An 8-year retrospective review of gastrointestinal medical emergency conditions at a tertiary health facility in Nigeria

Background: Globally, gastrointestinal emergency conditions constitute a considerable proportion of the medical emergency cases seen in the emergency room.Objective: This study investigated the spectrum of gastrointestinal medical emergency conditions seen in the emergency room of Federal Teaching Hospital Ido-Ekiti, Nigeria.Materials and Methods: The emergency room admission register was used to obtain the following information: Age, Sex, Diagnosis, Year of admission and the Outcome. The period under review was 1st January 2009 to 31st December 2016. The data was analyzed using the SPSS version 21.0 software package.Results: A total number of 5,912 patients with medical emergency conditions were admitted into the emergency room during the period under review, out of which 813(13.7%) were gastrointestinal medical emergency conditions. The age range of the patients was 15 to 100years with a mean(±SD) of 47.32±18.938. Acute exacerbation of acid peptic disorders(29.3%) was the most common indication for emergency room admission followed by acute gastroenteritis(26.8%) and decompensated chronic liver disease(14.3%). Decompensated chronic liver disease and upper gastrointestinal bleeding were the conditions with the highest mortality being 31.8% and 29.5% respectively.Conclusion: Gastrointestinal medical conditions are common indications for emergency admission. Measures should be taken to avoid these preventable conditions in a bid to reduce their morbidity and mortality.

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Prevalence and Short Term Outcome of Spontaneous Bacterial Peritonitis of Known Chronic Liver Disease Patients

Medicine Today ◽

10.3329/medtoday.v27i1.25992 ◽

2015 ◽

Vol 27 (1) ◽

pp. 15-19 ◽

Cited By ~ 1

Author(s):

Mohammad Ismail ◽

Mohammad Anisur Rahman

Keyword(s):

Liver Disease ◽

Chronic Liver Disease ◽

Ascitic Fluid ◽

Spontaneous Bacterial Peritonitis ◽

Chronic Liver ◽

Medical Emergency ◽

P Value ◽

Prospective Longitudinal Study ◽

Bacterial Peritonitis ◽

Prospective Longitudinal

Spontaneous bacterial peritonitis (SBP) is an infection of ascitic fluid occurring in the absence of a contiguous source of infection characterized by symptoms of fever, abdominal pain, rebound tenderness, encephalopathy. It may develope in hospitalized patients and mortality rate is significantly high. To determine the prevalence of SBP in chronic liver disease with ascites and to establish that SBP is the cause of higher mortality than non SBP, a prospective longitudinal study was carried out in patients attending in the inpatient Department of Gastroenterology of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorder Hospital(BIRDEM), Bangabandhu Sheikh Mujib Medical University(BSMMU), Dhaka Medical College Hospital(DMCH), Dhaka from March 2010 to September 2010. Among the 60 patients the most common age group was the 46-55 years. In physical finding below average body build was found in 48 (80.0%) cases. Malnutrition was found in 48(80.0%) cases. Per abdominal finding liver was not palpable in 54 (90.0%) cases. Shifting dullness was found in 59 (98.3%) cases. Fluid thrill was detected in 57 (95.0%) cases. It was found that SBP were developed in 11(18.3%) cases and remaining 49(81.7%) case were non SBP, which were higher than SBP. Organism of culture of ascitic fluid in SBP patients (n=11) were E. coli and Pseudomoas spp found in 2(18.2%) cases, the rest 6(54.5%) cases shows no growth. Among 11 SBP patients improvement occurred in 5(45.5%) cases and the rest 6(54.5%) cases died p value <.001. SBP is medical emergency, prompt management and prophylactic antibiotics are essential to reduce mortality.Medicine Today 2015 Vol.27(1): 15-19

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Role of Rifaximin in Prevention of Recurrent Hepatic Encephalopathy in Chronic Liver Disease

Journal of Bahria University Medical and Dental College ◽

10.51985/jbumdc2020030 ◽

2020 ◽

Vol 10 (4) ◽

pp. 257-260

Author(s):

Sahar Farzand ◽

Abdul Khattak ◽

Rafi ud Din ◽

Karamat Bukhari ◽

Muhammad Amin ◽

...

Keyword(s):

Liver Disease ◽

Hepatic Encephalopathy ◽

Chronic Liver Disease ◽

Chronic Liver ◽

Military Hospital ◽

P Value ◽

Female Ratio ◽

Duration Of Disease ◽

Disease Study ◽

Age Range

Objectives: To determine the efficacy (in terms of recurrence) of rifaximin in Hepatic Encephalopathy (HE) in chronic liver disease. Study Design and Setting: A descriptive study carried out from 4th September 2018 to 3rd March 2019 at the department of Medicine, Combined Military Hospital, Quetta. Methodology: A total of 104 patients of chronic liver disease with HE, 25-65 years and both genders were included. Patients with gastrointestinal hemorrhage, chronic renal insufficiency and anemia were excluded. Then tab Rifaximin 550 mg twice daily along with standard prescription i.e. Lactulose 30 to 60 ml in two to three divided doses per day was given to each patient and efficacy was noted. Statistical analysis was carried out using SPSS version 20.0. Age, duration of disease and Conn’s score was presented as mean and standard deviation. A p value = 0.05 was considered as significant Results: Age range in our study was from 25 to 65 years with a mean of 45.73 ± 8.13 years. Most of the patients 54 (51.92%) were between 46 to 65 years of age range. Out of the 104 patients, 77 (74.04%) were male and male to female ratio was 2.9:1. Mean duration of disease was 13.66 ± 3.77 months. Mean conn’s score was 4.77 ± 1.43. Efficacy (no recurrence) of rifaximin in HE in chronic liver disease was found in 85 (81.73%) patients. Conclusion: It was inferred that rifaximin is useful in decreasing the recurrence of HE in chronic liver disease patients with previous episode/s of encephalopathy

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