scholarly journals Role of carbon dioxide laser in the treatment of oral leukoplakia

2020 ◽  
Vol 7 (10) ◽  
pp. 3411
Author(s):  
Pankaj Kshirsagar ◽  
Prabhat B. Nichkaode ◽  
Dipti A. Patil ◽  
Balajiprathep Santhan

The aim of the present study is to evaluate the treatment results of carbon dioxide (CO2) laser vaporisation in the well-defined cohort patients with oral leukoplakia. The group consisted of 20 patients. Before treatment, a clinical photograph and an incisional biopsy were performed in all the cases. Also, post treatment results were documented with clinical photographs. The mean follow-up period was 12 months. 18 out of 20 patients treated for cure (90%) achieved local control after one treatment. The remaining 2 patients required (10%) 2nd and 3rd vaporisations. The rate of malignant transformation after CO2 laser treatment is found to be 2.27% which is comparable to the other studies. CO2 laser vaporisation in the treatment of oral leukoplakia lesions is an excellent procedure in not only preventing the local recurrence and the malignant transformation but also in preventing the post-operative dysfunction. It is a time saving procedure with a negligible intra operative bleeding. The wound healing procedure after CO2 laser is extremely good causing the least post procedure morbidity.

2016 ◽  
Vol 8 (2) ◽  
pp. 142-150 ◽  
Author(s):  
Imane Bennani ◽  
Raphael Lopez ◽  
Delphine Bonnet ◽  
Gregoire Prevot ◽  
Arnaud Constantin ◽  
...  

Limited mouth opening (LMO) is a frequent complication of systemic sclerosis (SS). Its management is complex and there are limited treatment options. We report four patients with SS and severe LMO [interincisal distance (IID) <30 mm] treated with pulsed carbon dioxide (CO2) laser. Pulsed CO2 laser treatment of the white lips was performed after all patients had signed a written informed consent in the absence of alternative treatment. Treatment was carried out under locoregional anaesthesia using a Sharplan 30C CO2 laser in the Silk Touch® resurfacing mode. One to three laser sessions were performed at intervals of 8-12 months between sessions. Assessments were performed at 3 and 12 months with measurement of the IID using a ruler, calculation of the Mouth Handicap in Systemic Sclerosis (MHISS) scale and global evaluation by the patients. Adverse events were also reported. In all four patients, an improvement in IID occurred 3 months after the first session with a mean gain of +5 mm (range: 2-7). At 12 months, a mean gain of +8.5 mm (range: 7-10) in IID was observed. The MHISS score decreased by a mean of -14 (range: 11-17). All patients showed improvement of lip flexibility or mouth opening, allowing better phonation and mastication and easier dental care. Adverse effects were transient erythema and/or dyschromia. CO2 laser appears to be effective and well tolerated in the improvement of LMO in SS.


2014 ◽  
Vol 25 (1) ◽  
pp. 8-13
Author(s):  
Yui ENOMOTO ◽  
Hiroaki SUZUKI ◽  
Tomoko ASAI ◽  
Manabu SHIGEOKA ◽  
Kousuke MATSUMOTO ◽  
...  

Author(s):  

Background: Many interventions have been used to treat post-acne scars, with various degrees of efficacy and adverse reactions. Multimodal approach can achieve better results for improving the physical appearance that even if minor may result in significant distress and reduced quality of life. Objective: To compare the efficacy of subcision with fractional carbon dioxide (CO2) laser and subcision with microneedling fractional radiofrequency (RF) in treating post-acne scars and to study their adverse effects. Methods: In this prospective, interventional clinical study, a total of 64 patients with post-acne scars were enrolled. The patients were randomly allocated into two groups of 32 patients each, in which group A was treated with subcision plus fractional carbon dioxide laser (CO2) and group B was treated with subcision plus microneedling fractional radiofrequency (RF) every 6 weeks for a total of four sittings. An objective score was calculated for each patient using the Goodman and Baron scale to evaluate the outcome every visit during treatment and then 3 months after completion of therapy. Results: In group A, the percentage reduction in the mean objective scores was found to be 64%. In group B, the percentage reduction in mean objective scores was found to be 42%. Most of the changes were seen in the boxcar and rolling types of scars. Conclusions: Subcision and fractional CO2 laser were considered superior over subcision with microneedling fractional (RF) technique for the treatment of post-acne scars. Boxcar and rolling types of scars showed a high response to treatment than icepick scars


2010 ◽  
Vol 46 (6) ◽  
pp. 375-384 ◽  
Author(s):  
Sara M. Burns ◽  
Elizabeth W. Howerth ◽  
Clarence A. Rawlings ◽  
Karen K. Cornell ◽  
MaryAnn G. Radlinsky ◽  
...  

This study compared the collateral tissue damage and incisional bridging with granulation tissue via histopathological examination following feline onychectomy performed by radiofrequency (RF) and carbon dioxide (CO2) laser. Two cats were euthanized, and their digits were harvested for histopathological evaluation on days 1, 3, and 7 post-onychectomy. Each digit was evaluated for total lesion width, total necrosis width, and degree of edema, hemorrhage, and inflammation. This study found few significant differences in collateral tissue damage between RF and CO2 laser, but more incisional bridging by granulation tissue was noted with RF for feline onychectomies. These results indicate that RF for feline onychectomy is a reasonable alternative to CO2 laser in regard to collateral tissue damage and bridging of the incision by granulation tissue. In addition, RF is not accompanied by the strict safety considerations and initial expense of acquisition of a CO2 laser.


2014 ◽  
Vol 08 (01) ◽  
pp. 118-123 ◽  
Author(s):  
Ajit George Mohan ◽  
A. V. Rajesh Ebenezar ◽  
Mohamed Fayas Ghani ◽  
Leena Martina ◽  
Ashwin Narayanan ◽  
...  

ABSTRACT Aim: The aim of this study was to evaluate the surface/mineral changes on enamel before and after the application of acidulated phosphate fluoride (APF) gel, fluoride enhanced hydroxyapatite gel and propolis in conjunction with carbon-dioxide (CO2) laser. Materials and Methods: Crowns of 40 human maxillary central incisors were collected and were divided into four groups of 10 each: Topical fluoride application only, topical fluoride application followed by CO2 laser irradiation, CO2 laser irradiation followed by topical fluoride application and CO2 laser irradiation before and after topical fluoride application. The 10 crowns in each group was again sectioned into four equal parts of mesio-incisal, disto-incisal, mesio-cervical and disto-cervical sections rendering 40 samples in each group. Each group was again subdivided into four subgroups: Subgroup C - untreated enamel surface (control). Subgroup A - APF gel application, subgroup R - fluoride enhanced hydroxyapatite gel application and subgroup P - propolis application. The surface morphology of the test samples were analyzed by scanning electron microscopy and mineral changes by energy dispersion X-ray spectrophotometer. Results: Total mineral content is maximum in Group 4A (CO2 laser irradiation before and after APF gel application) and calcium/phosphate ratio is highest in Group 4R (CO2 laser irradiation before and after Remin-Pro application). Group 2A (APF gel application followed by CO2 laser irradiation) has the maximum fluoride retention. Conclusion: Laser irradiation of enamel through a topically applied APF gel is effective in the prophylaxis and management of dental caries.


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