scholarly journals Conjunctival choristoma in an adolescent

2022 ◽  
Vol 7 (4) ◽  
pp. 736-738
Author(s):  
Mayank Gupta ◽  
Trupti Dubey ◽  
Rinaz Khan ◽  
Nitin Nema
Keyword(s):  
Histopathological Evidence

Conjunctival choristoma presents as a painless epibulbar mass comprising epidermal and dermal tissues. Histopathological evidence helps to establish the diagnosis. The tumor manifests in childhood, nonetheless, it may also be seen in adolescents.

Histopathological evidence of poor prognosis in patients with vesicoureteral reflux

2001 ◽  
Vol 16 (6) ◽  
pp. 482-487 ◽  
Author(s):  
Masaru Tada ◽  
Shiro Jimi ◽  
Satoshi Hisano ◽  
Yoshie Sasatomi ◽  
Kazuhiro Oshima ◽  
...  
Keyword(s):  
Vesicoureteral Reflux ◽  
Poor Prognosis ◽  
Histopathological Evidence

scholarly journals Histopathological Evidence for Irradiation Angiopathy in Head and Neck Cancer

2015 ◽  
Vol 04 (02) ◽  
pp. 108-114
Author(s):  
Nobuhiro Uwa ◽  
Hiroyuki Hao ◽  
Yoshitane Tsukamoto ◽  
Tomonori Terada ◽  
Kosuke Sagawa ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Histopathological Evidence

scholarly journals Increased proliferation is associated with CNS invasion in meningiomas

2021 ◽  
Author(s):  
Felix Behling ◽  
Christina Fodi ◽  
Sophie Wang ◽  
Johann-Martin Hempel ◽  
Elgin Hoffmann ◽  
...  
Keyword(s):  
Immunohistochemical Staining ◽  
Proliferative Activity ◽  
Who Classification ◽  
Prognostic Markers ◽  
Proliferative Potential ◽  
Prognostic Impact ◽  
Proliferation Marker ◽  
Automatic Quantification ◽  
Histopathological Evidence

Abstract Introduction Meningiomas are the most common benign intracranial neoplasms. CNS invasion in meningiomas has been integrated into the 2016 WHO classification of CNS tumors as a stand-alone criterion for atypia. Since then, its prognostic impact has been debated based on contradictory results from retrospective analyses. The aim of the study was to elucidate whether histopathological evidence of CNS invasion is associated with increased proliferative potential. Methods We have conducted a quantified measurement of the proliferation marker Ki67 and analyzed its association with CNS invasion determined by histology together with other established prognostic markers of progression. Routine, immunohistochemical staining for Ki67 were digitalized and automatic quantification was done using Image J software. Results Overall, 1718 meningiomas were assessed. Histopathological CNS invasion was seen in 108 cases (6.7%). Uni- and multivariate analysis revealed a significantly higher Ki67 proliferation rate in meningiomas with CNS invasion (p < 0.0001 and p = 0.0098, respectively). Conclusions Meningiomas with histopathological CNS invasion show a higher proliferative activity.

scholarly journals Solitary Schwannoma on the Hypothenar Region of the Hand: A Literature Review

2020 ◽  
Vol 5 (10) ◽  
pp. 449-452
Author(s):  
Kastanis G ◽  
Kapsetakis P ◽  
Magarakis G ◽  
Bachlitzanaki M ◽  
Christoforidis C ◽  
...  
Keyword(s):  
Literature Review ◽  
Clinical Diagnosis ◽  
Peripheral Nerves ◽  
Histopathological Examination ◽  
Final Diagnosis ◽  
Benign Tumors ◽  
Rare Manifestation ◽  
Histopathological Evidence ◽  
Volar Surface

Schwannomas or neurilemmomas are the most common benign tumors of the neural sheaths of the peripheral nerves. Incidence of these tumors in the hand accounts to 0.8-2%. The majority of them appear as an isolated grown mass along the route of the nerves. Peripheral nerves benign tumors present many difficulties concerning the clinical diagnosis and only histopathological evidence provides the final diagnosis. In this case study, we present a 45 year old man with a grown asymptomatic mass on the volar surface of right hand (hypothenar) remained for two years and impinging the skin of the hand only the last months. Initial MRI results diagnosed the mass as gaglion cyst. Histopathological examination revealed a schwannoma. We present this case as a rare manifestation of a schwannoma in hypothenar area of the hand. A literature review of diagnoses and therapeutic management is also presented.

scholarly journals Endobronchial tuberculosis: histopathological subsets and microbiological results

2012 ◽  
Vol 7 ◽  
Author(s):  
Sevket Ozkaya ◽  
Salih Bilgin ◽  
Serhat Findik ◽  
Hayriye Çete Kök ◽  
Canan Yuksel ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Lavage Fluid ◽  
Tracheobronchial Tree ◽  
Sputum Smear ◽  
Tuberculous Infection ◽  
Bronchial Lavage ◽  
Culture Positivity ◽  
Endobronchial Tuberculosis ◽  
Smear Negative ◽  
Histopathological Evidence

Background: Endobronchial tuberculosis (EBTB) is defined as a tuberculous infection of the tracheobronchial tree with microbial and histopathological evidence, with or without parenchymal involvement. Bronchoscopic appearances of EBTB have been divided into seven subtypes: actively caseating, edematous-hyperemic, fibrostenotic, tumorous, granular, ulcerative, and nonspecific bronchitic. However, information for establishing a definite microbiological diagnosis in each of these categories is lacking. We aimed to present bronchoscopic appearances and percentages for the EBTB subtypes and to compare bronchoscopic appearances with microbiological positivity in bronchial lavage fluid. Methods: From 2003 to 2009, 23 biopsy-proven EBTB patients were enrolled in the study. Diagnosis of EBTB was histopathologically confirmed in all patients. Results: The commonest subtype was the edematous-hyperemic type (34.7%); other subtypes in order of occurrence were: tumorous (21.7%), granular (17.3%), actively caseating (17.3%), fibrostenotic (4.3%), and nonspecific bronchitic (4.3%). Although all patients were sputum-smear-negative for acid-fast bacilli (AFB), 26% of patients were smear-positive for AFB in the bronchial lavage fluid. The bronchial lavage fluid grew Mycobacterium tuberculosis in 39.1% of all patients. The bronchial lavage smear positivity for AFB in the bronchial lavage fluid was 75%, 25%, 20%, 12.5%, 0%, and 0% for the granular, actively caseating, tumorous, edematous-hyperemic, fibrostenotic, and nonspecific bronchitic subtypes of EBTB, respectively. Culture positivity for Mycobacterium tuberculosis in bronchial lavage fluid was 75%, 50%, 40%, 25%, 0%, and 0%, respectively. Conclusion: The commonest subtype of EBTB was the edematous-hyperemic subtype. The granular type had the highest smear positivity and culture positivity for Mycobacterium tuberculosis in bronchial lavage fluid. Bronchoscopy should be performed in all patients suspected to have EBTB.

scholarly journals Nonpustular annular psoriasis: a variant of annular pustular psoriasis but without clinical or histopathological evidence of pustule formation

2016 ◽  
Vol 3 (6) ◽  
Author(s):  
Hidetoshi Takahashi ◽  
Katsuhiko Satoh ◽  
Akiyoshi Takagi ◽  
Akemi Ishida-Yamamoto ◽  
Hajime Iizuka
Keyword(s):  
Pustular Psoriasis ◽  
Histopathological Evidence

scholarly journals Treatment Strategies Based on Histological Targets against Invasive and Resistant Glioblastoma

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Akira Hara ◽  
Tomohiro Kanayama ◽  
Kei Noguchi ◽  
Ayumi Niwa ◽  
Masafumi Miyai ◽  
...  
Keyword(s):  
Glioma Cell ◽  
Treatment Strategies ◽  
Secondary Structures ◽  
Primary Brain Tumor ◽  
Therapeutic Interventions ◽  
High Recurrence Rate ◽  
Normal Brain ◽  
Biological Targets ◽  
Glioma Cell Migration ◽  
Histopathological Evidence

Glioblastoma (GBM) is the most common and the most malignant primary brain tumor and is characterized by rapid proliferation, invasion into surrounding normal brain tissues, and consequent aberrant vascularization. In these characteristics of GBM, invasive properties are responsible for its recurrence after various therapies. The histomorphological patterns of glioma cell invasion have often been referred to as the “secondary structures of Scherer.” The “secondary structures of Scherer” can be classified mainly into four histological types as (i) perineuronal satellitosis, (ii) perivascular satellitosis, (iii) subpial spread, and (iv) invasion along the white matter tracts. In order to develop therapeutic interventions to mitigate glioma cell migration, it is important to understand the biological mechanism underlying the formation of these secondary structures. The main focus of this review is to examine new molecular pathways based on the histopathological evidence of GBM invasion as major prognostic factors for the high recurrence rate for GBMs. The histopathology-based pharmacological and biological targets for treatment strategies may improve the management of invasive and resistant GBMs.

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