scholarly journals Applications of the isolated-check visual evoked potential in primary open angle glaucoma with or without high myopia

2021 ◽  
Vol 14 (5) ◽  
pp. 704-713
Author(s):  
Xia Wang ◽  
◽  
Ya-Hui Wei ◽  
Yuan Fang ◽  
Tian Tian ◽  
...  
Keyword(s):  
High Myopia ◽  
Diagnostic Performance ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Signal To Noise Ratio ◽  
Characteristic Curve ◽  
Open Angle ◽  
Visual Evoked

AIM: To explore the diagnostic performance of isolated-check visual evoked potential (icVEP) for primary open angle glaucoma (POAG) in both highly myopic and non-highly myopic populations and compare it with those of optical coherence tomography (OCT) and Heidelberg retinal tomography (HRT) parameters. METHODS: A total of 126 participants were recruited, including 31 highly myopic participants with POAG (HM-POAG), 36 non-highly myopic participants with POAG (NHM-POAG), 25 highly myopic participants without POAG (HM) and 34 controls without high myopia (Normal). All the participants underwent a complete ophthalmic examination. The signal-to-noise ratio (SNR) was used to assess the icVEP. Both qualitative and quantitative diagnostic performances of OCT, HRT and the icVEP were analyzed and compared. RESULTS: Based on the criterion of SNR≤1, the diagnostic performance of the icVEP in highly myopic subjects [area under the receiver operating characteristic curve (AUC)=0.862] was better than that in non-highly myopic subjects (AUC=0.789), and the SNR had fairly good specificity. In distinguishing the HM-POAG and HM groups, the AUC of the SNR was not different from those of the OCT and HRT parameters (P>0.05) in either the qualitative or quantitative comparison. In the qualitative analysis, the icVEP showed good consistency with damage to the central 10° of the visual field (kappa=0.695-0.747, P<0.001). CONCLUSION: The icVEP has the potential to discriminate individuals with and without POAG, especially in populations with high myopia.

Visual evoked potentials (VEP) studies in primary open glaucoma

2021 ◽  
Vol 19 (3) ◽  
pp. 28-31
Author(s):  
Bhagya V ◽  
Keyword(s):  
Optic Nerve ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Visual Pathway ◽  
Nerve Damage ◽  
Open Angle ◽  
Optic Nerve Damage ◽  
Visual Evoked

Background: With increasing prevalance of primary open angle glaucoma and optic nerve damage as a consequence of this, there is a need for early diagnosis and prevention of optic nerve damage. VEP, the potential recorded from the occipital region in response to the visual stimuli can be used for early detection of the primary open angle glaucoma. Visual evoked potential (VEP) is a non invasive method to assess the visual pathway. The present study was done to evaluate the impact of primary open angle glaucoma on central nervous system particularly, visual pathway. Methods: 30 primary open angle glaucoma patients attending outpatient department of ophthalmology department, SS hospital, Davanagere and 30 age matched controls selected randomly from general population were subjected to Visual evoked potential. Parameters for VEP such as latencies of waves N70, P100, and N155 peak-to-peak amplitudes of waves N70-P100 and P100-N155 were assessed and analyzed by using unpaired student-T test for comparison between cases and controls. Results: The present study observed that the there was a statistically significant increase in P100 latency in cases compared to the controls. And also there was a statistically significant decrease in N70 and P100 amplitude in cases compared to the controls. Conclusion: The present study correlates with earlier findings that visual pathway gets involved in primary open angle glaucoma even before the development of neuropathy which can be detected using VEP. Meticulous follow-up is a must to prevent the complications of primary open angle glaucoma, so that further damage can be prevented.

Accuracy of isolated-check visual evoked potential technique for diagnosing primary open-angle glaucoma

2017 ◽  
Vol 135 (2) ◽  
pp. 107-119 ◽  
Author(s):  
Li Juan Xu ◽  
Liang Zhang ◽  
Sha Ling Li ◽  
Vance Zemon ◽  
Gianni Virgili ◽  
...  
Keyword(s):  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Visual Evoked

scholarly journals Applications of Isolated-Check Visual Evoked Potential in Early Stage of Open-Angle Glaucoma Patients

2018 ◽  
Vol 131 (20) ◽  
pp. 2439-2446 ◽  
Author(s):  
Xiang Fan ◽  
Ling-Ling Wu ◽  
Xia Di ◽  
Tong Ding ◽  
Ai-Hua Ding
Keyword(s):  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Early Stage ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Visual Evoked

Clinical Profile of Myopic Patients as a Risk Factor for Primary Open Angle Glaucoma - A Prospective Observational Study in Gorakhpur, Uttar Pradesh

2021 ◽  
Vol 8 (33) ◽  
pp. 3084-3089
Author(s):  
Ram Kumar Jaiswal ◽  
Ramyash Singh Yadav ◽  
Mridula Ranjan ◽  
Dipti Wahi ◽  
Chiranji Rai
Keyword(s):  
Risk Factor ◽  
Intraocular Pressure ◽  
Observational Study ◽  
High Myopia ◽  
Central Corneal Thickness ◽  
Prospective Observational Study ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Corneal Thickness ◽  
Open Angle

BACKGROUND Myopia is a complex trait including both genetic and environmental factors as well as gene-environment interactions. It has been recognized as a risk factor for development of glaucoma. Both Myopia and raised IOP are known to increase mechanical stress at optic nerve head leading to glaucomatous nerve damage. This study intends to evaluate the clinical profile of myopic subjects and its correlation with Primary open angle glaucoma (POAG). METHODS A prospective observational study done from November 2019 to December 2020 after taking proper informed consent and ethical clearance. 164 eyes of 96 patients studied were divided into three groups, Group 1: low myopia (< -3.00D), Group 2: moderate myopia (-3.00 D to -5.75 D), Group 3: high myopia (≥ -6.00 D). A complete ocular examination was performed. Intraocular pressure was measured using Goldmann applanation tonometer. Visual field analysis using Humphrey automated perimetry was done in patients with suspected primary open angle glaucoma (POAG). Angle parameters and central corneal thickness (CCT) were measured using anterior segment optical coherence tomography (AS-OCT). RESULTS 164 eyes of 96 Myopic subjects were studied with no dropout during study period. Mean age was 46.05 yr. (range: 25-75 yr.). The refraction ranged from -0.50 DS to -17.00 DS. There was no statistically significant difference between Intraocular pressure (IOP), Central corneal thickness (CCT), corrected IOP and Nasal and Temporal Trabecular-iris Angle (TIA) between male and female of same age group. Mean IOP and mean CCT were found to vary significantly with age and with higher degree of myopia. Corrected IOP, Nasal and Temporal TIA increase significantly with higher degree of myopia. Cup-disc ratio (CDR) was found to be significantly higher in patients with moderate to high degree of Myopia. CONCLUSIONS Myopia is an important risk factor for development of primary open angle glaucoma, with its incidence increasing in patients with moderate to high myopia. KEYWORDS Myopia, Primary Open Angle Glaucoma, Intraocular Pressure, Central Corneal Thickness, Trabecular Iris Angle

Influence of high myopia on outcomes of trabeculectomy with mitomycin C in patients with primary open-angle glaucoma

2016 ◽  
Vol 60 (6) ◽  
pp. 446-453 ◽  
Author(s):  
Daisuke Tanaka ◽  
Hideo Nakanishi ◽  
Masanori Hangai ◽  
Tadamichi Akagi ◽  
Satoshi Morooka ◽  
...  
Keyword(s):  
Mitomycin C ◽  
High Myopia ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle
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