scholarly journals Clinical profile of cases of dysphagia presenting in ENT department: a study from rural tertiary care center

2017 ◽  
Vol 3 (3) ◽  
pp. 639
Author(s):  
Ginni Datta ◽  
Manish Gupta ◽  
Naiya Rao
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Clinical Problem ◽  
Needle Aspiration ◽  
Clinical Profile ◽  
Barium Swallow ◽  
Tertiary Care Centre ◽  
Predominant Symptom ◽  
Alarm Symptom ◽  
A Prospective Study

<p class="abstract"><strong>Background:</strong> Swallowing is a complex motor reflex requiring coordination among the neurologic system and muscles of the oropharynx and oesophagus. Disorders both benign and malignant may interfere with the process and cause dysphagia. We hereby undertake a study in a rural tertiary care centre to study the clinical profile of cases of dysphagia and to find the relative incidence of various etiologies of dysphagia.</p><p class="abstract"><strong>Methods:</strong> A prospective study was conducted upon both out and indoor patients coming to Department of Otorhinolaryngology from January 2016 to January 2017 with predominant symptom of difficulty in swallowing for both solids, liquids or either. Detailed history &amp; examination was done. Further endoscopy, barium swallow, fine needle aspiration cytology (FNAC) &amp; biopsies were done as required. A total of 140 cases were taken into consideration.  </p><p class="abstract"><strong>Results:</strong> The mean age was 52.5 years with 60% patients males and 40% females. The commonest etiology of dysphagia was Gastroesophageal reflux disease (GERD) occupying 28.57%of cases. Among them 65% werefemales majority in the age group of 45-55 years. The 2<sup>nd</sup> common cause of dysphagia was growth pharynx 18.5% of cases. Among them 19 cases were diagnosed as growth oropharynx and 7 cases as growth supraglottis extending to hypopharynx. 88.46% were males and all were smokers. The 3<sup>rd</sup> common etiology of dysphagia was obstructive oesophageal causes which included oesophageal malignancies, oesophageal webs, strictures and diverticula in the frequency of 16%, 3%, 3% and 6% respectively. Oesophageal malignancies were mainly adenocarcinoma, all males who were chronic smokers.</p><p><strong>Conclusions:</strong> Dysphagia is a commonly encountered clinical problem &amp; limited studies exist regarding the prevalence of dysphagia etiologies. It is an alarm symptom, malignancy should be ruled out, and warrants early intervention. </p>

scholarly journals Descriptive study of clinical profile and outcome in patients of acute on chronic liver failure, at a tertiary care center in Northern India

2020 ◽  
Vol 7 (11) ◽  
pp. 1687
Author(s):  
Rakesh Kumar ◽  
Vandana Rana ◽  
Varghese Koshy ◽  
Vandana Gangadharan ◽  
George Koshy
Keyword(s):  
Liver Failure ◽  
Care Center ◽  
Tertiary Care ◽  
Descriptive Study ◽  
Chronic Liver ◽  
Clinical Profile ◽  
Chronic Liver Failure ◽  
Tertiary Care Centre ◽  
Female Ratio ◽  
Common Cause

Background: Acute-on-chronic liver failure (ACLF) is a recently described syndrome that is characterized by abrupt deterioration in patients with chronic liver disease (CLD) and has high short-term mortality. The aim of this study was to describe the clinical profile, causes and outcomes of ACLF at a tertiary care centre in Northern India.Methods: In this descriptive study of 50 consecutive patients, were included, between August 2015 to January 2018, who were admitted and diagnosed as ACLF as defined by APASL. Causes of acute precipitating event and CLD and outcomes were assessed.Occurrence and severity of organ failure was also assessed.Results: 48 (96 %) were males and 2 (4%) were females with male to female ratio was 24:1. The mean age of male and female subjects was similar, 40.7±9.9 years and 39.2±9.4 years respectively. The most common cause of CLD was alcohol in 50% cases and next most common cause was hepato-tropic viruses HBV infection in 20%, HCV in 6% cases and there was unknown cause in 12 % cases. The most common precipitating factor of acute decompensation was alcohol in 50% cases, hepatotropic viruses in 30% cases. Excluded sepsis and GI bleed as precipitating events. The combined mortality at the end of 1-month and 3-months, in our study was 60%. CLIF-SOFA score was found to be the most reliable scoring system to discriminate between survivors and non survivors. Conclusions: Alcohol was the commonest precipitating cause of ACLF. Organ failures (OFs) are independently predictive of mortality.

scholarly journals Clinical profile of rhinosporidiosis in a tertiary care center of an endemic area

2018 ◽  
Vol 4 (3) ◽  
pp. 659 ◽  
Author(s):  
Suneer R. ◽  
Sivasankari L.
Keyword(s):  
Tamil Nadu ◽  
Endemic Area ◽  
Histopathological Examination ◽  
Care Center ◽  
Tertiary Care ◽  
Granulomatous Inflammation ◽  
Clinical Profile ◽  
Medical College ◽  
Male Preponderance ◽  
A Prospective Study

<p class="abstract"><strong>Background:</strong> Rhinosporidiosis is a chronic granulomatous inflammation caused by <em>Rhinosporidium seeberi</em>. It is water borne disease endemic in Kanyakumari district of South India. The objective of the study was to study the clinical profile of rhinosporidiosis in an endemic area of Kanyakumari district</p><p class="abstract"><strong>Methods:</strong> This is a prospective study of 50 surgically treated cases of rhinosporidiosis carried out in the department of ENT, Kanyakumari Government Medical College from January 2016 to December 2017. All were diagnosed on clinical basis and were treated by excision and electrocautery of the base. The specimens were sent for histopathological examination.  </p><p class="abstract"><strong>Results:</strong> The cases in this study were in the age group between 6 to 70 years. Of these 38 were males and 12 were females indicating a male preponderance. The main presenting symptom was epistaxis in about 80% cases. Nose is the common site involved. Extra nasal spread is common in recurrent cases.</p><p class="abstract"><strong>Conclusions:</strong> The study reflects the endemicity of this disease in Kanyakumari district of Tamil Nadu. High incidence is noted in those bathing in ponds. Extra nasal spread is common in recurrent cases and raising health awareness will go a long way in decreasing its incidence.</p><p class="abstract"> </p>

Clinical profile in chronic meningitis patients: A prospective study at tertiary care center

2019 ◽  
Vol 10 (1) ◽  
pp. 52-53
Author(s):  
Kapil Shesherao More ◽  
◽  
Aruna Kondibarao Pohare ◽  
Avinash . ◽  
◽  
...  
Keyword(s):  
Prospective Study ◽  
Care Center ◽  
Tertiary Care ◽  
Clinical Profile ◽  
Tertiary Care Center ◽  
Chronic Meningitis ◽  
A Prospective Study

Study of Hemoptysis in a Tertiary Care Center of Province 1: Causes and Recurrences

2020 ◽  
Vol 5 (2) ◽  
pp. 1050-1054
Author(s):  
Ram Hari Ghimire ◽  
Ashima Ghimire ◽  
Rupesh Kumar Shreewastav ◽  
Sushil Yadav ◽  
Bidesh Bidesh Bista
Keyword(s):  
Diagnostic Yield ◽  
Care Center ◽  
Tertiary Care ◽  
Clinical Profile ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Number Of Patients ◽  
Chest Clinic ◽  
Telephone Calls

Introduction: Hemoptysis is a common but distressing and alarming symptom in a patient. Data related to detail clinical profile and follow up study of hemoptysis are lacking. Objective: This study was carried out to see the clinical profile of patients with hemoptysis and to study the recurrences in tertiary care centre of province 1 within the study period. Methodology: This was a prospective observational study conducted at the department of Pulmonary, Critical Care and Sleep Medicine of Nobel Medical College and Teaching Hospital, Biratnagar, Nepal. The study was carried out between 30th January 2017 to 1st February 2020. For follow up of recurrences of hemoptysis, the patients were asked for regular chest clinic follow up and regular telephone calls made to the patients, in case, patients could not attend the chest clinic for any reason. Results: A total of 150 patients were enrolled over the last 3 years. Among them 75% were male. The maximum number of patients (27%) were between 31-40 years of age group. Old sequelae of pulmonary tuberculosis (PTB) (32%) and bronchiectasis (28%) were the commonest cause of hemoptysis. Lung cancer (10%) and active PTB (10%) were other causes of hemoptysis. CT scan of the chest provided the highest (84%) diagnostic yield. Most of the cases were having mild hemoptysis (50%). 17% of the patients in our study had recurrences of hemoptysis. Conclusion: Old PTB sequelae with bronchiectasis (fibrobronchiectasis) were the commonest cause of hemoptysis. Conservative management worked most effectively in controlling hemoptysis, if used properly.

scholarly journals Clinical profile and outcome of multisystem inflammatory syndrome in children in a tertiary care centre of North Kerala: a prospective study

2021 ◽  
Vol 8 (12) ◽  
pp. 1972
Author(s):  
Naveena Sajeevan ◽  
Mohammed Manakkatt T. P. ◽  
Kavitha Pavithran ◽  
Urmila Muraleekrishnan K. V.
Keyword(s):  
Tertiary Care ◽  
Cervical Lymphadenopathy ◽  
Oral Prednisolone ◽  
Clinical Profile ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Methyl Prednisolone ◽  
Lv Dysfunction ◽  
A Prospective Study ◽  
Inflammatory Syndrome

Multisystem inflammatory syndrome in children (MIS-C) is a newly emerged disease following the outbreak of COVID-19. The nomenclature is given by WHO. Similar condition is named as paediatric inflammatory multisystem syndrome-temporally associated with SARS-CoV2 virus (PIMS-TS), by RCPCH. To study the clinical profile and outcome of MIS-C in 2 months to 18 years old. The 25 children, admitted in PICU and pediatrics ward were included in the study. The 79% required PICU admission and two required mechanical ventilation. One child expired. Children presented with conjunctival congestion (53%), diarrhoea (47%), cervical lymphadenopathy (37%), shock (31.5%), vomiting (36.8%), rashes (36.8%), mucosal erythema (36.8%), cough (10.5%) and headache (10.5%). Inflammatory markers were elevated in all the children. On initial echocardiography, 4 children (21%) had LV dysfunction with LVEF <50%. Six children (31.5%) were treated with IVIG and IV methylprednisolone, changed to oral prednisolone after 3 days and continued for 2 weeks. Three children (18%) were treated with IVIG and oral prednisolone. Two children (12%) were treated with IVIG alone. Eight children (47%) were treated with methylprednisolone alone. The median duration of hospitalisation was 5 days. 18 children (94.7%) were discharged to home within one week of admission. One 8 months old baby presented with shock, succumbed to death in spite of giving IV methyl prednisolone and IVIG. In our study we observed that early diagnosis and treatment with IVIG or steroids offers good outcome for the condition. Of the 19 children studied, 17 children were discharged within one week.

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