scholarly journals Water-drinking Test in Normal Tension Glaucoma Patients with and without High Myopia

Author(s):  
Alexander Chen ◽  
Ming-Tse Kuo ◽  
Pei-Wen Lin

Abstract This prospective study aims to evaluate the correlation between myopic severity and normal tension glaucoma (NTG) by investigating IOP changes following water-drinking test (WDT). We reviewed 61 patients with NTG during an interval of three years, of which 31 were highly myopic (HM) and 30 were non-highly myopic (NHM). Basic characteristics such as age, gender, spherical equivalence, baseline IOP, visual field parameters, and average retinal nerve fiber layer thickness were compared between NTG patients with and without high myopia. The IOP parameters obtained following WDT were then compared between the HM and NHM NTG groups. Intragroup analysis revealed significant IOP elevation following WDT within the 45-minute duration in both groups. However, no significant differences in IOP parameters were observed between the HM and NHM NTG groups. In conclusion, although the pattern of IOP fluctuations was different, the extent of IOP fluctuations and peak IOP following WDT was similar between the HM and NHM NTG groups, suggesting that myopic severity probably has a limited role in NTG. Lastly, WDT was an effective tool for eliciting IOP peaks when 24-hour IOP monitoring is not available.

Author(s):  
Reza Razeghinejad ◽  
M. Hossein Nowroozzadeh

Purpose: To compare the water-drinking test (WDT) and pharmacologic mydriasis as provocative tests in patients with primary angle closure suspect (PACS). Methods: This observational non-randomized comparative study evaluated changes in intraocular pressure (IOP) in 21 patients with PACS who underwent pharmacologic mydriasis and compared it with IOP changes in 26 patients given the WDT. Ocular biometric and anterior chamber parameters were also assessed. Tests were repeated on the same patient two weeks after performing laser peripheral iridotomy (LPI). Results: The mean age ± standard deviation was 60 ± 7 and 57 ± 9 years in the mydriasis and WDT groups, respectively (P = 0.201). Before LPI, both provocative tests were associated with a significant increase in IOP (mydriasis: 15.1 ± 3.1 to 16.6 ± 3.5 mmHg, P = 0.025; WDT: 16.2 ± 2.8 to 18.5 ± 3.3 mmHg, P < 0.001). However, the IOP changes were not statistically different between groups (P = 0.102). After LPI, only the WDT group showed a continued significant IOP elevation after the test (mydriasis: 16.4 ± 3.3 to 16.7 ± 3.5 mmHg, P = 0.569; WDT: 14.9 ± 3.0 to 17.8 ± 4.1 mmHg, P < 0.001). The post-test IOP change was significantly greater in the WDT than in the mydriasis group (3.0 versus 0.3 mmHg, respectively; P = 0.002). Step-wise multiple regression analysis verified the type of provocative test as the only independent factor affecting the post-test IOP change after LPI (regression coefficient: 2.664; P = 0.002). Conclusion: Pharmacologic mydriasis and the WDT had similar IOP elevation before LPI, but after LPI, IOP elevation was much greater in the WDT group.


Clinics ◽  
2010 ◽  
Vol 65 (10) ◽  
pp. 967-970 ◽  
Author(s):  
Rafael Lacerda Furlanetto ◽  
Antonio Carlos Facio Jr ◽  
Marcelo Hatanaka ◽  
Remo Susanna Junior

2017 ◽  
Vol 1 (3) ◽  
pp. 47-59
Author(s):  
Fauze A. Goncalves ◽  
Fernando Henrique R. Amorim ◽  
Camila S. Zangalli ◽  
Jose Paulo C. Vasconcellos ◽  
Vital P. Costa

Aim: To investigate whether the water-drinking test (WDT) and the postural-change test (PCT) can predict the 24-hour diurnal tensional curve (DTC) intraocular pressure (IOP) peak and fluctuation by assessing the correlation and agreement between these three tests in medically treated primary open-angle glaucoma (POAG) patients.Methods: 18 POAG patients underwent the DTC, WDT and PCT. Pearson’s correlation coefficient and Bland-Altman plots were used to assess the correlation and agreement between the results, respectively.Results: Mean DTC IOP peak was 18.72 + 4.31 mmHg and mean DTC IOP fluctuation was 7.00 + 2.54 mmHg. The IOP peak was outside office hours in 50% of the subjects. We observed poor correlations between the DTC and WDT fluctuations and the DTC and PCT fluctuations (r=-0.125, P=0.619; r=0.349, P=0.155, respectively). There was a moderate positive correlation between the DTC and WDT peaks (r=0.493, P=0.03) and a strong positive correlation between the DTC and PCT peaks (r=0.722, P<0.001). However, Bland-Altman plots demonstrated poor agreement between the IOP peaks and fluctuations between the 3 tests. WDT and DTC IOP peaks differed by 2 mmHg or more in 56% of the measurements. PCT and DTC IOP peaks showed that 83% of the measurements had differences greater than 2 mmHg.Conclusions: Despite moderate to strong correlations between DCT and WDT peaks and DTC and PCT IOP peaks, the agreement was generally poor, suggesting that they should be used with caution to estimate peak IOP.


Ophthalmology ◽  
2019 ◽  
Vol 126 (4) ◽  
pp. 522-528 ◽  
Author(s):  
Min-Woo Lee ◽  
Ju-mi Kim ◽  
Yong-Il Shin ◽  
Young-Joon Jo ◽  
Jung-Yeul Kim

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