scholarly journals Neurodevelopmental outcome of very low birth weight and extremely low birth weight newborn at 12 months of corrected age associated with prenatal risk factors

2021 ◽  
Vol 8 (12) ◽  
pp. 1965
Author(s):  
Balai Chandra Karmakar ◽  
Kausik Patra ◽  
Mrinmoy Bairagi
Keyword(s):  
Risk Factors ◽  
Cerebral Palsy ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Extremely Low Birth Weight ◽  
Perinatal Infection ◽  
Prenatal Risk ◽  
Prenatal Risk Factors ◽  
Low Birth Weight Babies

Background: Various neuro-developmental impairment (NDI) among very low birth weight babies (VLBW) and extremely low birth weight (ELBW) babies are common in Indian scenario. This study was designed to assess the impact between prenatal risk factors and neuro-developmental outcomes of premature infants.Methods: This descriptive study was conducted on 143 VLBW and ELBW babies admitted in SNCU of North Bengal Medical College, Darjeeling, West Bengal and discharged babies were followed up.Results: Total 143 neonates were studied among male 82 (57.3%) and female 61 (42.7%) and AGA: SGA ratio was 1.97. Birth weight ranged from 500 to 1500grams with mean was 1199.6±244.14 and the median was 1240 gm. The mean gestational age (Mean± SD) was 29.65±2.032 weeks with range 24-32 weeks and the median was 30 weeks. 28 (19.6%) had PIH, 39 (27.3%) had multiple gestation, 18 (12.6%) had perinatal infection and 25 (17.5%) had birth asphyxia. CRIB II score ranged from 3-18 with mean was 8.021±3.883 and median was 7. 73.4% (105/143) were discharged alive. Significant positive correlations were found among birth weight, gestational age, perinatal infection (p<0.001). Adverse neonatal outcome was associated with CRIB II score ≥10. Total CRIB II score with parameters of NDI like developmental delay, cerebral palsy, visual abnormality, absent ABR showed good correlation (p<0.001). Fisher Exact test revealed significant association between total score and Cerebral palsy (p=0.0005), visual abnormality (p=0.0005), absent ABR (p=0.0002).Conclusions: Perinatal risk factors influence future NDI in very low and extremely low birth weight babies. They should be identified and treated promptly to achieve good outcome. 

scholarly journals Risk factors of cerebral palsy in the perinatal period

2016 ◽  
Vol 48 (3) ◽  
pp. 175
Author(s):  
Santi Gunarwati ◽  
S. Yudha Patria ◽  
Madarina Julia
Keyword(s):  
Risk Factors ◽  
Cerebral Palsy ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Premature Birth ◽  
Very Low Birth Weight ◽  
Univariate Analysis ◽  
Perinatal Period ◽  
Neonatal Seizure ◽  
Case Group

Background Cerebral palsy is an irreversible yet preventablecondition, thus it is necessary to know the risk factors of thedisease. The potential risk factors that are found in the perinataland neonatal period i.e. asphyxia, sepsis, very low birth weight,premature birth, and neonatal seizure. No available data for therisk factors of cerebral palsy in Indonesia.Objective To identify the perinatal risk factors in cerebral palsy.Methods We performed an age and sex-matched nested case-control study. The case group was children with cerebral palsywho were born at Sardjito Hospital during 1997-2005. The controlgroup was selected from the same population as the case group.Risk factors during the perinatal period consisted of asphyxia,sepsis, very low birth weight, premature birth and neonatal seizure.Logistic regression was used to determine the association betweenrisk factors and cerebral palsy.Results Univariate analysis showed that the following factors wererisk factors for cerebral palsy, i.e., asphyxia (OR 5.6, 95%CI 2.48;12.53); premature birth (OR 4.5; 95%CI 1.55; 13.13); and neona-tal seizure (OR 7.5, 95%CI 3.13; 18.03). On multivariate analysisrisk factors associated with cerebral palsy were asphyxia (aOR6.3, 95%CI 2.42; 16.66) and neonatal seizure (aOR 10.9,95%CI4.03; 29.97).Conclusion Asphyxia and neonatal seizure are significant riskfactors of cerebral palsy in perinatal period

scholarly journals Prevalence and Initial Diagnosis of Cerebral Palsy in Preterm and Term-Born Children in Taiwan: A Nationwide, Population-Based Cohort Study

2021 ◽  
Vol 18 (17) ◽  
pp. 8984
Author(s):  
Hsin-Hua Wang ◽  
Yea-Shwu Hwang ◽  
Chung-Han Ho ◽  
Ming-Chi Lai ◽  
Yu-Chin Chen ◽  
...  
Keyword(s):  
Cerebral Palsy ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Population Based ◽  
Initial Diagnosis ◽  
Extremely Low Birth Weight ◽  
Research Database ◽  
Preterm Children

The aim of this long-term longitudinal study in Taiwan was to estimate and compare the prevalence of cerebral palsy (CP) and to identify the age of CP diagnosis of term-born and preterm children with different birthweights. Records of 1494 extremely low birth weight (ELBW, <1000 g), 3961 very low birth weight (VLBW, 1000–1499 g), 19,612 low birth weight (LBW, 1500–2499 g) preterm, and 100,268 matched term-born children were retrieved from Taiwan′s National Health Insurance Research Database. According to a 12-year retrospective data review, the results showed the highest prevalence of CP in preterm ELBW children (147.3 cases per 1000 neonatal survivors), followed by preterm VLBW (97.2 cases), preterm LBW (27.7 cases), with the lowest prevalence in term-born children (2.5 cases). Regardless of the birthweight group, 90% of preterm children with CP were diagnosed by 4 years of age, but it was 7 years before 90% of term-born children with CP were diagnosed. After removing the children whose CP was caused by brain infections, injuries, or cerebrovascular accidents after 4 months of age, there were similar mean ages at the initial CP diagnosis (1.58–1.64 years of age) across birthweight groups born prematurely, but initial diagnosis occurred at an older age (2.41 years of age) in term-born children. The results indicate that birthweight is reversely correlated with the prevalence of CP in preterm children. Although the three preterm birthweight groups received different types of developmental follow-up programs after birth, it did not influence their age at the initial diagnosis of CP. Furthermore, we suggest that follow-up for at least 4 years after birth for preterm children, and 7 years for term-born children, is optimal for estimating CP prevalence. In order to identify and provide early intervention for term-born children with CP earlier, it is suggested that parents routinely fill out a self-reported motor developmental screening questionnaire and pediatricians conduct a motor developmental examination on term-born children at each time of scheduled vaccination injections.

scholarly journals Assess the Prevalence of Low-Birth-Weight Babies and Its Risk Factors among Postnatal Mothers in Wardha District

2021 ◽  
Vol 10 (36) ◽  
pp. 3094-3098
Author(s):  
Yugandhara Dilip Hingankar ◽  
Bali Thool ◽  
Vaishali Taksande
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Demographic Variables ◽  
Extremely Low Birth Weight ◽  
Descriptive Research ◽  
Adequate Knowledge ◽  
Prenatal Growth ◽  
Low Birth Weight Babies ◽  
Postnatal Mothers

BACKGROUND Babies of low birth weight (LBW) include 2,499 g or less weight as stated by WHO. LBW consists of VLBW which is below 1500 g and extremely low birth weight which is lesser than 1000 g. The normal gross weight of the infant at the time of delivery is 2500 - 4200 g. The cause of LBW is preterm birth or a slow prenatal growth rate. The survival rate is determined by the baby’s birth weight. Several risk factors are also associated such as multiple pregnancies, poor nutrition, hypertension, drug addiction or intake of alcohol. It is very necessary to prevent LBW rather than treating it after birth. The present study was done to assess the prevalence of lowbirth-weight babies and its risk factors among postnatal mothers in the Wardha district. METHODS A descriptive research design was undertaken, and 35 postnatal mothers in the Wardha district were selected for the study, the data was collected with the help of a structured questionnaire and a risk factor assessment scale was used for postnatal mothers. RESULTS The result of the study shows the prevalence rate of LBW babies among postnatal mothers as 49.18 %, and there was an assessment of risk factors among postnatal mothers from selected areas and association of prevalence of low birth with selected demographic variables. There was no association of prevalence of lowbirth-weight babies among postnatal mothers in relation to demographic variables. CONCLUSIONS This study concludes that there is a good prevalence of LBW babies but mothers didn’t have adequate knowledge regarding LBW of babies and risk factors that affect the mother as well as the foetus. KEY WORDS Low Birth Weight, Preterm, Gestation, Dehydration, Hyperthermia, Hypothermia

Risk factors for preterm labor. Immediate outcomes in very low and extremely low birth weight babies

2019 ◽  
Vol 22 (6) ◽  
pp. 70
Author(s):  
R. Kh. Shangareeva ◽  
O. A. Bryukhanova ◽  
A. I. Fatykhova ◽  
R. Kh. Bakhitova ◽  
Z. V. Maksimenko ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Preterm Labor ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Babies

scholarly journals A study on neurodevelopmental outcome and its associated risk factors in very low birth weight babies in a tertiary care teaching hospital in Kolkata

2016 ◽  
Vol 7 (5) ◽  
pp. 61-69
Author(s):  
Somen Sur ◽  
Subhasis Das ◽  
Soumitra Masani
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Very Low Birth Weight ◽  
Neurodevelopmental Outcome ◽  
Developmental Screening ◽  
Fine Motor ◽  
Low Birth Weight Babies

Background: Very low birth weight babies are very fragile in nature and usually undergone through stormy neonatal period, which affects significantly their neurodevelopmental outcome in long term basis.Aims and Objectives: 1. Assessment of neurodevelopmental outcome in very low birth weight (VLBW) babies at 12 month corrected gestational age. 2. Study of risk factors associated with such outcome.Materials and Methods: VLBW babies without any major congenital anomaly were included in this study. They were followed up in high risk clinic upto 12 month corrected gestational age. In follow up visits, assessment of tone was done by Amiel Tiesonmethod and 180 degree flip test. Developmental screening was done by Denver Developmental Screening Test (DDST II).Data obtained from this study were entered in Microsoft Excel and subsequently analysed with the help of Epi Info (TM) 3.5.3 software.Results: 24.4% among the study population showed neurodevelopmental abnormalities. Of them, 22.2% VLBW infants had muscle tone abnormality; 15.6% were suspect in gross motor development, 8.9% were suspect in fine motor, 11.1% were suspect in personal – social and 8.9% were suspect in language development, which were statistically significant. On assessment of risk factors, it was found that low birth weight, prematurity, non-use of antenatal corticosteroid, hypoglycaemia, intraventricular haemorrhage, sepsis, jaundice, mechanical ventilation, intra uterine growth retardation were significantly associated with various strata of neurodevelopmental outcome.Conclusion: VLBW babies are very prone to develop neurodevelopmental complications. Taking proper care regarding above said risk factors can reduce such complications. Also these babies should follow up properly to detect complication/s at earliest, and take “early intervention’’ steps.Asian Journal of Medical Sciences Vol.7(5) 2016 61-69

scholarly journals Anthropometric outcome of extremely low birth weight and very low birth weight newborn at 12 months of corrected age associated with prenatal risk factors

2019 ◽  
Vol 6 (6) ◽  
pp. 2242
Author(s):  
Balai Ch. Karmakar ◽  
Ramesh Ch. Kalder
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Head Circumference ◽  
Extremely Low Birth Weight ◽  
Perinatal Risk Factors ◽  
Perinatal Risk ◽  
Low Birth Weight Babies ◽  
The Mean ◽  
Weight For Age

Background: Advancement of skill, technology and perinatal medicine has led to improve survival of low birth weight babies during the last few decades but they have reported high incidence of growth failure during infancy and early childhood. The objective of the study was to find out the influence of perinatal risk factors on anthropometric outcome.Methods: A prospective cohort study conducted on 143 ELBW and VLBW babies admitted in Sick Newborn Care Unit (SNCU and PICU) of North Bengal Medical College and Hospital (NBMC), Darjeeling, West Bengal from 2016 to 2017 and discharged babies were followed up.Results: Total 143 neonates were studied at NBMC among male 82(57.3%) and female 61(42.7%), 95 were AGA and 48 were SGA babies. Significant positive correlations were found among birth weight, gestational age, perinatal infection (p<0.001). The mean weight for age (Mean±SD) was 7.615±1.1092 kg with median 7.8 kg. The mean length for age (Mean±SD) was 72.6±3.74 cm with median 73 cm. The mean head circumference for age (Mean±SD) was 42.5±2.12 cm median 43 cm. Adverse neonatal outcome associated with CRIB II score ≥10. Total CRIB II score with parameters of growth (<-2 Z score) like weight for age, length for age, weight for length and head circumference for age shows significant correlation (p<0.001).Conclusions: Perinatal risk factors are important determinant for future anthropometric outcome in very low and extremely low birth weight babies. They should be identified, and appropriate measures should be taken to achieve good outcome.

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