scholarly journals Adherence of Option B+ prevention of mother-to-child transmission program and its associated factors among pregnant and lactating mothers in public health facilities of East Gojjam zone, Amhara region, Ethiopia, 2017

2019 ◽  
Vol 5 (10) ◽  
pp. 301 ◽  
Author(s):  
Yezina Demelash ◽  
Nurilign Abebe ◽  
Yewbmirt Sharew ◽  
Tsegaye Mehare
Keyword(s):  
Public Health ◽  
Associated Factors ◽  
Health Facilities ◽  
Pmtct Program ◽  
Mother To Child Transmission ◽  
Amhara Region ◽  
Child Transmission ◽  
Public Health Facilities ◽  
Lactating Mothers ◽  
Mother To Child

<p class="abstract"><strong>Background:</strong> Adherence of antiretroviral treatment (ART) among women on prevention of mother-to-child transmission (PMTCT) program is a central component to reduce viral loads and achieve elimination of mother to child transmission of human immunodeficiency virus (HIV) to Ethiopia. Option B+ PMTCT program is a recently introduced approach to eliminate new HIV infection among child. There is limited evidence on the drug adherence of women on ART in the Option B+ strategy. The aim was to assess adherence of Option B+ PMTCT drug and its associated factors among pregnant &amp; lactating mothers in health facilities of East Gojjam zone, Amhara, Ethiopia, 2017.</p><p class="abstract"><strong>Methods:</strong> Institution based cross-sectional study design was conducted from randomly selected three public health facilities in East Gojjam zone. Data was entered in to Epi data 3.1 and cleared then transferred to SPSS version 20 for analysis. To assess the associated factors, logistic regression model was employed. A p value &lt;0.05 was considered statistically significant.  </p><p class="abstract"><strong>Results:</strong> Adherence on Option B+ PMTCT drug was 75%. The likelihood of being adherence found to be significant association with the following variables: Mother’s educational status (AOR=2.03; 95%CI: 1.465, 8.918), partner occupation (AOR=4.73; 95%CI: 1.12, 19.87), time to reach to health facility (AOR=0.21; 95%CI: 0.05, 0.824), and maternal HIV knowledge (AOR=0.13; 95%CI: 0.03, 0.44).</p><strong>Conclusions:</strong> Adherence to Option B+ PMTCT drug in East Gojjam zone, Amhara region was low compared to the national goal. Effort should be made both governmentally as well as non- governmentally to advance the knowledge about Option B+ PMTCT program so as to improve the long term maternal and child health.

scholarly journals Loss to Follow-Up among HIV Positive Pregnant and Lactating Mothers on Lifelong Antiretroviral Therapy for PMTCT in Rural Uganda

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Matilda Kweyamba ◽  
Esther Buregyeya ◽  
Joy Kusiima ◽  
Vianney Kweyamba ◽  
Aggrey David Mukose
Keyword(s):  
Health Facilities ◽  
Hiv Positive ◽  
Peer Educators ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Loss To Follow Up ◽  
Lactating Mothers ◽  
Lost To Follow Up ◽  
Mother To Child

Background. Mother-to-Child Transmission of HIV accounts for more than 90% of all pediatric HIV infections. However, Prevention of Mother-to-Child Transmission (PMTCT) of HIV through provision of lifelong ART to HIV positive mothers faces various challenges which affect its success. One of such challenges is the loss to follow-up (LTFU) of mothers. Methodology. We conducted a cross-sectional study utilizing both quantitative and qualitative data collection methods. We were able to trace 279 HIV positive, pregnant, and lactating mothers among mothers who were initiated on lifelong ART for PMTCT in public health facilities in Ntungamo district, Western Uganda. The proportion of those who were lost to follow-up was determined, and Log binomial regression with stepwise backward elimination method was employed to identify factors associated with LTFU. Focus group discussions (FDGs) of women on lifelong ART and key informant interviews (KIIs) of peer educators were also performed. Results. Out of the 279 mothers that were successfully traced and interviewed, 103 (37%) were identified as lost to follow-up. The prevalence of LTFU was higher among those whose transport costs were above $2.75, adj (adjusted) PR (Prevalence Ratio) 1.6 (95% CI; 1.02-2.55); those who waited beyond one hour before being attended to, adj PR 1.74 (95% CI; 1.02-2.96); and those who assumed that their infant was already infected, adj PR 1.76 (95% CI; 1.15-2.70). On interviews, LTFU in these mothers was attributed to fear of swallowing antiretroviral drugs, HIV related stigma and discrimination, inadequate facilitation of the peer educators, long patient waiting time, and transportation to the health facilities. Conclusion. More than one-third of mothers initiated on lifelong ART for PMTCT in Ntungamo district were lost to follow-up over a period of 25 months. Recommendations. Provision of regular and adequate pre-ART and ART adherence counseling and provision of routine health education would reduce LTFU.

scholarly journals Level of adherence to option B plus PMTCT and associated factors among HIV positive pregnant and lactating women in public health facilities of Hawassa city, Southern Ethiopia

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0255808
Author(s):  
Samuel Abdisa ◽  
Zelalem Tenaw
Keyword(s):  
Public Health ◽  
Associated Factors ◽  
Health Facilities ◽  
Southern Ethiopia ◽  
Hiv Positive ◽  
P Value ◽  
Child Transmission ◽  
Adherence Level ◽  
Lactating Women ◽  
Public Health Facilities

Background Adherence to antiretroviral therapy is very essential to achieve a great outcome of drugs via suppressing viral load, preventing multidrug resistance, and reducing mother to a child transmission rate of the Human Immune Virus. Objective This study aimed to assess the level of adherence to option B plus PMTCT and associated factors among HIV Positive pregnant and lactating women in public health facilities of Hawassa city, Southern Ethiopia, 2020 G.C. Methods Institution-based cross-sectional study was done on 254 HIV-positive pregnant and lactating women attending the prevention of mother-to-child transmission (PMTCT) follow-up. Participants were selected by simple random sampling. Data collected through a structured interviewer-administered questionnaire were cleaned and entered into Epi-data 3.1 and exported to SPSS 20 for statistical analysis. Descriptive analysis was done. Bivariable and multivariable logistic regressions were done to measure the strength of association between independent and dependent variables using the odds ratio and 95% of confidence interval. A p-value <0.05 was taken as statistically significant. Result The overall adherence level to option B+ was 224 (88.2%). Respondents in age group of ≤ 25 [AOR = 0.12, 95% CI (0.03, 0.42)], with no formal education [AOR = 0.12, 95% CI (0.03, 0.51)], experienced drug side effects [AOR = 0.11, 95% CI (0.04, 0.32)], have good knowledge of PMTCT [AOR = 3.6, 95% CI (1.16, 11.3)], and get support from partner/family [AOR = 4.5, 95% CI (1.62, 12.4)] were identified associated factors with adherence level. Conclusion The level of adherence to option B plus PMTCT was 88.2% which is suboptimal. Ages, educational level, knowledge on PMTCT, getting support from partner/family, and drug side effect were significantly associated with adherence. Therefore, educating and counseling on the service of PMTCT to improve their knowledge and encouraging partner/family involvement in care are mandatory to achieve the standard adherence level.

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