scholarly journals Benefit of Sunitinib in the treatment of pulmonary primitive neuroectodermal tumors: a case report and literature review

Oncotarget ◽  
2016 ◽  
Vol 7 (52) ◽  
pp. 87543-87551 ◽  
Author(s):  
Chunhui Zhang ◽  
Jingchun Zhang ◽  
Guangyu Wang ◽  
Jiajia Xu ◽  
Yanlin Li ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Primitive Neuroectodermal Tumors ◽  
Neuroectodermal Tumors

Analysis of Clinical, Imaging, and Pathologic Features of 36 Patients with Primary Intraspinal Primitive Neuroectodermal Tumors: A Case Series and Literature Review

2021 ◽  
Author(s):  
Xuefeng Wei ◽  
Xu Zhang ◽  
Zimu Song ◽  
Feng Wang
Keyword(s):  
Literature Review ◽  
Single Case ◽  
Case Reports ◽  
Case Series ◽  
Subtotal Resection ◽  
Study Cohort ◽  
Primitive Neuroectodermal Tumors ◽  
Pathologic Features ◽  
Neuroectodermal Tumors ◽  
The Mean

Abstract Background and Study Aims Primary intraspinal primitive neuroectodermal tumors (PNETs) account for ∼0.4% of all intraspinal tumors, but information about these tumors in the medical literature is limited to single case reports. We report four cases of primary intraspinal PNETs and present a systematic literature review of the reported cases. Materials and Methods We retrospectively reviewed and analyzed the clinical data of 4 patients with primary intraspinal PNETs who underwent neurosurgical treatment at our clinic between January 2013 and January 2020, and of 32 cases reported in the literature. Results The female-to-male ratio was 2.6:1. The mean patient age was 21.42 ± 15.76 years (range: 1–60 years), and patients <36 years of age accounted for 83.30% of the study cohort. Progressive limb weakness and numbness were the chief symptoms (accounting for ∼55.6%). The mean complaint duration was 0.89 ± 0.66 months for males and 2.72 ± 3.82 months for females (p = 0.028). Epidural (41.7%) was the most common site, and thoracic (47.3%) was the most frequent location. Most PNETs were peripheral, and magnetic resonance imaging (MRI) appearance was isointense or mildly hypointense on T1-weighted images and hyperintense on T2-weighted images. Homogeneous contrast enhancement was observed. The 1-year survival rate of patients who underwent chemoradiation after total or subtotal lesion resection was better compared with patients who did not undergo chemotherapy, radiotherapy, or total or subtotal resection. The modality of treatment was associated with survival time (p = 0.007). Conclusion Primary intraspinal PNETs mainly occur in young people with a female preponderance. In patients with a rapid loss of lower limb muscle strength and large intraspinal lesions on MRI, PNETs should be considered. Surgical resection and adjuvant radio chemotherapy are key prognostic factors.

scholarly journals Primitive neuroectodermal tumor of the esophagus with metastasis in the pineal gland

2019 ◽  
Vol 07 (09) ◽  
pp. E1163-E1165
Author(s):  
Leonardo Blas Jhon ◽  
Paloma Sánchez-Fayos ◽  
Maria Jesus Martín Relloso ◽  
Daniel Calero Barón ◽  
Juan Carlos Porres Cubero
Keyword(s):  
Case Report ◽  
Pineal Gland ◽  
Disease Progression ◽  
Rare Case ◽  
Primitive Neuroectodermal Tumor ◽  
Malignant Neoplasms ◽  
Primitive Neuroectodermal Tumors ◽  
First Case ◽  
Neuroectodermal Tumors ◽  
Chemotherapeutic Treatment

AbstractPrimitive neuroectodermal tumors (PNET) are very rare tumors that belong to a family of malignant neoplasms of tiny round cells which are derived from the neural crest. This report discusses a rare case of an adult woman with esophageal PNET, confirmed by immunohistochemistry, that presented with metastasis to the pineal gland. To our knowledge, this is the first case report of a PNET with these features. Despite surgery and chemotherapeutic treatment, our case has shown disease progression.

scholarly journals Primary intracranial peripheral primitive neuroectodermal tumor in an adult patient with aphasia: a rare case report

2021 ◽  
Author(s):  
kazem ghaemi ◽  
mahdieh rajabi-moghaddam ◽  
Hamid Abbaszadeh
Keyword(s):  
Case Report ◽  
Adult Patient ◽  
Rare Case ◽  
Primitive Neuroectodermal Tumor ◽  
Chief Complaint ◽  
Peripheral Primitive Neuroectodermal Tumor ◽  
Primitive Neuroectodermal Tumors ◽  
Neuroectodermal Tumors ◽  
Rare Case Report ◽  
First Time

Primary intracranial primitive neuroectodermal tumors (PNETs) are extremely rare malignancies, affects children and adolescents with only 10 cases has been reported over 33 years old. we present a case of PNET in a 36 years old female patient with the chief complaint of aphasia for the first time

scholarly journals Primary Pulmonary Primitive Neuroectodermal Tumor: A Case Report and Literature Review

2020 ◽  
pp. 1-3
Author(s):  
Guzmán-Casta Jordi
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Chest Wall ◽  
Primitive Neuroectodermal Tumor ◽  
Lung Parenchyma ◽  
Round Cell ◽  
Primitive Neuroectodermal Tumors ◽  
Small Round Cell ◽  
Molecular Features ◽  
Neuroectodermal Tumors

Primitive Neuroectodermal Tumors (PNET) and Ewing Sarcoma (EWS) belong to the same family of malignant, small, round cell neoplasms of soft tissue or bone origin. Common locations for EWS-PNET include chest wall, pelvis, and extremities. EWSPNETs that arise in the lung parenchyma without chest wall involvement are extremely rare in adults. We report a case of EWS-PNET of the lung in an adult and review the distinct clinical, pathological, and molecular features of these tumors.

scholarly journals Primitive Neuroectodermal Tumor of the Pancreas: A Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Uirá Teixeira ◽  
Marcos Goldoni ◽  
Michelle Unterleider ◽  
João Diedrich ◽  
Diogo Balbinot ◽  
...  
Keyword(s):  
Case Report ◽  
Primitive Neuroectodermal Tumor ◽  
Neuroectodermal Tumor ◽  
Neuroendocrine Cells ◽  
Malignant Neoplasms ◽  
Review Of The Literature ◽  
Primitive Neuroectodermal Tumors ◽  
Neuroectodermal Tumors

Primitive neuroectodermal tumors (PNETs) are presented as rare malignant neoplasms. In unusual cases, those neoplasms may arise in solid organs containing neuroendocrine cells, such as the pancreas. Herein the case of a 28-year-old patient that underwent gastroduodenopancreatectomy after the diagnosis of a huge mass (PNET) located in both head and body of the pancreas is reported. This is the 19th case of pancreatic PNET reported in literature.

Cytogenetic and histopathologic studies of congenital supratentorial primitive neuroectodermal tumors: A case report

2001 ◽  
Vol 7 (1) ◽  
pp. 67-71 ◽  
Author(s):  
Hermann J. Girschick ◽  
Rüdiger Klein ◽  
Wolfram G. Scheurlen ◽  
Joachim Kühl
Keyword(s):  
Case Report ◽  
Primitive Neuroectodermal Tumors ◽  
Neuroectodermal Tumors

scholarly journals Extraneural Supratentorial Primitive Neuroectodermal Tumor Metastasis: An Adult Case Report

2017 ◽  
Vol 06 (03) ◽  
pp. 210-212 ◽  
Author(s):  
Nidhal Matar ◽  
Kamel Bahri ◽  
Jallel Kallel ◽  
Adnene Boubaker ◽  
Hafedh Jemel
Keyword(s):  
Case Report ◽  
Tumor Metastasis ◽  
Primitive Neuroectodermal Tumor ◽  
Neuroectodermal Tumor ◽  
Adult Case ◽  
Primitive Neuroectodermal Tumors ◽  
Extraneural Metastases ◽  
Supratentorial Primitive Neuroectodermal Tumor ◽  
Neuroectodermal Tumors ◽  
Sporadic Cases

AbstractExtraneural metastases of supratentorial primitive neuroectodermal tumors (PNET) are very rare and have been reported in only sporadic cases. We present a patient with supratentorial PNET metastasizing to the lung, diagnosed 4 months after cerebral surgery.

Sign in / Sign up

Export Citation Format

Share Document