Wireless network led to the development of Wireless Sensor Networks (WSNs). A Wireless sensor network is a set of connected devices, sensors, and electronic components that can transmit the information collected from an observed field to the relevant node through wireless links. WSN has advanced many application fields. It can change any kind of technology that can modify the future lifestyle. WSNs are composed of tiny wireless computers that can sense the situation of atmosphere, process the sensor data, make a decision, and spread data to the environmental stimuli. Sensor-based technology has created several opportunities in the healthcare system, revolutionizing it in many aspects. This chapter explains in detail wireless sensor networks, their protocol, and performance metrics. The impact and role of the Biosensor in a wireless sensor network and healthcare systems are depicted. The integration of the computer engineering program into the WSNs is addressed.