scholarly journals Efficacy of low level infrared light therapy on wound healing in patients with chronic diabetic foot ulcers: a randomised control trial

2019 ◽  
Vol 6 (5) ◽  
pp. 1650
Author(s):  
Mimamaychet B. Sangma ◽  
Selvakumaran Selvaraju ◽  
Fremingston Marak ◽  
Simon David Dasiah
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Foot ◽  
Financial Burden ◽  
Infrared Light ◽  
Randomised Control Trial ◽  
Foot Ulcers ◽  
Control Group ◽  
Study Group ◽  
Diabetic Foot Ulcers ◽  
Significant Difference

Background: A total of 52-patients with Type-2 Diabetes Mellitus having Meggitt-Wagner Grade-I of foot ulcers of at least more than 4-weeks duration, less than 6×6 cm, with negative culture were studied. Diabetic foot ulcers are serious complications of diabetes mellitus and are known to be resistant to conventional treatment. It also causes a significant cause of morbidity, mortality and financial burden. If the ulcer is left untreated they can create a severe complications. This study was designed to examine the effect of infrared radiation on the healing of diabetic foot ulcer.Methods: This clinical trial was performed on 52 patients with diabetic foot ulcer Wagner Grade-I. Patients were classified into 26 control and 26 study group. Electromagnetic radiations in the form of photons are delivered to the ulcer site by infrared light to stimulate healing.Results: Male preponderance was found with ratio of 2:1. Mean age of the patients was 58.82 years in control group and 52.44 years in study group. The mean HbA1C levels in the control groups were 7 (range 6.2-8.3%) and 7.2 (range 7-8%) in the study group, suggesting no biochemical differences between two groups. Mean reduction in the ulcer area was 375.30 mm in the control group and 893.56 mm in the study group and this differences between the two groups was statistically significant (p<0.010).Conclusions: It is shown that using infrared plus routine dressing is more effective than merely routine dressing in diabetic foot ulcers and there was a significant difference in reduction of ulcer size in study group.

scholarly journals Effect of Health Education on Improving the Knowledge among Diabetes Mellitus Patients in the Prevention of Diabetic Ulcer in Regional Hospital of Tidore Island

2021 ◽  
Vol 4 (4) ◽  
pp. 379-384
Author(s):  
Haeril Amir ◽  
Nur Wahyuni Munir
Keyword(s):  
Diabetes Mellitus ◽  
Health Education ◽  
Diabetic Foot ◽  
Regional Hospital ◽  
Foot Ulcers ◽  
Control Group ◽  
Diabetic Patients ◽  
Diabetic Foot Ulcers ◽  
Diabetic Ulcer ◽  
Diabetic Ulcers

International  Diabetes  Federation  (IDF) reported that the number of diabetes mellitus patients worldwide increases every year. Diabetes mellitus is a chronic disease due to damage to the pancreas in producing enough insulin and characterized by impaired metabolism of fats, increased blood sugar, carbohydrates and protein both absolutely and relatively. Diabetic foot ulcers (DFU) are among the most common complications in diabetic patients and are associated with high mortality, morbidity, and health costs.   This study was to determine the effect of health education on knowledge improvement about diabetic ulcers in the regional hospital of Tidore Islands.  This research is a quasi-experimental type with a pretest-posttest without a control group design. The research sample consisted of 30 respondents who met the inclusion criteria. Data were analyzed using a paired test and processed with statistic version 21. Based on the research results, there was an improved knowledge in pre and post-health education counseling, where the average score before health education counseling was 11.6. After health counseling, the average value was 15.0. The results showed the effect of knowledge in the prevention of diabetic ulcers with a p-value =0,000.  Health education is an effort to improve patient's ability to prevent diabetic foot ulcers that have been proven in several scientific studies. Health education methods provide additional information so that patients who previously wondered about their disease can directly ask health workers. Health education affects the knowledge improvement of Diabetes Mellitus patients in the Regional hospital of Tidore Islands  

scholarly journals Assessment role of phagocytic neutrophil cells among different Wagner’s grades of diabetic foot ulcers infections

2020 ◽  
Author(s):  
Eidha Ali Bin-Hameed ◽  
Maryam Hamed Baras
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Foot ◽  
Foot Ulcers ◽  
Control Group ◽  
Diabetic Patients ◽  
Gram Negative Bacteria ◽  
Diabetic Foot Ulcers ◽  
Bacterial Isolates ◽  
Gram Negative

Abstract Background: Foot ulcers complications in diabetes mellitus (DM) patients are one of the significant medical problems and an economic burden. The aim of this study is to assessment role of phagocytic neutrophil cells and its relationship with the incidence of diabetic foot ulcers (DFU) infection of diabetic patients. A total of 60 venipuncture blood samples collected from diabetes mellitus, diabetic foot ulcer patients and healthy persons as control group. 20 swabs from the DFU patients were collected and processed for culture and susceptibility test after the ulcers classified according to Wagner’s grades system. Phagocytic cells activity test was performed to determine the efficiency of phagocytic neutrophil cells in diabetic patients. Results: Gram positive bacteria were the most prevalent in the DFU patients 57.1% with statistical significant relationship between the type of bacteria and grades of Wagner’s classification followed by Gram negative bacteria in high grades of ulcers. Wagner’s ulcers grade 1 and 2 were the most prevalence in DFU patients 30%. There was a weak negative correlation between the efficiency of phagocytic neutrophil cells activity and grade ulcers classified (r = -0.323). Amikacin and ciprofloxacin were the most effective antibiotics against 90.5% and 81% of the bacterial isolates respectively, whereas ampicillin, cefepime and cefadroxil were less effective antibiotics against the bacterial isolates.Conclusion: When the grade of ulcer increased, the bacterial resistance to antibiotics increased, and this was emphasis the correlation with prevalent of Gram negative bacteria in the high grade of ulcers with high resistance of antibiotics. In contrast, the grade of ulcer increased, the efficiency of phagocytic neutrophil cells decreased.

scholarly journals Financial burden of diabetic foot ulcers to world: a progressive topic to discuss always

2017 ◽  
Vol 9 (1) ◽  
pp. 29-31 ◽  
Author(s):  
Alok Raghav ◽  
Zeeshan Ahmad Khan ◽  
Rajendra Kumar Labala ◽  
Jamal Ahmad ◽  
Saba Noor ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Developing Countries ◽  
Diabetic Foot ◽  
Social Impact ◽  
Financial Burden ◽  
Developed Countries ◽  
Foot Ulcers ◽  
Diabetic Patients ◽  
Diabetic Foot Ulcers ◽  
Foot Complications

Diabetic foot complications are the most common occurring problems throughout the globe, resulting in devastating economic crises for the patients, families and society. Diabetic foot ulcers (DFUs) have a neuropathic origin with a progressive prevalence rate in developing countries compared with developed countries among diabetes mellitus patients. Diabetic patients that are of greatest risk of ulcers may easily be diagnosed with foot examination. Economic burden may be carefully examined. The budget costing must include both the clinical and social impact of the patients.

Severe Vitamin D3 Deficiency in the Majority of Patients with Diabetic Foot Ulcers

2018 ◽  
Vol 50 (08) ◽  
pp. 615-619 ◽  
Author(s):  
Joachim Feldkamp ◽  
Karsten Jungheim ◽  
Matthias Schott ◽  
Beatrix Jacobs ◽  
Michael Roden
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Foot ◽  
Cell Function ◽  
Glycosylated Hemoglobin ◽  
Diabetic Foot Syndrome ◽  
Foot Ulcers ◽  
Control Group ◽  
Diabetic Foot Ulcers ◽  
Healthy Humans ◽  
Patients With Diabetes

AbstractDiabetic foot ulcers are a severe complication in patients with diabetes mellitus. Vitamin D is associated with impaired β-cell function and insulin resistance, and is necessary for wound healing and bone metabolism. We measured the serum concentrations of 25-hydroxyvitamin D3 in 104 patients (63 inpatients, 41 outpatients) with diabetic foot ulcers and compared them to 99 healthy humans (control) and 103 patients with diabetes mellitus type 2 without diabetic foot ulcers. Calcium, creatinine, and parathyroid hormone were measured in patients with diabetic foot ulcers. The data were analysed together with glycosylated hemoglobin A1c and the severity of diabetic foot lesions according to the Armstrong classification. Levels of 25-hydroxyvitamin D3 were lower (11.8±11.3 ng/ml, p<0.001) in patients with diabetic foot ulcers (mean age 70±12 years) than in the control group (27.2±12.2 ng/ml). No difference was found between in- and outpatients. Fifty-eight (55.8%) of patients with diabetic foot ulcers had a severe 25-hydroxyvitamin D3 deficiency with levels below 10 ng/ml. Only 12% of the patients had 25-hydroxyvitamin D3 levels above 20 ng/ml. Secondary hyperparathyroidism was found in 27.9% of patients and 11.5% of the patients were hypocalcemic. There was a negative correlation (r=–0.241) (p<00.1) between Armstrong classification and 25-hydroxyvitamin D3 status. In conclusion, patients with diabetic foot syndrome are at high risk of 25-hydroxyvitamin D3 deficiency. Thus, any patient with diabetic foot syndrome should undergo 25-hydroxyvitamin D3 measurement and supplementation, if values are found to be decreased.

scholarly journals Effects of a Short Educational Program for the Prevention of Foot Ulcers in High-Risk Patients: A Randomized Controlled Trial

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Matteo Monami ◽  
Stefania Zannoni ◽  
Marianna Gaias ◽  
Besmir Nreu ◽  
Niccolò Marchionni ◽  
...  
Keyword(s):  
High Risk ◽  
Diabetic Foot ◽  
Educational Program ◽  
Foot Ulcers ◽  
Control Group ◽  
Diabetic Patients ◽  
Diabetic Foot Ulcers ◽  
High Risk Patients ◽  
Significant Difference ◽  
Risk Patients

Background. Patient education is capable of reducing the risk for diabetic foot ulcers. However, specific education on foot ulcer prevention was either included in broader programs addressing different parts of diabetes care or provided with time- and resource-consuming curricula. The aim of the study is to assess the feasibility and efficacy of a brief educational program for the prevention of diabetic foot ulcers in high-risk patients.Methods. The study was performed on type 2 diabetic patients, randomized in a 1 : 1 ratio either to intervention or to control group. The principal endpoint was the incidence of foot ulcers. The intervention was a two-hour program provided to groups of 5–7 patients, including a 30-minute face-to-face lesson on risk factors for foot ulcers, and a 90-minute interactive session with practical exercises on behaviors for reducing risk.Results. The study was prematurely terminated due to a highly significant difference in outcome between the two treatment groups. The final sample was therefore composed of 121 patients. Six patients, all in the control group, developed ulcers during the 6-month follow-up (10% versus 0%,p=0.012).Conclusions. A brief, 2-hour, focused educational program is effective in preventing diabetic foot ulcers in high-risk patients.

scholarly journals A prospective comparative study on the use of nanocrystalline silver ion dressing with normal saline dressing in diabetic foot ulcers

2021 ◽  
Vol 8 (5) ◽  
pp. 1554
Author(s):  
Vamsi K. Malligurki ◽  
Samar Fatima ◽  
Ruhee Anmol ◽  
Prashanth Annayyanapalya Thimmegowda
Keyword(s):  
Normal Saline ◽  
Diabetic Foot ◽  
Silver Ion ◽  
Wound Dressings ◽  
Foot Ulcers ◽  
Control Group ◽  
Study Group ◽  
Diabetic Foot Ulcers ◽  
Prospective Comparative Study ◽  
Wound Discharge

Background: A diabetic foot is any pathology that results directly from peripheral arterial disease and/or sensory neuropathy affecting the feet in diabetes mellitus. Proper assessment of the wound followed by an aggressive multidisciplinary approach can reduce the risk of amputation, thereby greatly increasing the patient’s quality of life. Wound dressings play a vital role in diabetic foot care management. Nanocrystalline silver ion dressing is a newer modality that has been in consideration for the treatment of diabetic wounds.Methods: This was a prospective comparative study conducted in the department of general surgery, Sagar hospital-DSI, Bangalore from December 2020 to March 2021. A total of 50 diabetic patients were included in the study and were randomised into the study group and control group. The study group received nanocrystalline silver ion dressings while the control group received dressings with normal saline. Patients were observed for 8 weeks. Data regarding the presence of wound discharge, type of discharge, granulation tissue, presence of slough and changes in the size of the wound was recorded and analysed.Results: Study group showed statistically significant better outcomes (p<0.05) in terms of reduced wound discharge, early granulation tissue, rapid reduction of slough from wounds and reduction in the wound size when compared with the control group. 17 patients responded completely in the study group when compared with the control group, where 8 patients have got a complete response (p<0.05).Conclusions: Wound dressings with nanocrystalline silver ion helps in the early healing of diabetic foot ulcers when compared to normal saline dressings.

scholarly journals Edukasi Kesehatan: Perawatan Kaki terhadap Pengetahuan, Sikap dan Tindakan Pencegahan Ulkus Kaki Diabetik

2019 ◽  
Vol 8 (1) ◽  
pp. 23
Author(s):  
Munali Munali ◽  
Kusnanto Kusnanto ◽  
Hanik Endang Nihayati ◽  
Hidayat Arifin ◽  
Rifky Octavia Pradipta
Keyword(s):  
Diabetes Mellitus ◽  
Health Education ◽  
Diabetic Foot ◽  
Sampling Technique ◽  
Foot Ulcers ◽  
Rank Test ◽  
Control Group ◽  
Diabetic Foot Ulcers ◽  
Foot Care ◽  
Control Group Design

Introduction: People with diabetes mellitus were at 15% risk of developing diabetic foot ulcers. Diabetic foot ulcers can be prevented if people with DM have the knowledge, positive attitude and thus able to perform the diabetic foot care. The aim was to determine the effect of health education on knowledge, attitudes and preventionof diabetic foot ulcers of people with diabetes mellitus. Method: quasi-experiment research design pretest-posttest control group design. Sample was DM patients who visited the Bangkalan City Health Center, recruited by purposive sampling technique with sample size of 35 people in the treatment group and 35 people in the control group. Independent variable was the health education and the dependent variables were knowledge, attitudes and of diabetic foot ulcers. Data were collected with questionnaires andthen analyzed by Wilcoxon Sign Rank Test and Mann-Whitney Test.Result: The results showed that there was an effect of health education on knowledge (p=0.000), attitudes (p=0.000) and preventive actions (p=0.000) of diabetic foot ulcers.Conclussion: Health education was important as an effort to persuade DM patients to take charge on their knowledge and attitude foot care by firstly enhancing.

scholarly journals Staphylococcus aureus strains isolated from diabetic foot ulcers. Identification of the antibiotic resistant phenotypes

2013 ◽  
Vol 20 (4) ◽  
pp. 389-393 ◽  
Author(s):  
Teodora Chiţă ◽  
Delia Muntean ◽  
Luminiţa Badiţoiu ◽  
Bogdan Timar ◽  
Roxana Moldovan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Staphylococcus Aureus ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Foot Ulcers ◽  
Resistance Pattern ◽  
Diabetic Patients ◽  
Diabetic Foot Ulcers ◽  
Bacterial Strains ◽  
Diabetes Clinic

Abstract Background and aims: Infected foot ulcer is one of the most feared complications of diabetes mellitus. Staphylococcus aureus is the most frequently isolated pathogen in diabetic foot infections. The aim of this study was to evaluate the prevalence of S. aureus strains involved in producing foot infections in diabetic patients and the antibiotic resistance pattern of these strains. Material and methods: The study included 33 S. aureus strains isolated from 55 diabetic foot ulcers. The subjects were selected from the 2465 patients with diabetes mellitus hospitalized in the Timişoara Diabetes Clinic, between 2011 and 2013. Germs’ identification relied on cultural and biochemical characteristics. Final identification and antimicrobial testing were performed using the Vitek 2 (Bio Merieux France) automatic analyzer. Results: All the 55 samples collected from diabetic foot ulcers were positive. We isolated 64 bacterial strains (some samples were positive for 2 microorganisms). The most frequently isolated germ was S. aureus, in 33 samples (51.56%). All these S. aureus strains showed resistance to benzylpenicillin, while only 33.33% were methicillin-resistant (MRSA). Conclusions: The most frequently isolated germ in the wound secretions from diabetic foot ulcers was S. aureus. The highest percentage of antimicrobial resistance was recorded to benzylpenicillin and erythromycin.

Association of traditional complementary and alternate medicine usage with quality of life of diabetic patients in a Malaysian tertiary hospital

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Chinedum Ogbonnaya Eleazu ◽  
Aniza Abd Aziz ◽  
Tay Chuu Suen ◽  
Lam Chun-Hau ◽  
Chin Elynn ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Diabetic Foot ◽  
Heart Diseases ◽  
Tertiary Hospital ◽  
Foot Ulcers ◽  
Diabetic Patients ◽  
Diabetic Foot Ulcers ◽  
Content Type ◽  
Significant Difference

Purpose This study aims to design to assess the traditional, complementary and alternate medicine (TCAM) usage and its association with the quality of life (QOL) of Type 2 diabetic patients in a tertiary hospital (Hospital Universiti Sains Malaysia) in Malaysia. Design/methodology/approach A total of 300 respondents included in this study were divided into the following two major categories: TCAM (34.33% of respondents) and non-TCAM users (65.67% of the respondents), respectively. The mean ages of the respondents were 59.3 ± 10.2 for the TCAM users and 57.7 ± 12.0 for the non-TCAM users. Findings A greater percentage of non-TCAM users reported poor control of diabetes (14.7%) and blood glucose (55.8%) compared with the TCAM users (9.7% and 48.5%, respectively). Further, the diabetic patients on TCAM reported lower rates of coma, stroke and kidney problems but higher rates of diabetic foot ulcers, heart diseases and retinopathy than the non-TCAM users. Additionally, the diabetic patients with TCAM usage had a significantly better physical (p = 0.02) and overall (p = 0.03) qualities of life compared to the non-TCAM users. However, psychological, social and environmental health did not show any significant difference. Originality/value The prevalence of TCAM usage among diabetic patients was lower than in other comparable studies. Diabetic patients on TCAM reported lower rates of coma, stroke and kidney problems but higher rates of diabetic foot ulcers, heart diseases and retinopathy than the non-TCAM users. Further, diabetes patients on TCAM reported better QOL compared to non-TCAM users especially in terms of physical health.

Application of a collagen matrix dressing on a neuropathic diabetic foot ulcer: a randomised control trial

2020 ◽  
Vol 29 (Sup3) ◽  
pp. S13-S18 ◽  
Author(s):  
Gholamreza Esmaeeli Djavid ◽  
Seyed Mehdi Tabaie ◽  
Siamak Bashardoust Tajali ◽  
Mehrangiz Totounchi ◽  
Amirreza Farhoud ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Wound Care ◽  
Healing Process ◽  
Collagen Matrix ◽  
Complete Healing ◽  
Randomised Control Trial ◽  
Control Group ◽  
Study Group ◽  
Number Of Patients

Objective: Diabetic foot ulcers (DFU) are often hard-to-heal, despite standard care. With such a complicated healing process, any advanced wound care to aid healing is recommended. Chitosan/collagen composite hydrogel materials have the potential to promote the regenerative process. In this study, the efficacy of a new collagen matrix dressing including chitosan/collagen hydrogel was compared with a standard dressing of saline-moistened gauze for wound healing in patients with a hard-to-heal neuropathic DFU. Method: This is an open labelled, randomised clinical trial. After conventional therapy consisting of debridement, infection control and offloading, patients were randomly allocated to receive either a collagen matrix dressing (the study group, receiving Tebaderm manufacturer) or a saline-moistened gauze dressing (control group) for wound care. The reduction in DFU size and the number of patients with complete healing were measured throughout the treatment and in follow-up. Results: A total of 61 patients with a neuropathic DFU were recruited. Average percentage reduction in DFU size at four weeks was greater in the study group compared with the control group (54.5% versus 38.8%, respectively). Rate of complete healing rate at 20-weeks' follow-up was significantly better in the study group than the control group (60% versus 35.5%, respectively). Conclusion: The collagen matrix dressing used in this study accelerated the healing process of patients with a hard-to-heal DFU. Further research may suggest the used of this dressing to shorten the length of time to achieve complete healing.

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