scholarly journals Comparing Neurocognitive Profile of Patients with Borderline Personality and Bipolar–II Disorders

Author(s):  
Valiolah Akbari ◽  
Parvin Rahmatinejad ◽  
Seyed Davood Mohammadi

Objective: The present study was conducted to compare neurocognitive profile in patients with borderline personality disorder (BPD) and bipolar II disorder (BD-II) and to find whether BPD can be classified as one of bipolar spectrum disorders. Method: A total of 35 patients with BPD and 35 euthymic patients with BDII disorder were selected by convenience sampling method. These 2 groups were compared with 30 healthy individuals using neurocognitive battery tests that assessed cognitive flexibility and set-shifting, response inhibition, problem-solving, decision-making, and sustained and selective attention. Data were analyzed using independent t test, X2 and ANOVA. Results: Patients with euthymic BDII and BPD had poorer performance than the healthy group in most neurocognitive domains (p<0.05). Both patient groups showed similar functions in cognitive flexibility and set-shifting, decision-making, sustained and selective attention, and problem-solving (p<0.05). BPD patients had more elevated response inhibition deficits than BD-II patients (P<0.05). Also, BPD patients had poorer performance in planning compared to BD-II patients (P<0.05). Conclusion: The results provided empirical support for previous findings which have reported that patients with BPD and BD-II show neurocognitive dysfunctions. Despite the similarity between these 2 clinical groups in terms of neurocognitive profile in this study, more extensive studies are needed to confirm the hypothesis that BPD can be conceptualized as one of bipolar spectrum disorders.

2012 ◽  
Vol 14 (2) ◽  
pp. 91-109
Author(s):  
Jill Littrell

The diagnosis of bipolar spectrum disorders (BSD) given for office visits has risen 40-fold for children and has risen dramatically for adults as well. Some of the growth may have been fueled by recategorization of individuals who would previously have received diagnoses of major depression along with the widening of diagnostic criteria for BSD. Concomitant with the rise in BSD diagnoses, the number of adults and children receiving atypical antipsychotics has increased dramatically. Recent evidence finds that atypical antipsychotics cause considerable reduction in brain volume. It is thus imperative to ensure that those with diagnoses comprising BSD—bipolar I, bipolar II, and bipolar not otherwise specified (BP-NOS)—actually share a common etiology and are being appropriately treated. This article reviews the history, evidentiary support, and implications associated with the expansion of the bipolar spectrum.


Author(s):  
Viktoriya Fedchenko

The materials of the article are devoted to the study of the possibilities of early detection of bipolar affective disorder (BAD) type II using a screening questionnaire in patients diagnosed with dysthymia. The reasons of late diagnosis of bipolar spectrum disorders, difficulties in detecting episodes of hypomania, consequences of incorrect diagnosis, screening systems for early detection of BAD are considered. The effectiveness of using The Bipolar Spectrum Diagnostic Scale (BSDS) to establish the possibility of BAD in patients with dysthymia has been substantiated. Indicators obtained by the BSDS scale show that 27.78 % of patients with dysthymia have a moderate probability of bipolar spectrum disorders, 16.67 % of patients in this category — low probability and 8.33 % of subjects — high probability. It was found that a high and moderate probability of bipolar spectrum disorders is associated with the early onset of dysthymia (r = 0.421 and r = 0.396, respectively).


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