Cell ◽

Bioelectrical Impedance Vector Analysis ◽

Impedance Vector

The parameters derived from bioelectrical impedance, phase angle (PA) and bioelectrical impedance vector analysis (BIVA) have been associated with cell membrane integrity and body cell mass. Zinc is a micronutrient that exerts important structural functions and acts in maintaining cellular functionality. To evaluate cell integrity and body cell mass, PA and BIVA were evaluated in children orally supplemented with zinc at different concentrations. Anthropometric, bioelectrical (resistance and reactance) and serum zinc variables were collected from two randomized, triple-blind, controlled clinical trials. Sampling was composed of 71 children consisting of three groups: a control group who received a placebo and two experimental groups who received oral supplementation of 5 or 10 mg-Zn/day for three months. The three groups presented increases (p < 0.001) in the linear height and weight. In the group supplemented with 10 mg-Zn/day, there was an increase in reactance values (p = 0.036) and PA (p = 0.002), in addition to vector displacement (p < 0.001) in relation to the confidence ellipses. An increase in serum zinc concentration was found (p < 0.001) in all three groups. Whit this, the supplementation with 10 mg-Zn/day promotes changes in the integrity of the cell membrane associated with the increase in the cellular mass of healthy children.

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Bioelectrical Impedance in Clinical Practice

DICP ◽

10.1177/1060028089023007-803 ◽

1989 ◽

Vol 23 (7-8) ◽

pp. 548-555 ◽

Cited By ~ 27

Author(s):

Barbara J. Zarowitz ◽

Alison M. Pilla

Keyword(s):

Body Composition ◽

Clinical Practice ◽

Low Voltage ◽

Cell Mass ◽

Bioelectrical Impedance ◽

The Body ◽

Pharmacokinetic Parameters ◽

Composition Analysis ◽

Body Cell Mass ◽

Body Cell

Bioelectrical impedance (BI) relies on the conduction of a low-voltage alternating current through the body. Lean tissue and fluids containing electrolytes conduct the current and cell membranes serve as capacitors and account for capacitive resistance. Fat and bone are poor conductors. Measurement of the voltage drop of the applied current yields resistance (R) and reactance (Xc). R and Xc are used with height, weight, age, and gender in a number of multiple regression relationships to predict body composition compartments such as fat-free mass, lean body mass, extracellular mass, and body cell mass. The technique has been compared with and validated against traditional measures of body composition analysis. In clinical practice, BI has been used to monitor fluid status in burn and dialysis patients, assess changes of body cell mass with nutritional repletion, and predict pharmacokinetic parameters and dose of theophylline and aminoglycoside antibiotics. BI is a noninvasive, safe, rapid, and reproducible technique with exciting potential in clinical practice.

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