scholarly journals Central Odontogenic Fibroma Accompanied by a Central Giant Cell Granuloma-Like Lesion: Report of a Case and Review of Literature

2022 ◽  
Author(s):  
Monir Moradzadeh Khiavi ◽  
Abbas Karimi ◽  
Hassan Mirmohammad Sadeghi ◽  
Samira Derakhshan ◽  
Seyed Mobin Tafreshi ◽  
...  
Keyword(s):  
Giant Cell ◽  
Benign Lesion ◽  
Excisional Biopsy ◽  
Giant Cells ◽  
Histopathological Analysis ◽  
Giant Cell Granuloma ◽  
Multinucleated Giant Cells ◽  
Central Giant Cell Granuloma ◽  
Odontogenic Fibroma ◽  
Central Odontogenic Fibroma

Central giant cell granuloma (CGCG) is a benign non-neoplastic intraosseous lesion mainly found in the anterior mandible. It is characterized by multinucleated giant cells, representing osteoclasts or macrophages. Central odontogenic fibroma (COF) is an uncommon benign lesion of the jaws. It originates from the odontogenic ectomesenchyme. In rare cases, COF may accompany a CGCG. To date, 49 cases of COF accompanied by CGCG-like lesions have been reported in the literature. In this paper, we present another case of COF-CGCG in a 46-year-old female. The lesion was located in the posterior mandible. Excisional biopsy was carried out, and histopathological analysis revealed multinucleated giant cells with numerous strands of odontogenic epithelium. A literature review of previously reported cases was also performed.  

Hybrid central giant cell Granuloma and central Odontogenic Fibroma-Like Lesion of the Mandible

2008 ◽  
Vol 139 (6) ◽  
pp. 867-868 ◽  
Author(s):  
Lima Marina de Deus Moura de ◽  
Flávia Caló de Aquino Xavier ◽  
Luiz Augusto Vanti ◽  
Paulo Sérgio Fonseca Ribeiro de Lima ◽  
Suzana Cantanhede Orsini Machado de Sousa
Keyword(s):  
Giant Cell ◽  
Giant Cell Granuloma ◽  
Central Giant Cell Granuloma ◽  
Odontogenic Fibroma ◽  
Central Odontogenic Fibroma

scholarly journals A rare coexistence of central giant cell granuloma and parathyroid adenoma: Case report

2021 ◽  
Vol 6 (2) ◽  
pp. 155-158
Author(s):  
Rohini Sebastian ◽  
Meethu Rappai
Keyword(s):  
Case Report ◽  
Connective Tissue ◽  
Parathyroid Adenoma ◽  
Giant Cell ◽  
Stromal Cells ◽  
Giant Cells ◽  
Giant Cell Granuloma ◽  
Multinucleated Giant Cells ◽  
Central Giant Cell Granuloma ◽  
Bony Lesion

Central giant cell granuloma is a reparative bony lesion characterised by abundant multinucleated giant cells within a sea of spindle shaped mesenchymal stromal cells. Giant cells are scattered throughout the fibrovascular connective tissue stroma containing hemorrhage. Its coexistence with parathyroid adenoma is very rare. Brown tumour is a close differential in this scenario. Herein we present the case of a central giant cell granuloma of maxilla and parathyroid adenoma diagnosed almost during the same time in a 58 years old male.

Hybrid central giant cell granuloma and central odontogenic fibroma‐like lesions of the jaws

1997 ◽  
Vol 30 (2) ◽  
pp. 165-171 ◽  
Author(s):  
E.W. ODELL ◽  
T. LOMBARDI ◽  
A.W. BARRETT ◽  
P.R. MORGAN ◽  
P.M. SPEIGHT
Keyword(s):  
Giant Cell ◽  
Giant Cell Granuloma ◽  
Central Giant Cell Granuloma ◽  
Odontogenic Fibroma ◽  
Central Odontogenic Fibroma

Hybrid central giant cell Granuloma and central Odontogenic Fibroma-Like Lesion of the Mandible

2008 ◽  
Vol 139 (6) ◽  
pp. 867-868 ◽  
Author(s):  
Marina de Deus Moura de Lima ◽  
Flávia Caló de Aquino Xavier ◽  
Luiz Augusto Vanti ◽  
Paulo Sérgio Fonseca Ribeiro de Lima ◽  
Suzana Cantanhede Orsini Machado de Sousa
Keyword(s):  
Giant Cell ◽  
Giant Cell Granuloma ◽  
Central Giant Cell Granuloma ◽  
Odontogenic Fibroma ◽  
Central Odontogenic Fibroma

scholarly journals Case Report: rare hybrid lesion of a central giant cell granuloma within a juvenile ossifying fibroma

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 1218
Author(s):  
Hadeer Rizk Saad ◽  
Noura M. Kamal ◽  
Hatem W. Amer
Keyword(s):  
Connective Tissue ◽  
Giant Cell ◽  
Bone Lesion ◽  
Giant Cells ◽  
World Health ◽  
Ossifying Fibroma ◽  
Giant Cell Granuloma ◽  
Multinucleated Giant Cells ◽  
Central Giant Cell Granuloma ◽  
Juvenile Ossifying Fibroma

Central giant cell granuloma (CGCG) is classified by the World Health Organization as a benign bone lesion. It is found anteriorly in the mandible, with most of the cases crossing the midline. In total, 70% of CGCGs are encountered in young females. Fibro-osseous lesions are a group of pathologies that encompass neoplastic, dysplastic and reactive entities. Juvenile ossifying fibroma, which can be further categorized into juvenile trabecular ossifying fibroma (JTOF) and juvenile psammomatoid ossifying fibroma, represents an aggressive neoplastic example of these fibro-osseous lesions. JTOF occurs in children at almost equal ratios in both sexes, affecting the maxilla more than mandible. This study aims to report a peculiar case of a hybrid lesion comprising CGCG and JTOF in the mandible of a nine-year-old female patient. Clinical, radiographic and histopathological findings were assessed. Clinical examination revealed an intraoral swelling extending from the right impacted third molar area to the left first molar area. Computed tomography showed a well-defined multilocular radiolucency with diffuse flecks of radioopacities. Histopathologically, the lesion comprised fibrous connective tissue encompassing numerous multinucleated giant cells and other areas of cell-rich connective tissue stroma containing bands of osteoid matrix and anastomosing immature bone trabeculae intermixed with scattered clusters of multinucleated giant cells. We hereby report a case of a rare hybrid lesion comprising CGCG and JTOF.

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