scholarly journals Water-drinking Test and Pharmacologic Mydriasis as Provocative Tests in Primary Angle Closure Suspects

2019 ◽  
Author(s):  
Reza Razeghinejad ◽  
M. Hossein Nowroozzadeh
Keyword(s):  
Angle Closure ◽  
Laser Peripheral Iridotomy ◽  
Provocative Test ◽  
Water Drinking ◽  
Primary Angle Closure ◽  
Post Test ◽  
Drinking Test ◽  
The Mean ◽  
Iop Elevation ◽  
Water Drinking Test

Purpose: To compare the water-drinking test (WDT) and pharmacologic mydriasis as provocative tests in patients with primary angle closure suspect (PACS). Methods: This observational non-randomized comparative study evaluated changes in intraocular pressure (IOP) in 21 patients with PACS who underwent pharmacologic mydriasis and compared it with IOP changes in 26 patients given the WDT. Ocular biometric and anterior chamber parameters were also assessed. Tests were repeated on the same patient two weeks after performing laser peripheral iridotomy (LPI). Results: The mean age ± standard deviation was 60 ± 7 and 57 ± 9 years in the mydriasis and WDT groups, respectively (P = 0.201). Before LPI, both provocative tests were associated with a significant increase in IOP (mydriasis: 15.1 ± 3.1 to 16.6 ± 3.5 mmHg, P = 0.025; WDT: 16.2 ± 2.8 to 18.5 ± 3.3 mmHg, P < 0.001). However, the IOP changes were not statistically different between groups (P = 0.102). After LPI, only the WDT group showed a continued significant IOP elevation after the test (mydriasis: 16.4 ± 3.3 to 16.7 ± 3.5 mmHg, P = 0.569; WDT: 14.9 ± 3.0 to 17.8 ± 4.1 mmHg, P < 0.001). The post-test IOP change was significantly greater in the WDT than in the mydriasis group (3.0 versus 0.3 mmHg, respectively; P = 0.002). Step-wise multiple regression analysis verified the type of provocative test as the only independent factor affecting the post-test IOP change after LPI (regression coefficient: 2.664; P = 0.002). Conclusion: Pharmacologic mydriasis and the WDT had similar IOP elevation before LPI, but after LPI, IOP elevation was much greater in the WDT group.

scholarly journals Water-drinking test in primary angle-closure suspect before and after laser peripheral iridotomy

2015 ◽  
Vol 44 (2) ◽  
pp. 89-94 ◽  
Author(s):  
Michael Waisbourd ◽  
Shravan V Savant ◽  
Yi Sun ◽  
Patricia Martinez ◽  
Jonathan S Myers
Keyword(s):  
Angle Closure ◽  
Laser Peripheral Iridotomy ◽  
Water Drinking ◽  
Primary Angle Closure ◽  
Before And After ◽  
Drinking Test ◽  
Peripheral Iridotomy ◽  
Water Drinking Test

Results for Water-drinking Test, before and after Laser Iridotomy, in Primary Angle-closure Suspects

2018 ◽  
Vol 95 (2) ◽  
pp. 150-154 ◽  
Author(s):  
M. Reza Razeghinejad ◽  
Parisa Karampour ◽  
Masoumeh Beigom Masoumpour ◽  
Zahra Tajbakhsh ◽  
M. Hossein Nowroozzadeh
Keyword(s):  
Angle Closure ◽  
Laser Iridotomy ◽  
Water Drinking ◽  
Primary Angle Closure ◽  
Before And After ◽  
Drinking Test ◽  
Water Drinking Test

Evaluation of daily changes of Intraocular pressure in glaucomatous patients with modified diurnal tension curve versus water drinking test

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Eman Sayed Ahmed ◽  
Mohammed Adel Abdelshafik ◽  
Momen Mahmoud Hamdi ◽  
Noha Mohsen Mahmoud
Keyword(s):  
Intraocular Pressure ◽  
Open Angle Glaucoma ◽  
Control Group ◽  
Case Group ◽  
Provocative Test ◽  
Water Drinking ◽  
Drinking Test ◽  
The Mean ◽  
Tension Curve ◽  
Water Drinking Test

Abstract Background Glaucoma is a chronic optic neuropathy characterized by the excavation of the optic disc due to atrophy of the retinal ganglion cells. A progression of such atrophy leads to reduction of the visual field and eventually to the loss of sight at the end-stage of the disease, Glaucoma is the second leading cause of blindness worldwide Objectives To study the correlation between intraocular pressure (IOP) fluctuation during water drinking test (WDT) and the IOP fluctuation of modified diurnal tension curve (mDTC) in glaucomatous eyes Patients and Methods Fifty participants (24 males and 26 females) were recruited in this prospective study; forty participants with known Primary Open Angle Glaucoma and the other ten participants with non- glaucomatous healthy eyes which served as control. Patients attending the outpatient clinic at Al-Demerdash Hospital and Cairo Fatemic Hospital from October 2018 to March 2019 were prospectively recruited. Four IOP measurements were taken at 8:00 am, 12:00 pm, 4:00 pm and 8:00 pm which represented the mDTC, while WDT was represented by a single measurement of IOP before ingestion of one liter of water over five minutes, followed by three IOP measurements after ingestion of this amount of water at thirty minute intervals. Results Distribution of the studied participants as regards Age and sex: 50 participants were included in the this study. 40 presented the case group (20 males and 20 females) and the mean age of the case group was 54.7 years, 10 presented the control group(4 males and 6 females) and the mean age of the control group was 51.2years. 59% of participants had a peak IOP at 8:00 am, while 10% had a peak IOP at 12:00 pm, 6% at 4:00 pm and 25% of the participants had IOP peak at 8:00 pm during the mDTC. In the WDT, 96% of the participants had a peak IOP after 30 minutes of ingesting one liter of water, while 4% had a peak IOP after 60 minutes. None of the participants had IOP peak after 90 minutes of ingesting one liter of water.. The IOP fluctuations detected during the WDT were significantly correlated to fluctuations observed during the mDTC. Conclusion The data of this study suggested that WDT can be used as a useful provocative test for the detection of the diurnal IOP peaks and fluctuation observed in the glaucoma patients.

Comparison between provocative test-based and long-term intraocular pressure parameters in patients with stable open-angle glaucoma

2020 ◽  
pp. 112067212091133
Author(s):  
Izabela Almeida ◽  
Ana Luiza B Scoralick ◽  
Diego T Dias ◽  
Michele Ushida ◽  
Syril Dorairaj ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Provocative Test ◽  
Water Drinking ◽  
Medical Regimen ◽  
Pressure Peak ◽  
Drinking Test ◽  
Water Drinking Test

Purpose: To compare provocative test-based and long-term intraocular pressure variation parameters in patients with stable open-angle glaucoma. Methods: A prospective observational study was carried out in which stable open-angle glaucoma patients (⩾3 years of follow-up without any changes on current medical regimen) were consecutively enrolled. All patients were submitted to a water-drinking test. Long-term intraocular pressure parameters were obtained from isolated intraocular pressure measurements from each visit (⩾5 visits). We investigated the correlation and agreement between the following water-drinking test and long-term intraocular pressure parameters: mean, peak, and fluctuation. In addition, the percentage of eyes with significant intraocular pressure peaks during the water-drinking test (defined as a difference ⩾25% between water-drinking test intraocular pressure peak and mean long-term intraocular pressure) was assessed. Results: Sixty-three eyes from 63 open-angle glaucoma patients (mean age, 60.7 ± 11.8 years) were included. Mean and water-drinking test intraocular pressure peak correlated significantly with mean ( r = 0.67) and maximum long-term intraocular pressure ( r = 0.52), respectively ( p < 0.01). The correlation between water-drinking test intraocular pressure fluctuation and long-term intraocular pressure fluctuation was not significant ( p = 0.45). Limits of agreement from Bland–Altman plots exceeded the maximum allowed difference between methods (3 mm Hg) for all the intraocular pressure parameters analyzed, suggesting poor agreement between water-drinking test–derived and long-term intraocular pressure values. Overall, significant water-drinking test intraocular pressure peaks were observed in 39.7% of these eyes with stable open-angle glaucoma. Conclusion: Although some water-drinking test–based and long-term intraocular pressure parameters correlate significantly, water-drinking test results may not reflect the long-term intraocular pressure profile of stable open-angle glaucoma patients, as their agreement is poor. Many of these patients may experience significant water-drinking test intraocular pressure peaks, despite long-standing stable disease and unchanged medical regimen.

scholarly journals Intraocular Pressure Changes after Water Drinking Test in Surgically Treated Primary Congenital Glaucoma

2020 ◽  
Author(s):  
Reza Razeghinejad ◽  
Zahra Tajbakhsh ◽  
Masoumeh Beigom Masoumpour ◽  
M. Hossein Nowroozzadeh
Keyword(s):  
Intraocular Pressure ◽  
Repeated Measures ◽  
Congenital Glaucoma ◽  
Glaucoma Drainage Device ◽  
Primary Congenital Glaucoma ◽  
Water Drinking ◽  
Drinking Test ◽  
The Mean ◽  
The Difference ◽  
Water Drinking Test

Purpose: To assess intraocular pressure (IOP) changes after the water drinking test (WDT) in patients with primary congenital glaucoma (PCG). Methods: In this prospective interventional study, 20 eyes of 20 patients with PCG were included. All patients had undergone trabeculotomy. Six out of twenty eyes had received a glaucoma drainage device (GDD) implantation. IOP was measured using an air-puff tonometer at baseline, and 15, 30, 45, and 60 min after WDT. The repeated-measures analysis of variance test was used to compare the mean IOPs at different time points. Results: The mean (± standard deviation) of participants’ age was 9.9 ± 2.7 years (range, 6 to 16 years), and 8 (40%) participants were male. The mean IOPs at baseline and 15, 30, 45, and 60 minutes after the WDT were 15.8 ± 3.7, 18.6 ± 3.4, 19.0 ± 3.8, 17.9 ± 3.8, and 16.9 ± 3.5 mmHg, respectively (P < 0.001). Pairwise comparisons revealed that the mean IOPs after 15 and 30 min were significantly greater than the baseline IOP (P < 0.001 and P = 0.002, respectively); however, the difference in mean IOPs after 45 and 60 min were not statistically significant from the baseline IOP. The averages of IOP peak and IOP fluctuation after the WDT were 20.0 ± 3.5 and 4.2 ± 2.9 mmHg, respectively. IOP fluctuation in those who underwent trabeculotomy alone was twice that of those with GDDs, but the difference was not statistically significant (5.0 vs 2.5 mmHg; P = 0.08). Conclusions: In patients with PCG, WDT induced significant IOP elevation 15 and 30 min after the test, which returned to pre-test values after 45 min.

scholarly journals Comparison of intraocular pressure peak and fluctuations among Filipino patients with non-glaucomatous eyes and glaucoma suspects using water drinking test and diurnal intraocular pressure

2021 ◽  
Vol 14 (11) ◽  
pp. 1729-1734
Author(s):  
Anelisa Koh ◽  
Keyword(s):  
Intraocular Pressure ◽  
Diagnostic Tests ◽  
Normal Group ◽  
Glaucoma Suspect ◽  
Water Drinking ◽  
Pressure Peak ◽  
Drinking Test ◽  
The Mean ◽  
Diurnal Iop ◽  
Water Drinking Test

AIM: To compare the intraocular pressure (IOP) peaks and fluctuations using water drinking tests (WDTs) and mean diurnal IOP among Filipino patients with normal eyes and glaucoma suspects METHODS: This prospective study included normal and glaucoma suspect patients. Each patient underwent both WDT and mean diurnal examination on separate visits. For mean diurnal examination, IOP was recorded every 2h for 8h while in WDT, IOP was recorded prior to WDT, and post-WDT at 5, 15, 30, 45, and 60min. IOP peak was recorded as the highest IOP for both methods, and IOP fluctuation was recorded as highest IOP minus lowest IOP. RESULTS: With the comparison of diagnostic tests, both normal eyes and glaucoma suspect groups, the peak IOP was caught at 15min. Comparative analysis of both groups also showed that the peak IOP measurements were statistically higher for the WDT compared to mean diurnal IOP (P=0.039, P=0.048 under normal group and P=0.032 and P=0.031 under glaucoma suspect group). Similarly, the WDT had a statistically higher mean IOP fluctuation score than the mean diurnal IOP method in both groups (P=0.003, P=0.011 under normal group; P=0.002 and P=0.005 under glaucoma suspect group). CONCLUSION: This study shows that WDT is a comparable diagnostic exam in predicting IOP fluctuations than mean diurnal measurement. WDT is a promising diagnostic procedure for risk assessment in glaucoma.

scholarly journals Water-drinking Test in Normal Tension Glaucoma Patients with and without High Myopia

2021 ◽  
Author(s):  
Alexander Chen ◽  
Ming-Tse Kuo ◽  
Pei-Wen Lin
Keyword(s):  
High Myopia ◽  
Normal Tension Glaucoma ◽  
Fiber Layer ◽  
Water Drinking ◽  
Nerve Fiber Layer Thickness ◽  
Drinking Test ◽  
Iop Elevation ◽  
Minute Duration ◽  
Basic Characteristics ◽  
Water Drinking Test

Abstract This prospective study aims to evaluate the correlation between myopic severity and normal tension glaucoma (NTG) by investigating IOP changes following water-drinking test (WDT). We reviewed 61 patients with NTG during an interval of three years, of which 31 were highly myopic (HM) and 30 were non-highly myopic (NHM). Basic characteristics such as age, gender, spherical equivalence, baseline IOP, visual field parameters, and average retinal nerve fiber layer thickness were compared between NTG patients with and without high myopia. The IOP parameters obtained following WDT were then compared between the HM and NHM NTG groups. Intragroup analysis revealed significant IOP elevation following WDT within the 45-minute duration in both groups. However, no significant differences in IOP parameters were observed between the HM and NHM NTG groups. In conclusion, although the pattern of IOP fluctuations was different, the extent of IOP fluctuations and peak IOP following WDT was similar between the HM and NHM NTG groups, suggesting that myopic severity probably has a limited role in NTG. Lastly, WDT was an effective tool for eliciting IOP peaks when 24-hour IOP monitoring is not available.

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