scholarly journals Evaluation of visual quality of spherical and aspherical intraocular lenses by Optical Quality Analysis System

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Zhonghao Ren ◽  
Liyan Xu ◽  
Qi Fan ◽  
Kaili Yang ◽  
Shengwei Ren ◽  
...  

Purpose. The study aimed to evaluate the visual quality of forme fruste keratoconus (FFK) and mild and moderate keratoconus by using an optical quality analysis system II (OQAS-II) and to explore the correlation between optical quality parameters and the disease progression. Methods. Twenty-one normal eyes, twenty-one FFK eyes, twenty-one mild keratoconus eyes, and twenty-one moderate keratoconus eyes were included in this prospective study. The optical quality parameters, such as object scatter index (OSI), modulation transfer function cutoff (MTF cutoff), strehl ratio (SR), and OQAS-II values at contrasts of 100% (OV-100), 20% (OV-20), and 9% (OV-9), were measured by OQAS-II. The repeatability of these parameters was analyzed by intraclass correlation coefficient (ICC), repeatability coefficient (RC), and coefficient of variation (CVw). Correlations between optical quality parameters and mean central keratometry readings (Kmean) were evaluated. The sensitivity and specificity of the parameters were analyzed using the receiver operating characteristic (ROC). Results. All the optical quality parameters among four groups showed good repeatability (all ICC≥0.75). The MTF cutoff, SR, OV-100, OV-20, OV-9 in FFK, mild and moderate keratoconus eyes were significantly lower than those in the normal group (all P<0.05). The ROC analyses of the MTF cutoff, SR, OV-100, OV-20, and OV-9 showed significant area under the curve (AUC) in discriminating FFK form normal, mild keratoconus from FFK, and moderate keratoconus from mild keratoconus (all P<0.05). The OSI in mild and moderate keratoconus eyes were significantly higher than that in FFK and normal group (all P<0.05), while the OSI showed no significant difference between the FFK group and normal group (P>0.05). The ROC analyses of the OSI showed significant AUC in discriminating mild keratoconus from FFK and moderate keratoconus from mild keratoconus (all P<0.05). In addition, the MTF cutoff was closely correlated to Kmean in keratoconus eyes (r = −0.710, P<0.001). Conclusion. The repeatability of OQAS-II is good in measuring visual quality of normal as well as FFK, mild, and moderate keratoconus. The visual quality of the FFK, mild, and moderate keratoconus is worse than that in normal eyes. The OQAS-II has the potential value in screening FFK from normal eyes and might be a useful tool for evaluating the progression of keratoconus.


2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Chang Won Park ◽  
Hyojin Kim ◽  
Choun-Ki Joo

Purpose. To assess visual function using Optical Quality Analysis System (OQAS) at varying levels of contrast in pseudophakic eyes.Methods. The study included patients admitted to Seoul St. Mary’s Hospital between January and February 2012: 143 pseudophakic eyes with one of five intraocular lens types, examined 2–6 months after cataract surgery, and 93 normal eyes (enhanced visual acuity (VA) < 0.1 logMAR) in age-matched controls. Subjects were examined at three contrast levels using the OQAS.Results. At 100%, 20%, and 9% contrast, simulated mean VA was0.16±0.18 logMAR,0.30±0.18 logMAR, and0.52±0.17 logMAR, in normal eyes, and0.16±0.12 logMAR,0.33±0.20 logMAR, and0.56±0.21 logMAR, respectively, in pseudophakic eyes. Simulated VA decreased significantly when contrast was reduced, regardless of ocular status, age group, and lens type (p<0.05). There were no significant differences between normal and pseudophakic eyes among subjects aged 50–69 (p>0.05). Among subjects aged 70–79, pseudophakic eyes showed improved simulated VA (p=0.000) and objective scattering index values (p=0.008).Conclusions. Patients with intraocular lenses have similar or superior visual function when compared to those with normal eyes at 2–6 months after cataract surgery, even under low-contrast conditions.


2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Yu-jing Wang ◽  
Yan-ning Yang ◽  
Lin-ying Huang ◽  
Bo Wang ◽  
Yu-can Han ◽  
...  

Background.To evaluate the optical quality and related factors in patients with ocular hypertension (OHT).Methods.This was a prospective case-control study. A total of 12 eyes with OHT and 20 control eyes underwent testing with Optical Quality Analysis System II (OQAS II) to evaluate the modulation transfer function cut off frequency (MTF cutoff), the Strehl 2D ratio (SR), objective scatter index (OSI), tear-film mean OSI (TFOSI), and the OQAS values (OV100%,OV20%, and OV9%).Results.The optical quality of patients with OHT declined, with lower MTF cutoff (OHT 36.86 ± 7.11 cpd , controls 48.50 ± 4.04 cpd,t=-4.60,P<0.05), lower SR (OHT 0.22 ± 0.04, controls 0.27 ± 0.05,t=-2.72,P<0.05), lower OV100% (OHT 1.26 ± 0.25, controls 1.61 ± 0.14,t=-4.03,P<0.05), lower OV20% (OHT 1.27 ± 0.27, controls 1.72 ± 0.20,t=-4.00,P<0.05), and lower OV9% (OHT 1.30 ± 0.25, controls 1.69 ± 0.32,t=-2.28,P<0.05). There were not any statistically significant differences in OSI and TFOSI. The MTF cutoff in patients with OHT was correlated significantly with age (r=-0.59,P<0.05).Conclusions.Optical quality of patients with OHT is reduced, with lower MTF cutoff, SR, OV100%, OV20%, and OV9%. MTF cutoff is negatively related to age.


2019 ◽  
Author(s):  
Yang Zhang ◽  
Ailing Bian ◽  
Qijun Hang ◽  
Qi Zhou

Abstract Purpose To investigate if optical quality assessed by Optical Quality Analysis System(OQAS)is a new factor for psychological disturbance and vision related quality of life(QoL) in Chinese patients with primary open angle glaucoma (POAG).Methods Cross-sectional study. OQAS, automated static perimetry, the Hospital Anxiety and Depression Scale (HADS) Questionnaire and the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) were used to assess optical quality, vision field, psychological health and QoL in 64 POAG patients. Correlation between the OQAS parameters and QoL or psychological health was analyzed by linear regression model.Results OQAS parameters, the modulation transfer function cut off frequency (MTF cutoff) and the mean OQAS values (mean OV), were significantly related to mean deviation (MD). Statistically significant correlation was also found between MTF cutoff, the mean OV and QoL in more than half of the NEI VFQ-25 subscale scores and the composite. The correlation coefficients between OQAS parameters and QoL were similar to those between MD and QoL in most of the subscale scores. HADS-Depression and HADS-Anxiety scores significantly correlated with MD in the worse eye, the composite and 3subscales of NEI VFQ-25, general health, social function and mental health, but uncorrelated with optical quality parameters measured by OQAS.Conclusions OQAS assessed optic quality is negatively related to MD and is a valid indicator for vision related QoL, but not for psychological health in our study group. OQAS might be an alternative or supplement to perimeter in POAG patients.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Bo Lu ◽  
Weijie Zhu ◽  
Yu Fan ◽  
Dong Shi ◽  
Liwei Ma

Abstract Background A prospective cohort study was performed to evaluate whether the Optical Quality Analysis System (OQAS) can serve as a valuable additional indicator for appropriate posterior capsulotomy referral. Methods One hundred and five eyes from 96 patients undergoing capsulotomy were divided into precapsulotomy logMAR CDVA ≤0.1 group and logMAR CDVA > 0.1 group. CDVA, and the Visual Function 14 index (VF-14) score were estimated before and 1 month after capsulotomy. The objective scattering index (OSI) value was measured by using the OQAS. Posterior capsule opacification (PCO) severity was assessed with Evaluation of PCO 2000 (EPCO 2000) software. Results In logMAR CDVA > 0.1 group, the correlations of OSI, logMAR CDVA, EPCO score and VF-14 score were very strong preoperatively. In logMAR CDVA ≤0.1 group, preoperatively, OSI was correlated with logMAR CDVA (r = 0.451), EPCO score (r = 0.789), and VF-14 score (r = 0.852). LogMAR CDVA has weak correlation with VF-14 score (r = − 0.384) and EPCO score (r = 0.566). VF-14 score was correlated with EPCO score (r = − 0.669). In the logMAR CDVA ≤0.1 group, there was no significant difference in logMAR CDVA between precapsulotomy and postcapsulotomy (P > 0.05). In the two groups, all the other optical quality parameters were significantly improved after capsulotomy (P < 0.05). In logMAR CDVA > 0.1 group, the area under the curve of the ROC of the OSI was 0.996 (P = 0.000). In logMAR CDVA ≤0.1 group, the area under the curve of the ROC of the OSI was 0.943 (P = 0.000). Conclusions The OSI was useful for evaluating of PCO and prediction of beneficial capsulotomy. Especially for patients with slight PCO and better visual acuity, OSI is more valuable than CDVA and completely objective examination. Trial registration The study protocol was registered at the Chinese Clinical Trial Registry. Register: ChiCTR1800018842 (Registered Date: October 13th, 2018).


2021 ◽  
pp. 112067212110021
Author(s):  
Javier Ruiz-Alcocer ◽  
Irene Martínez-Alberquilla ◽  
Amalia Lorente-Velázquez ◽  
José F Alfonso ◽  
David Madrid-Costa

Purpose: To objectively analyze the optical quality of the FineVision Toric intraocular lens (IOL) with two cylinder powers when different combinations of rotations and residual refractive errors are induced. Methods: This study assessed the FineVision Toric IOL with two different cylinder powers: 1.5 and 3.0 diopters (D). Three different rotation positions were considered: centered, 5° and 10° rotated. An optical bench (PMTF) was used for optical analysis. The optical quality of the IOLs was calculated by the modulation transfer function (MTF) at five different focal points (0.0, 0.25, 0.50, 0.75, and 1.00 D). Results: The MTF averaged value of the reference situation was 38.58 and 37.74 for 1.5 and 3.0 D of cylinder, respectively. For the 1.5 D cylinder, the combination of 5° of rotation with a defocus of 0.25, 0.50, 0.75, and 1.0 D induced a decrease on the MTF of 12.39, 19.94, 23.43, 24.23 units, respectively. When induced rotation was 10°, the MTF decrease was 17.26, 23.40, 24.33, 24.48 units, respectively. For the 3.0 D cylinder, the combination of 5° with 0.25, 0.50, 0.75, and 1.0 D of defocus, induced a decrease on the MTF of 12.51, 18.97, 22.36, 22.48 units, respectively. When induced rotation was 10°, the MTF decrease was: 18.42, 21.57, 23.08, and 23.61 units, respectively. Conclusion: For both FineVision Toric IOLs there is a certain optical tolerance to rotations up to 5° or residual refractive errors up to 0.25 D. Situations over these limits and their combination would affect the visual quality of patients implanted with these trifocal toric IOLs.


2017 ◽  
Vol 38 (3) ◽  
pp. 933-941
Author(s):  
Teresa Ferrer-Blasco ◽  
Alberto Domínguez-Vicent ◽  
Santiago García-Lázaro ◽  
María Amparo Diez ◽  
José F. Alfonso ◽  
...  

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