scholarly journals Investigating the Role of Fluid Dynamics and Wall Mechanics in Atherosclerosis, Plaque Rupture, and Plaque Excavation in the Human Carotid Bifurcation

2021 ◽  
Author(s):  
Scott T. Lovald ◽  
Tariq Khraishi ◽  
Juan Heinrich ◽  
Howard Yonas ◽  
Christophe Taylor
Keyword(s):  
Fluid Dynamics ◽  
Plaque Rupture ◽  
Carotid Bifurcation ◽  
Human Carotid

Reproducibility of Image-Based Computational Fluid Dynamics Models of the Human Carotid Bifurcation

2003 ◽  
Vol 31 (2) ◽  
pp. 132-141 ◽  
Author(s):  
Jonathan B. Thomas ◽  
Jaques S. Milner ◽  
Brian K. Rutt ◽  
David A. Steinman
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Carotid Bifurcation ◽  
Dynamics Models ◽  
Human Carotid

Fusion of Histology and Shear Stress Based on In Vivo Images

2009 ◽  
Author(s):  
Harald C. Groen ◽  
Theo van Walsum ◽  
Frank J. H. Gijsen ◽  
Sietske Rozie ◽  
Stefan Klein ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Shear Stress ◽  
Plaque Rupture ◽  
Plaque Composition ◽  
Essential Step ◽  
Histological Processing ◽  
Plaque Destabilization ◽  
The Relationship

Evidence is accumulating for a role of high wall shear stress (WSS) in plaque destabilization, leading to plaque rupture [1–2]. To study this in detail we can use carotid plaques that are removed during surgery. The in vivo WSS distribution can be obtained by combining 3D lumen data, derived from pre-operative CT angiography (CTA) imaging, with computational fluid dynamics. Plaque composition can be studied by means of histological processing. Accurate registration of CT imaging with histology is an essential step to study the relationship between WSS and plaque composition.

Current Concepts in Cardiovascular Pathology: The Role of LDL Cholesterol in Plaque Rupture and Stabilization

1998 ◽  
Vol 104 (2) ◽  
pp. 14S-18S ◽  
Author(s):  
Peter Libby ◽  
Uwe Schoenbeck ◽  
Francois Mach ◽  
Andrew P Selwyn ◽  
Peter Ganz
Keyword(s):  
Ldl Cholesterol ◽  
Plaque Rupture ◽  
Cardiovascular Pathology

scholarly journals Glaucoma and the Role of Cerebrospinal Fluid Dynamics

2015 ◽  
Vol 56 (11) ◽  
pp. 6630 ◽  
Author(s):  
Peter Wostyn ◽  
Veva De Groot ◽  
Debby Van Dam ◽  
Kurt Audenaert ◽  
Hanspeter Esriel Killer ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Cerebrospinal Fluid ◽  
Cerebrospinal Fluid Dynamics
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