scholarly journals A prospective comparative study on the use of nanocrystalline silver ion dressing with normal saline dressing in diabetic foot ulcers

2021 ◽  
Vol 8 (5) ◽  
pp. 1554
Author(s):  
Vamsi K. Malligurki ◽  
Samar Fatima ◽  
Ruhee Anmol ◽  
Prashanth Annayyanapalya Thimmegowda
Keyword(s):  
Normal Saline ◽  
Diabetic Foot ◽  
Silver Ion ◽  
Wound Dressings ◽  
Foot Ulcers ◽  
Control Group ◽  
Study Group ◽  
Diabetic Foot Ulcers ◽  
Prospective Comparative Study ◽  
Wound Discharge

Background: A diabetic foot is any pathology that results directly from peripheral arterial disease and/or sensory neuropathy affecting the feet in diabetes mellitus. Proper assessment of the wound followed by an aggressive multidisciplinary approach can reduce the risk of amputation, thereby greatly increasing the patient’s quality of life. Wound dressings play a vital role in diabetic foot care management. Nanocrystalline silver ion dressing is a newer modality that has been in consideration for the treatment of diabetic wounds.Methods: This was a prospective comparative study conducted in the department of general surgery, Sagar hospital-DSI, Bangalore from December 2020 to March 2021. A total of 50 diabetic patients were included in the study and were randomised into the study group and control group. The study group received nanocrystalline silver ion dressings while the control group received dressings with normal saline. Patients were observed for 8 weeks. Data regarding the presence of wound discharge, type of discharge, granulation tissue, presence of slough and changes in the size of the wound was recorded and analysed.Results: Study group showed statistically significant better outcomes (p<0.05) in terms of reduced wound discharge, early granulation tissue, rapid reduction of slough from wounds and reduction in the wound size when compared with the control group. 17 patients responded completely in the study group when compared with the control group, where 8 patients have got a complete response (p<0.05).Conclusions: Wound dressings with nanocrystalline silver ion helps in the early healing of diabetic foot ulcers when compared to normal saline dressings.

scholarly journals Efficacy of low level infrared light therapy on wound healing in patients with chronic diabetic foot ulcers: a randomised control trial

2019 ◽  
Vol 6 (5) ◽  
pp. 1650
Author(s):  
Mimamaychet B. Sangma ◽  
Selvakumaran Selvaraju ◽  
Fremingston Marak ◽  
Simon David Dasiah
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Foot ◽  
Financial Burden ◽  
Infrared Light ◽  
Randomised Control Trial ◽  
Foot Ulcers ◽  
Control Group ◽  
Study Group ◽  
Diabetic Foot Ulcers ◽  
Significant Difference

Background: A total of 52-patients with Type-2 Diabetes Mellitus having Meggitt-Wagner Grade-I of foot ulcers of at least more than 4-weeks duration, less than 6×6 cm, with negative culture were studied. Diabetic foot ulcers are serious complications of diabetes mellitus and are known to be resistant to conventional treatment. It also causes a significant cause of morbidity, mortality and financial burden. If the ulcer is left untreated they can create a severe complications. This study was designed to examine the effect of infrared radiation on the healing of diabetic foot ulcer.Methods: This clinical trial was performed on 52 patients with diabetic foot ulcer Wagner Grade-I. Patients were classified into 26 control and 26 study group. Electromagnetic radiations in the form of photons are delivered to the ulcer site by infrared light to stimulate healing.Results: Male preponderance was found with ratio of 2:1. Mean age of the patients was 58.82 years in control group and 52.44 years in study group. The mean HbA1C levels in the control groups were 7 (range 6.2-8.3%) and 7.2 (range 7-8%) in the study group, suggesting no biochemical differences between two groups. Mean reduction in the ulcer area was 375.30 mm in the control group and 893.56 mm in the study group and this differences between the two groups was statistically significant (p<0.010).Conclusions: It is shown that using infrared plus routine dressing is more effective than merely routine dressing in diabetic foot ulcers and there was a significant difference in reduction of ulcer size in study group.

Innovation and new technologies in hydrogel wound dressings for treating diabetic foot ulcers: a twenty-year review

Cytotherapy ◽  
2021 ◽  
Vol 23 (5) ◽  
pp. S184
Author(s):  
J.E. Ävila-Quiroga ◽  
V. Pinzön-Mora ◽  
V.A. Solarte-David ◽  
S.M. Becerra-Bayona ◽  
M.L. Luna-Gonzalez
Keyword(s):  
Diabetic Foot ◽  
New Technologies ◽  
Wound Dressings ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers

Evaluation of the role of hyperbaric oxygen therapy in the treatment of diabetic foot ulcers: a prospective comparative study

2016 ◽  
Vol 88 (4) ◽  
pp. 219-224 ◽  
Author(s):  
Chandrakant Munjewar ◽  
Ishaq Nabi ◽  
Santosh Gautam ◽  
Neelam Ahirwar ◽  
Poras Chaudhary ◽  
...  
Keyword(s):  
Comparative Study ◽  
Hyperbaric Oxygen ◽  
Diabetic Foot ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Prospective Comparative Study

scholarly journals Combination of Shengji ointment and bromelain in the treatment of exposed tendons in diabetic foot ulcers: Study protocol for a non-blind, randomized, positive control clinical trial

2021 ◽  
Author(s):  
yang zhao ◽  
rui gao ◽  
Xinyue Dai ◽  
Xu Sun ◽  
Zhaohui Zhang ◽  
...  
Keyword(s):  
Granulation Tissue ◽  
Diabetic Foot ◽  
Combined Treatment ◽  
Positive Control ◽  
Foot Ulcers ◽  
Control Group ◽  
Diabetic Foot Ulcers ◽  
Loss Of Function ◽  
Tendon Tissue ◽  
Factors Affecting

Abstract Background : Diabetic foot ulcers often affect tendon tissue. Consequently, the infection may spread proximally along the tendon, leading to amputation or even the death of patients. Exposed, degenerated, and necrotic tendons are key factors affecting the healing of diabetic foot ulcers. The effective treatment of the tendon involvement may positively affect the prognosis. In clinical practice, treatment with Shengji ointment and bromelain induces islands of granulation tissue on the denatured tendon surface, which gradually grows and merges. Ideally, the exposed tendon is covered entirely by granulation tissue. This trial aims to assess the effect of a combined treatment regime of Shengji ointment, which has been shown to regenerate muscle tissue and pineapple protease in preventing the loss of function and amputation caused by tendon necrosis. This trial will provide high-quality evidence for the effectiveness of this combination in healing diabetic ulcers with tendon necrosis. Methods: The sample size will be 180 patients who will be randomly assigned 1:1 to a treatment group (90 patients) using Shengji ointment combined with bromelain and a control group (90 patients) using hydrocolloid dressing. Both groups will continue their conventional treatments, such as blood glucose and blood pressure medication, lipid regulation, antiplatelets, and others. The primary outcome will be the wound coverage with granulation tissue. Secondary outcomes will be the wound healing rate, amputation extent (where needed), time to granulation, and the Maryland Foot Score. Other efficacy outcomes will be the time to debridement of necrotic tendon tissue and granulation tissue score. Discussion: This study will treat patients with diabetic foot ulcers with exposed, degenerated, and necrotic tendons with Shengji ointment and bromelain. The trial aims to promote regeneration and healing, to preserve the limb and its function, and to develop a comprehensive and effective protocol that can be applied to promote the healing of exposed tendons in diabetic foot wounds. Trial registration: ChiCTR2000039327; date of registration: 2020-10-23. http://www.chictr.org.cn/com/25/showproj.aspx?proj=62692

scholarly journals Effect of Health Education on Improving the Knowledge among Diabetes Mellitus Patients in the Prevention of Diabetic Ulcer in Regional Hospital of Tidore Island

2021 ◽  
Vol 4 (4) ◽  
pp. 379-384
Author(s):  
Haeril Amir ◽  
Nur Wahyuni Munir
Keyword(s):  
Diabetes Mellitus ◽  
Health Education ◽  
Diabetic Foot ◽  
Regional Hospital ◽  
Foot Ulcers ◽  
Control Group ◽  
Diabetic Patients ◽  
Diabetic Foot Ulcers ◽  
Diabetic Ulcer ◽  
Diabetic Ulcers

International  Diabetes  Federation  (IDF) reported that the number of diabetes mellitus patients worldwide increases every year. Diabetes mellitus is a chronic disease due to damage to the pancreas in producing enough insulin and characterized by impaired metabolism of fats, increased blood sugar, carbohydrates and protein both absolutely and relatively. Diabetic foot ulcers (DFU) are among the most common complications in diabetic patients and are associated with high mortality, morbidity, and health costs.   This study was to determine the effect of health education on knowledge improvement about diabetic ulcers in the regional hospital of Tidore Islands.  This research is a quasi-experimental type with a pretest-posttest without a control group design. The research sample consisted of 30 respondents who met the inclusion criteria. Data were analyzed using a paired test and processed with statistic version 21. Based on the research results, there was an improved knowledge in pre and post-health education counseling, where the average score before health education counseling was 11.6. After health counseling, the average value was 15.0. The results showed the effect of knowledge in the prevention of diabetic ulcers with a p-value =0,000.  Health education is an effort to improve patient's ability to prevent diabetic foot ulcers that have been proven in several scientific studies. Health education methods provide additional information so that patients who previously wondered about their disease can directly ask health workers. Health education affects the knowledge improvement of Diabetes Mellitus patients in the Regional hospital of Tidore Islands  

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