scholarly journals Role of plasma ascorbic acid in nasal allergy- a review

2020 ◽  
Vol 7 (10) ◽  
pp. 4193
Author(s):  
Manish Munjal ◽  
Atul Singh ◽  
Ajit Singh Khurana ◽  
Shubham Munjal ◽  
Arnav Mehta ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Ascorbic Acid ◽  
Redox Potential ◽  
Adaptive Immunity ◽  
Common Cold ◽  
Pivotal Role ◽  
Nasal Allergy ◽  
Plasma Ascorbic Acid ◽  
Innate And Adaptive Immunity

Ascorbic acid plays a pivotal role in common cold and allergic rhinitis by affecting the innate and adaptive immunity It antagonizes mediators of allergic rhinitis like histamine, prostaglandins etc. It also maintains the normal redox potential of the cells preventing bonding of antibody to antigen. It helps in stress conditions and has stimulatory effect on interferon synthesis. The present study was undertaken to study the role of plasma ascorbic acid in patients suffering from nasal allergy.

scholarly journals Pivotal Role of Innate and Adaptive Immunity in Anthracycline Chemotherapy of Established Tumors

2011 ◽  
Vol 71 (14) ◽  
pp. 4809-4820 ◽  
Author(s):  
Stephen R. Mattarollo ◽  
Sherene Loi ◽  
Helene Duret ◽  
Yuting Ma ◽  
Laurence Zitvogel ◽  
...  
Keyword(s):  
Adaptive Immunity ◽  
Pivotal Role ◽  
Innate And Adaptive Immunity ◽  
Anthracycline Chemotherapy

scholarly journals Plasma ascorbic acid therapy and eosinophilic counts in allergic rhinitis: a pilot study

2020 ◽  
Vol 7 (1) ◽  
pp. 126
Author(s):  
Manish Munjal ◽  
Atul Singh ◽  
Shubham Munjal ◽  
Indu Verma ◽  
Abhra Ghosh ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Ascorbic Acid ◽  
Vitamin C ◽  
Care Facility ◽  
Health Care Facility ◽  
Plasma Ascorbic Acid ◽  
Acid Therapy ◽  
The Mean ◽  
And Control

<p class="abstract"><strong>Background:</strong> Role of plasma ascorbic acid in reducing the eosinophilic counts in subjects of allergic rhinitis was studied.</p><p class="abstract"><strong>Methods:</strong> 60 patients were randomly selected from the Rhinology clinics of Oto- Rhino- laryngology and Head-Neck services of a tertiary health care facility. Shift in the eosinophilic counts in three groups of patients i.e., allergic rhinitis, placebo and control groups was analyzed and compared. The study was undertaken in a period of 1<sup>1/2</sup> years (June 2009 -January 2010) Blood eosinophilic count as %age of DLC was noted.</p><p class="abstract"><strong>Results:</strong> The mean eosinophilic count was elevated in allergic patients (8.009±2.91) with respect to that in the controls (4.70±1.26). It reverted to normal with treatment with vitamin C. No change was seen in the placebo group. (5.45±3.56).</p><p class="abstract"><strong>Conclusions:</strong> Vitamin-c reduces the eosinophilic counts in allergic rhinitis.</p><p> </p>

ROLE OF INNATE AND ADAPTIVE IMMUNITY ON ATHEROSCLEROSIS IN SUBJECTS WITH FAMILIAL HYPERCHOLESTEROLEMIA

2019 ◽  
Vol 73 (9) ◽  
pp. 1867
Author(s):  
Maria Cristina Izar ◽  
Waleria Fonzar ◽  
Francisco Fonseca ◽  
Henrique Fonseca ◽  
Tuany P. Silva ◽  
...  
Keyword(s):  
Familial Hypercholesterolemia ◽  
Adaptive Immunity ◽  
Innate And Adaptive Immunity

scholarly journals Sexual dimorphism in immune function: The role of sex steroid hormones

2018 ◽  
Vol 51 ◽  
pp. 02007
Author(s):  
Anna Mihailova ◽  
Indrikis Krams
Keyword(s):  
Immune System ◽  
Sexual Dimorphism ◽  
Infectious Diseases ◽  
Immune Function ◽  
Steroid Hormones ◽  
Adaptive Immunity ◽  
Gonadal Hormones ◽  
Sex Steroid ◽  
Innate And Adaptive Immunity

There is evidence of the relation of sex steroid hormones and sexual dimorphism in immune system response to infectious diseases. The aim of this review was to identify the role of sex hormones in immune function and sexual dimorphism of immune reactions. Gonadal hormones together with the immune system play an important role in process of immune responses to the disease [1]. Estrogens, progesterone and testosterone have different impacts on immune cells and different gonadal hormones are of high importance for responses of innate and adaptive immunity [1, 2]. Estrogens mainly enhance immune function while testosterone has a suppressive role. Higher progesterone during pregnancy leads to autoimmune disease remission and an elevated susceptibility toward certain infectious diseases [2, 3, 4]. The intensity and prevalence of viral infections are typically higher in males, whereas disease outcome could be worse for females [5]. Sexual dimorphism of immune function is based on different concentrations of sex hormones in males and females and on a specific mediating role of these hormones in immune function and response along with differences in innate and adaptive immunity.

scholarly journals Role of IL-5 in Innate and Adaptive Immunity to LarvalStrongyloides stercoralisin Mice

2000 ◽  
Vol 165 (8) ◽  
pp. 4544-4551 ◽  
Author(s):  
De’Broski R. Herbert ◽  
James J. Lee ◽  
Nancy A. Lee ◽  
Thomas J. Nolan ◽  
Gerhard A. Schad ◽  
...  
Keyword(s):  
Adaptive Immunity ◽  
Innate And Adaptive Immunity

scholarly journals The Role of Innate and Adaptive Immunity in Parkinson's Disease

2013 ◽  
Vol 3 (4) ◽  
pp. 493-514 ◽  
Author(s):  
George T. Kannarkat ◽  
Jeremy M. Boss ◽  
Malú G. Tansey
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Adaptive Immunity ◽  
Innate And Adaptive Immunity

The Role of Leukotrienes in Nasal Allergy

2003 ◽  
Vol 129 (3) ◽  
pp. 274-279 ◽  
Author(s):  
Ilknur Haberal ◽  
Jacquelynne P. Corey
Keyword(s):  
Allergic Rhinitis ◽  
Work Performance ◽  
Respiratory Infections ◽  
Nasal Congestion ◽  
Comorbid Condition ◽  
Nasal Allergy ◽  
Upper Airways ◽  
School Work ◽  
Asthma Patients

OBJECTIVE: This review focuses on the role of cysteinyl leukotrienes (cysLTs) in nasal allergy. The purpose was to provide knowledge of the role of cysLTs in the pathophysiology of nasal allergy and the role of antileukotrienes in the treatment of nasal allergies. MATERIALS AND METHODS: We conducted a literature review. RESULTS: The proinflammatory effects of cysLTs have been well described in asthma. Antileukotrienes have proved to be an effective anti-inflammatory treatment for asthma patients. Similar to pathogenesis of asthma, cysLTs exert potent inflammatory effects in the upper airways and play a role in the pathogenesis of allergic rhinitis and other nasal allergies. CONCLUSION: Antileukotriene treatment appears to be beneficial in nasal allergies. Allergic rhinitis is a complex, IgE-mediated inflammatory disease of the upper airways. It is the most common allergic disease, occurring in 10% to 30% of adults and up to 30% of children. It may be perennial or seasonal. Sneezing, itching, watery rhinorrhea, and nasal obstruction are classic symptoms. It may impair cognition, school/work performance and productivity, behavior, mood, and quality of life. On physical examination, clear secretions, nasal congestion, pink-bluish nasal mucosa, the allergic salute, and allergic shiners may be detected. Allergic rhinitis is a common comorbid condition with asthma, sinusitis, otitis media, nasal polyposis, and respiratory infections.

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