scholarly journals Predicting Adverse Outcomes in Chronic Kidney Disease Using Machine Learning Methods: Data from the Modification of Diet in Renal Disease

2017 ◽  
Vol 3 (4) ◽  
Author(s):  
Zeid Khitan ◽  
◽  
Anna P. Shapiro ◽  
Preeya T. Shah ◽  
Juan R. Sanabria ◽  
...  
Author(s):  
Guanghan Li ◽  
Jian Liu ◽  
Jingping Wu ◽  
Yan Tian ◽  
Liyong Ma ◽  
...  

Background: The incidence rate of renal disease is high which can cause end-stage renal disease. Ultrasound is a commonly used imaging method, including conventional ultrasound, color ultrasound, elastography etc. Machine learning is a potential method which has been widely used in clinical. Objective: To compare the diagnostic performance of different ultrasonic image measurement parameters for kidney diseases, and to compare different machine learning methods with human-reading method. Methods: 94 patients with pathologically diagnosed renal diseases and 109 normal controls were included in this study. The patients were examined by conventional ultrasound, color ultrasound and shear wave elasticity respectively. Ultrasonic data were analyzed by Support vector machine (SVM), random forest(RF), K-nearest neighbor (KNN) and artificial neural network (ANN), respectively, and compared with the human-reading method. Results: Only ultrasound elastography data have diagnostic value for renal diseases. The accuracy of SVM, RF, KNN and ANN methods are 80.98%,80.32%,78.03%and79.67% respectively, while the accuracy of human-reading is 78.33%. In the data of machine learning ultrasound elastography, the elastic hardness parameters of renal cortex are most important. Conclusion: Ultrasound elastography is of highest diagnostic value in machine learning for nephropathy,the diagnostic efficiency of machine learning method is slightly higher than that of human-reading method, and the diagnostic ability of SVM method is higher than other methods.


2008 ◽  
Vol 149 (15) ◽  
pp. 691-696
Author(s):  
Dániel Bereczki

Chronic kidney diseases and cardiovascular diseases have several common risk factors like hypertension and diabetes. In chronic renal disease stroke risk is several times higher than in the average population. The combination of classical risk factors and those characteristic of chronic kidney disease might explain this increased risk. Among acute cerebrovascular diseases intracerebral hemorrhages are more frequent than in those with normal kidney function. The outcome of stroke is worse in chronic kidney disease. The treatment of stroke (thrombolysis, antiplatelet and anticoagulant treatment, statins, etc.) is an area of clinical research in this patient group. There are no reliable data on the application of thrombolysis in acute stroke in patients with chronic renal disease. Aspirin might be administered. Carefulness, individual considerations and lower doses might be appropriate when using other treatments. The condition of the kidney as well as other associated diseases should be considered during administration of antihypertensive and lipid lowering medications.


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