scholarly journals A study to assess the association of various factors of adherence to treatment on the tuberculosis treatment outcome among new sputum smear positive pulmonary tuberculosis patients under Revised National Tuberculosis Control Programme in Bengaluru area

2019 ◽  
Vol 6 (10) ◽  
pp. 4344
Author(s):  
Ramya M. S. ◽  
Jyothi Jadhav ◽  
Ranganath T. S.
Keyword(s):  
Treatment Outcome ◽  
Alcohol Intake ◽  
Control Programme ◽  
Sputum Smear ◽  
Lower Socioeconomic Status ◽  
Tb Treatment ◽  
Lower Socioeconomic ◽  
Tuberculosis Control Programme ◽  
National Tuberculosis ◽  
Cure Rates

Background: Tuberculosis (TB) is a top infectious disease killer worldwide. In India although Revised National Tuberculosis Control Programme (RNTCP) has seen significant success in TB treatment, patient non-adherence or lost to follow up continue to persist and are influenced by various factors. The present study aims to know the influence of adherence factors on TB treatment outcome among new sputum smear positive (NSSP) pulmonary TB patients under RNTCP. The objectives of the present study were to describe the distribution of socio-demographic factors, outcome patterns among NSSP patients and to assess the association of various adherence factors on TB-treatment outcome among NSSP patients.Methods: A prospective longitudinal study among 149 NSSP patients from selected TU’s of Bengaluru.Results: Among the 149 NSSP patients 107 (72%) were males and 42 (28%) were females. Treatment outcome is categorized as cured (120) and other treatment outcomes (defaulted-17 or treatment failure-3 or died-9). Among the various socio-demographic and adherence-factors: age >50years, illiteracy, male-gender, Hindu-religion, lower socioeconomic-status, poor-patient knowledge about TB, disbelief in TB-treatment, unwillingness to continue treatment with subsiding symptoms, smoking, alcohol intake, presence of diabetes or hypertension or COPD or HIV, patient’s un-satisfaction with treatment-availability or accessibility or contact-timings, no-encouragement from family members, other marital status and absence of stigma showed lower cure rates. Of these factors illiteracy, lower socioeconomic-status, poor patient’s knowledge on tuberculosis, smoking, alcohol intake, HIV positive status, un-satisfaction with TB-treatment availability and other marital-status showed statistical significance on the TB treatment outcome.Conclusions: With the observed associations of the above factors on TB-treatment outcome, Further measures like improving patient’s knowledge on tuberculosis, health-services and patient-provider relationship; appropriate TB-HIV care and encouragement to quit smoking or alcohol intake, could improve TB-treatment cure rates. 

scholarly journals Impact of drug susceptibility on treatment outcome in sputum smear positive pulmonary tuberculosis patients receiving category-II regimen in RNTCP under field conditions in an urban setting

2018 ◽  
Vol 5 (3) ◽  
pp. 561
Author(s):  
Ramesh P. M. ◽  
Saravanan M.
Keyword(s):  
Treatment Outcome ◽  
Drug Susceptibility ◽  
Control Programme ◽  
Male Dominance ◽  
Urban Setting ◽  
Sputum Smear ◽  
National Tuberculosis ◽  
Smear Positive Pulmonary Tuberculosis ◽  
Mdr Tb ◽  
Pre Treatment

Background: The study was conducted with the aim to evaluate the pre-treatment drug susceptibility profile and to assess the influence of drug resistance on treatment outcome among patients treated with category- II (cat- II) regimen under programme conditions.Methods: This study was conducted on 58 smear positive patients with history of previous anti-tuberculosis treatment for more than one month, comprising cases of ‘Failure’, ‘Treatment after Default’ (TAD) and ‘Relapse’. They received cat- II regimen in Chennai Corporation, RNTCP (revised National tuberculosis control programme) centers from July 2006 to September 2006 and they were monitored upto July 2007 as per RNTCP guidelines to assess the outcome of cat-II treatment by sputum smear status.Results: Male dominance (n=40) was seen in the study participants. Most common age group affected was 35-44 years (n=20). Out of 57 cases, 50.9% cases come under ‘Relapse’, 26.3% arises from ‘TAD’ and 22.8% cases were from ‘Failure’. After completion of treatment with cat-II regimen, out of 57 patients 33 patients were cured and 11 cases were into the category of failure, 10 patients were defaulted during treatment and 3 were died.Conclusions: Besides, the low treatment efficiency in MDR-TB cases, cat- II regimen was effective in sensitive and INH resistant cases.

scholarly journals Evaluation of revised national tuberculosis control programme in rural Puducherry

2019 ◽  
Vol 6 (9) ◽  
pp. 3842
Author(s):  
Surendar Rangasamy ◽  
Arthi Marimuthu ◽  
Rajkumar Subramanian ◽  
Narayan K. A.
Keyword(s):  
Alcohol Intake ◽  
Economic Status ◽  
Compliance Rate ◽  
Control Programme ◽  
Tuberculosis Control ◽  
National Tuberculosis Control Programme ◽  
Therapy Strategy ◽  
Tuberculosis Control Programme ◽  
National Tuberculosis ◽  
National Tuberculosis Control

Background: WHO estimates that annually 3 million deaths occurs due to tuberculosis and will reach to more than one billion in 2020. In India, more than 40% of population is infected. The revised national tuberculosis control programme (RNTCP) uses directly observed treatment, short-course (DOTS) therapy strategy to reduce mortality and morbidity, reduce transmission. Compliance to DOTS therapy is one of the important factors that affect the treatment outcome. Hence this study was done to assess the drug compliance rate of adults registered under RNTCP in the past one year and first three months after starting the study and to explore the factors associated with drug compliance.Methods: A longitudinal study was done in Bahour Commune Panchayat with subjects registered under RNTCP from January 2011 to March 2012. They were followed-up by house visit, interviewed using a semi-structured questionnaire.Results: The mean age was 44±13 years, 35 (68.6%) males were illiterate. About 60 (85.7%) belong to Class IV socio-economic status; 15 (29.4%) and 33 (64.7%) of adults had smoking and alcohol intake respectively; 03 (04.3) were diabetic. The treatment compliance rates were cured 64.3% (45/70), completed 27.1% (19/70), default 2.9% (02/70), failure 5.7% (04/70).Conclusions: Male being diseased in the productive age-group, will not only affect the health of the patient but also affect the family’s economic status. Most of the males gave history of alcohol intake, for which they require constant motivation for compliance to the treatment.

scholarly journals Study of socio-demographic and treatment profile and other epidemiological correlates of clients attending revised national tuberculosis control programme clinic in a tertiary hospital of West Bengal, India

2020 ◽  
Vol 7 (2) ◽  
pp. 742
Author(s):  
Subha Sankha Kundu ◽  
Rajib Sikder ◽  
Rituraj Dey ◽  
Kunal Kanti Majumdar ◽  
Gautam Joardar
Keyword(s):  
Tertiary Hospital ◽  
Control Programme ◽  
Sputum Smear ◽  
Medical College ◽  
Tuberculosis Control Programme ◽  
Short Course ◽  
The World ◽  
National Tuberculosis ◽  
Directly Observed Treatment ◽  
Treatment Profile

Background: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis bacteria spread by droplet infection.According to global TB report 2017, there were approximately 28 lakhs cases of TB in India accounting a quarter of the world TB cases. Today, it is the fastest-expanding and the largest program in the world in terms of patients initiated on treatment and the second largest in terms of population coverage. The objective of this study is to assess the socio-demographic profile of the patients attending revised national TB control programme (RNTCP) clinic, to determine the nature of disease, its co-morbidities, seasonal variability and treatment profile of the patients attending the RNTCP clinic during this study period.Methods: This was a retrospective record-based study conducted in RNTCP clinic of KPC Medical College and Hospital, Kolkata. Details of all the 684 patients who were enrolled under RNTCP from the year 2014 to 2018 were collected from RNTCP records. Data was analyzed using suitable software.Results: 684 cases were registered and treated under directly observed treatment, short-course (DOTS) during the study period with 41% completing treatment. 84.3% were new TB cases. 23.61% were sputum smear positive. Males (67.25%) contributed to more in cases. Maximum patients visited during March to June. 74.87% of the total patients were diagnosed with pulmonary TB. Pleural effusion was the commonest form of extrapulmonary TB (42.75%).Conclusions: The number of TB cases showed a decreasing trend over the years. Males contributed to a greater number of cases with majority being contributed by the age group 21-30 years.

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