Ozone discolysis in lumbar disc prolapse

Background: Treatment of low back ache due to prolapsed intervertebral disc is still controversial. Several conservative modalities are available with varied results. Surgical discectomy may lead to failed back syndrome due to change in vertebral column anatomy and its mechanics. To prevent it, conservative means are better and Ozone discolysis is one of the nonsurgical methods. The indications and effectiveness of this condition is not well defined. The present study was done to correlate the clinical outcome of this technique.Methods: This was a prospective study conducted on 67 patients presenting with symptoms of back pain with arid without radicular symptoms. X ray and MRI were done in all cases. Then intradiscal ozone gas was given at one level from a specialized machine under C arm guidance. For evaluation Oswestry disability index and Macnab scoring system was used. Post injection patients were evaluated at 2, 6 weeks and 6 months.Results: Sixty seven patients with mean age of 47.7 years were followed up for 7.8 months. Low back pain was the commonest symptom and SLR was positive in 5.36%. The modified Macnab scoring with good and fair score improved from 16% to 89% and Oswestry disability index with minimal and moderate disability improved from 41% to 91% at end of 6 months. Seven patients had relapse of pain due to repeat disc prolapse. Conclusions: Ozone discloses is better modality of treatment for low back pain with disc bulge and early disc prolapsed.

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Efficacy of intradiscal ozone gas therapy combined with physical therapy in contained lumber disc prolapse

Bangladesh Medical Journal ◽

10.3329/bmj.v44i3.27374 ◽

2016 ◽

Vol 44 (3) ◽

pp. 146-151

Author(s):

Mohammad Moniruzzaman ◽

Md Shahadat Hosssain ◽

Md Ruhul Amin ◽

Moshiur Rahman Khasru ◽

Md Azizur Rahman ◽

...

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Physical Therapy ◽

Oswestry Disability Index ◽

Positive Outcome ◽

Outcome Variable ◽

Low Back ◽

Disc Prolapse ◽

Ozone Therapy ◽

College Hospital

Percutaneous intra-discal ozone therapy has promising results in contained lumber disc prolapse but the effectiveness of this treatment has been tested in large clinical studies show a positive outcome in 70%80% of patients. To increase success rate of ozone discectomy and prevention of disc surgery, intradiscal ozone therapy combined with physical therapy may bring new options for the management of low back pain (LBP) due to lumber disc prolpase. This prospective experimental study was done from August 2014 to Octber 2014 at the Popular Medical College Hospital, Dhanmondi, Dhaka, Bangladesh with the intention to assess the efficacy of percutaneous intra-discal ozone therapy combined with physical therapy in acute and chronic low back pain due to contained prolapsed intervertebral lumber disc (PLID). Seven (7) ml of oxygen-ozone mixture at a concentration of 30 mc/ml was injected in the disc by ozone resistant syringe over a period of 15-20 seconds. All patients got physiotherapy for 30 minutes, two times/day, up to two weeks and strictly maintained activities of daily living (ADL). The main outcome variable was VAS(Visual Analogue Scale) & ODI (Oswestry Disability Index). 100% patient experienced radiation of pain in the leg before ozone gas & physical therapy and 90% had relieved radiation till 4th week. The reduction of VAS score from baseline to four weeks following treatment was 8.0±1.63 to 0.30±0.95. Reduction of Oswestry Disability Index (ODI) from baseline to four weeks following treatment was 37.7±6.5 to 15.8±1.0. Percutaneous intra-discal ozone therapy in combination with physical therapy is an effective treatment for management of low back pain (LBP) due to contained lumber disc prolpase.Bangladesh Med J. 2015 Sep; 44 (3): 146-151

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Assessment of clinical efficacy of nefopam hydrochloride in lumbar disc prolapse patients in secondary care hospital

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20212513 ◽

2021 ◽

Vol 9 (7) ◽

pp. 1935

Author(s):

Suligeri Samarpana ◽

Yerukala Chamundeswari ◽

K. Jagadeesh ◽

C. Venkatesh ◽

G. Vinod ◽

...

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Drug Therapy ◽

Secondary Care ◽

Lumbar Disc ◽

Care Hospital ◽

Low Back ◽

Disc Prolapse ◽

Lumbar Disc Prolapse ◽

Pain Patients

Background: In this study assessing the efficacy of 30 mg of nefopam hydrochloride in lumbar disc prolapse patients.Methods: This was a prospective observational study. This study was carried out about 6 months in secondary care hospital. 100 patients are involved in this study. Patient documentation forms, visual analogue scale, patient counselling forms are the materials for this study. In this study patients visiting the Hospital with low back pain patients are included in the study. Pregnancy patients and failed back syndrome are excluded in the study. Results: In this study different age groups of patients as follows 21 patients in 20-30 years of age, 31 patients in 30-40 years of age, 37 patients in 40-60 years of age, 11 patients in 60-80 years of age.Percentage of pain relief of Nefopam hydrochloride drug therapy as follows, 23 patients in 10-20%, 16 patients in 20-40%, 38 patients in 40-60%, 16 patients in 60-80%, 7 patients in 80-100%. Assessing pain intensity in no. of patients after nefopam hydrochloride drug therapy are as follows 10patients has no pain, 28patients has mild pain, 34patients moderate pain, 15 patients has severe pain, 13 patients are worst pain.Conclusions: In current study demonstrated that the analgesic efficacies of nefopam hydrochloride in low back pain patients. Nefopam shows better action in mild, moderate, severe and worst pain. Nefopam shows high efficacy.

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Metrizamide Epidurography

Journal of the Royal Society of Medicine ◽

10.1177/014107688307600208 ◽

1983 ◽

Vol 76 (2) ◽

pp. 126-130 ◽

Cited By ~ 2

Author(s):

Gordon Hamilton

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Lumbar Disc ◽

Diagnostic Techniques ◽

Water Soluble ◽

Outpatient Basis ◽

Low Back ◽

Disc Prolapse ◽

Ionic Contrast ◽

Lumbar Disc Prolapse

The results are reported of lumbar epidurography in 110 patients suffering from low back pain. By using the water-soluble non-ionic contrast metrizamide, it has been possible to perform the examination on an outpatient basis. None of the patients has suffered from headache, nor any other complaint often associated with other diagnostic techniques which involve lumbar puncture. Epidurography is sufficiently accurate to be regarded as the examination of choice in the diagnosis of lumbar disc prolapse.

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Mechanism of Change Following Multidisciplinary Treatment of Low Back Pain Secondary to Lumbar Disc Prolapse

Journal of Evidence-Based Psychotherapies ◽

10.24193/jebp.2017.2.10 ◽

2017 ◽

Vol 17 (2) ◽

pp. 159-173

Author(s):

Ioana Onac ◽

◽

Daniel David ◽

Adela Moldovan ◽

Raluca Igna ◽

...

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Lumbar Disc ◽

Multidisciplinary Treatment ◽

Low Back ◽

Disc Prolapse ◽

Lumbar Disc Prolapse

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Correlation of Chronic Back Pain and Hyperuricemia, Our Hospital Experience

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i52b33628 ◽

2021 ◽

pp. 293-298

Author(s):

Atif Ahmed ◽

Muhammad Amjad Kalhoro ◽

Nasrullah Aamer ◽

Kuldeep Kumar ◽

Sant Das ◽

...

Keyword(s):

Uric Acid ◽

Low Back Pain ◽

Back Pain ◽

Chronic Low Back Pain ◽

Lumbar Disc ◽

Lumbosacral Spine ◽

Low Back ◽

Disc Prolapse ◽

Lumbar Disc Prolapse ◽

Significant Difference

Objective: This study aimed to analyze the prevalence of hyperuricemia in individuals with chronic low back pain. Methodology: It was a descriptive cross-sectional study performed between January 2021 to June 2021 in Medicine department of Bilawal Medical College LUMHS Jamshoro Pakistan. Patients between the age of 18 to 65 years have been investigated. Data was collected using a designed questionnaire. X-rays and Magnetic Resonance Imaging (MRI) of the lumbosacral spine were used to evaluate any discrepancies associated with low back pain. The levels of uric acid in the blood were measured and documented. Results: Out of 88 patients with chronic low back pain, 22 (25%) reported hyperuricemia. There was no significant difference in uric acid levels between men and women (P>0.05). We observed that 86.36 %t (n=19) patients with elevated serum uric acid levels also experienced joint pain. Further radiological examination revealed lumbar disc prolapse in 72.7 % (n=16). We found that in 95.45% of the patients, disc space narrowing was present. Conclusion: Regardless of gender, one in four people with low back pain had hyperuricemia. Patients with low back pain have varying occupational and co-morbidities. Hypouricemia appears to be associated with lumbar disc prolapse and lumbar vertebral joint space constriction. This reveals that hyperuricemia aggravates degenerative spondylolisthesis.

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ASSESSMENT OF THE EFFECTIVENESS OF HOMOEOPATHIC REMEDIES IN IMPROVING QUALITY OF LIFE OF CHRONIC LOW BACK PAIN: A PROSPECTIVE STUDY.

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v3i4.222 ◽

2019 ◽

Vol 3 (4) ◽

Author(s):

Dr Indrajeet P. Shah

Keyword(s):

Quality Of Life ◽

Low Back Pain ◽

Back Pain ◽

Chronic Low Back Pain ◽

Social Life ◽

Oswestry Disability Index ◽

Low Back ◽

Related Quality ◽

A Prospective Study

AIM & Objective: The main purpose of this study was to assess the results of Homoeopathic treatment in the management of chronic low back pain and to provide evidence of impact on the patients in terms of health status and health related quality of life. Methods: It was a single-centred, prospective, interventional study conducted at MNR UHC Homeopathic OPD in Sangareddy, from Dec 2018 to Feb 2019. At 0 day (Baseline) and 90 days standardized measuring scale were used like, Oswestry Disability Index, SF-12 questionnaire. Homoeopathic treatment was given to patients suffering from chronic low back pain. Results: Estimation of the Oswestry Disability Index showed that: severity of pain, personal care, sitting, standing, social life and travelling score were significantly improved (P<0.05).Significant differences were also found in the Quality of Life (QOL)‑SF 12 in physical domain [difference -19 (95% CI: -6.47, -0.43)], and psychological domain [difference -19 (95% CI: -6.31, -0.29](p ≤ 0.05). Conclusion: Homoeopathic treatment has made significant improvement in the patients suffering from chronic low back pain pertaining to the symptom’s severity. Further Randomised control trail can be conducted for validation of the results. Key words: Chronic Low Back pain, Homoeopathic, Oswestry disability.

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Injection of platelet rich plasma for low backpain caused by lumbar disc degeneration: a prospective study

International Journal of Research in Orthopaedics ◽

10.18203/issn.2455-4510.intjresorthop20203727 ◽

2020 ◽

Vol 6 (5) ◽

pp. 1032

Author(s):

M. Shanmugam ◽

Shivakumar .

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Disc Degeneration ◽

Platelet Rich Plasma ◽

Lumbar Disc ◽

Functional Improvement ◽

Low Back ◽

Lumbar Disc Degeneration ◽

Intradiscal Injection ◽

A Prospective Study

Background: Though the etiologies of chronic low back pain can be diverse, lumbar disc degeneration is one of the important causes of low backpain. In intractable cases of low back pain surgical interventions may be warranted. Intradiscal injection of platelet rich plasma is emerging as a novel treatment modality for chronic backpain and has been reported to have good results in terms of reduction of pain and improvement in functional abilities.Methods: This was a prospective study in which 30 patients with chronic low back pain were included. Platelet rich plasma was injected in nucleus pulposus of the affected part of lumbar spine under fluoroscopic control. Patients were followed up for 3 months. Reduction in severity of pain and functional improvement was assessed by Visual Analogue Scores (VAS) and Roland-Morris Low Back Pain and Disability Questionnaire (RDQ) scores.Results: The Mean age of the male patients was found to be 50.05±9.04 while the mean age of females was found to be 48.50±10.19. 18 (60%) patients were either overweight or obese. Remaining 12 (40%) patients had a normal BMI. The difference between mean VAS scores and RDQ scores at presentation and 3 months after PRP injection was found to be statistically highly significant (p<0.0001).Conclusions: The intradiscal injection of platelet rich plasma in patients with low back pain secondary to lumbar disc degeneration is effective in reducing back pain and causing significant functional improvement.

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