scholarly journals Determination of Quality of life in patients with chronic renal disease undergoing hemodialysis; a tertiary care experience

2018 ◽  
Vol 7 (1) ◽  
Author(s):  
Muhammad Tayyab Shera ◽  
Syeda Beenish Bareeqa ◽  
Syed Ijlal Ahmed ◽  
Syeda Sana Samar ◽  
Muhammad Mishkat Junaid ◽  
...  

<p align="justify"><strong><em>OBJECTIVE: </em></strong><em>Our objective is to determine the quality of life in chronic renal disease patients, to evaluate the pros and cons of dialysis in improving the QOL and to suggest an improved system of healthcare services provided to the patients.</em><em></em></p><p align="justify"><strong><em>INTRODUCTION: </em></strong><em>Chronic kidney disease (CKD), also known as chronic renal disease, is a progressive loss in renal function over a period of months or years. In medicine, Dialysis</em><strong><em> </em></strong><em>is a process for removing waste and excess water from the blood, and is used primarily as an artificial replacement for lost kidney function in people with renal failure. Chronic renal disease has many complications which can decrease the Quality of Life.</em><em></em></p><p align="justify"><strong><em>MATERIAL AND METHODS: </em></strong><em>A prospective case control study was conducted on 40 patients admitted to urology department of Mayo Hospital, Lahore for hemodylasis. </em><em>Data was collected on a preformed questionnaire of WHO about quality of life. Some demographic variables like age, education and income of the patient were added to the standard WHOQoL questionnaire.</em><em></em></p><p align="justify"><strong><em>RESULTS: </em></strong><em>WHOQoL questionnaire for both case and control groups had a significant p-value in four domains including overall quality of life (p=0.001), physical health (p=0.001), psychological health (p=0.001) and environmental health (p=0.001).</em><em></em></p><p align="justify"><strong><em>CONCLUSION: </em></strong><em>CKD treatment and in particular dialysis can decrease the quality of life due to multiple effects. The major aspects of life affected in an individual undergoing dialysis are physical health, psychological health and environmental health.</em><em></em></p><p align="justify"> </p>

2017 ◽  
Vol 29 (1) ◽  
pp. 30-34 ◽  
Author(s):  
Mir Hasan Shakil Mahmud ◽  
Bushra Yeasmin ◽  
Shipra Mandal

Schizophrenia is one of the major mental disorders which affect individual’s thinking ability, social interaction or attention. It affects person’s entire quality of life. The purpose of the study was to find out the quality of life of schizophrenic patient in Bangladesh. Cross sectional study design was used to conduct this study. The convenient sampling procedure was used throughout the process of participant’s selection and the numbers of respondents were 83. The study was carried out at National Institute of Mental Health and Hospital (NIMH), Dhaka. Data was collected by using face to face interview with a structured questionnaire WHOQOL-BREF (The World Health Organization Quality of Life- BREF) scale. It was found that most of the participants lead poor to moderate quality of life in four domains of the WHOQOL-BREF scale. Results showed that mean scores were for physical health (mean 2.7, SD+0.106); psychological health (mean 2.108, SD +0.0787); social relationship (mean 2.226; SD+0.116) and environmental health (mean 2.47; SD+0.077).This study indicated that, quality of life poor on psychological domain. It was also found statistically significance with age and social relationship domain (p value 0.005< 0.05); marital status and physical health domain (p value 0.004<0.05); educational level and physical health domain (p value 0.005<0.05) and environmental health domain (p value 0.025<0.05). There were no statistically significant difference between gender and other variables. Schizophrenia affects all aspects of person’s life such as physically, psychologically, socially and economically. Schizophrenic patients as well as their family members led very poor quality of life.Bang J Psychiatry June 2015; 29(1): 30-34


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Shanquan Chen ◽  
Jingxuan Wang ◽  
Jianfeng Zhu ◽  
Roger Yat-Nork Chung ◽  
Dong Dong

Abstract Background Pompe disease (PD) is a rare inherited disorder caused by the deficiency of acid-α glucosidase, which leads to the impairment of organ and tissue functions and causes disabilities. As the first national survey on patients with late-onset PD (LOPD) in China, this study investigated the quality of life (QOL) of adult patients with LOPD in China and explored its contributors. Methods Data were derived from a nation-based, cross-sectional, self-response survey on rare diseases (RDs) in early 2018. Answers from 68 adult Chinese patients with LOPD were used for data analysis. QOL was measured using the World Health Organization Quality of Life: Brief Version. Covariates included age, gender, education, employment, reliance on assistive devices, medication history, social support, and disease economic burden. Data were analyzed using linear regression in R. Results For adult patients with LOPD, the average scores and standard deviations (SD) of the four dimensions of QOL were physical health = 33.77 (SD = 18.28), psychological health = 43.81 (SD = 21.70), environmental health = 39.43 (SD = 16.93), and social relationship = 46.20 (SD = 19.76); the scoring for each dimension was evaluated on a scale of 0 to 100. At the significance level of p < 0.05, with increasing age, the patients experienced a significant decrease in physical health QOL (β = − 0.75) and environmental health QOL (β = − 0.79). Those who relied heavily on assistive devices had lower perceived physical health (β = − 17.8), psychological health (β = − 22.76), environmental health (β = − 17.8), and social relationships (β = − 22.12) than those who did not. A one-unit increase in the amount of social support, as a form of social interaction, led to a significant increase in physical health (β = 0.28), psychological health (β = 0.71), environmental health (β = 0.72), and social relationships (β = 0.70). Conclusion Adult Chinese patients with LOPD had a lower physical health and QOL compared to their counterparts with other RDs. Being employed was found to affect the QOL of adult Chinese patients with LOPD in almost all dimensions. Encouraging adult Chinese patients with LOPD to be socially active and help them become more involved in social life might improve their QOL.


2021 ◽  
Author(s):  
Shanquan Chen ◽  
Jingxuan Wang ◽  
Jianfeng Zhu ◽  
Roger Yat-Nork Chung ◽  
Dong Dong

Abstract Background: Pompe disease (PD) is a rare inherited disorder caused by the deficiency of acid-ɑ glucosidase, which leads to the impairment of organ and tissue functions and causes disabilities. As the first national survey on patients with late-onset PD (LOPD) in China, this study investigated the quality of life (QOL) of adult patients with LOPD in China and explored its contributors. Methods: Data were derived from a nation-based, cross-sectional, self-response survey on rare diseases in early 2018. Answers from 68 adult Chinese patients with LOPD were used for data analysis. QOL was measured using the World Health Organization Quality of Life: Brief Version (WHOQOL-BREF). Covariates included age, gender, education, employment, reliance on assistive devices, medication history, social support, and disease economic burden. Data were analyzed using linear regression in R.Results: For adult patients with LOPD, the average scores and standard deviations (SD) of the four dimensions of QOL were physical health=33.77 (SD=18.28), psychological health=43.81 (SD=21.70), environmental health=39.43 (SD=16.93), and social relationship=46.20 (SD=19.76); the scoring for each dimension was evaluated on a scale of 0 to 100. At the significance level of p<0.05, with increasing age, the patients experienced a significant decrease in physical health QOL (β=-0.75) and environmental health QOL (β=-0.79). Those who relied heavily on assistive devices had lower perceived physical health (β=-17.8), psychological health (β=-22.76), environmental health (β=-17.8), and social relationships (β=-22.12) than those who did not. A one-unit increase in the amount of social support, as a form of social interaction, led to a significant increase in physical health (β=0.28), psychological health (β=0.71), environmental health (β=0.72), and social relationships (β =0.70).Conclusion: Adult Chinese patients with LOPD had a lower physical health and QOL compared to their counterparts with other rare diseases. Being employed was found to affect the QOL of adult Chinese patients with LOPD in almost all dimensions. Encouraging adult Chinese patients with LOPD to be socially active and help them become more involved in social life might improve their QOL.


2008 ◽  
Vol 47 (169) ◽  
Author(s):  
Shailendra Shrestha ◽  
L R Ghotekar ◽  
S K Sharma ◽  
P M Shangwa ◽  
P Karki

This study was conducted to measure quality of life of patients with end stage renal disease ondifferent modalities of treatment.A total of 30 diagnosed cases of end stage renal disease (ESRD) attending BPKIHS were includedin the study. Group 1 included 10 patients on regular maintenance hemodialysis, group 2 included10 patients on continuous ambulatory peritoneal dialysis (CAPD) and group 3 included 10 patientson regular conservative drugs. The inclusion criteria were all diagnosed cases of ESRD based on theguidelines given by K/DOQI, 2002. A detailed history relating to the disease condition as per thedesigned proforma was taken, which included demographic data and clinical characteristics of thepatients. For assessment of quality of life, KDQOL-SF questionnaire was used. Strata 8.0 softwareprogram was used for the analysis of collected data.Physical health was found to be the most severely affected domain of the KDQOL. The mean scorefor physical health was least in group 1 (33.36 ± 16.14). Mental health was better in group 2 (54.93± 9.92) than in group 1 (39.50 ± 14.27) ( “p” value 0.01). Variables like haemoglobin, hematocrit andadequacy of dialysis have positive correlation with all the four domains of the KDQOL. There wasa statistically signifi cant correlation of physical health with mental health (p value 0.001), physicalhealth with kidney disease issues (p value 0.001) and mental health with kidney disease issues (pvalue 0.007).Our study has shown that patients of ESRD have a poor quality of life despite being in some formof dialysis and the most affected domain of the KDQOL scale is physical health. Patients on CAPDhave better quality of life than patients on maintenance haemodialysis especially in terms of mentalhealth. Variables like haemoglobin, hematocrit and adequacy of dialysis have a positive correlationwith all the four domains of the KDQOL scale i.e. optimizing these variables improves the overallquality of life.Key Words: dialysis, end stage renal disease, quality of lifeCorrespondence:


Author(s):  
Dr Bakul Gupta

Background: Various studies have shown the association between dyslipidemia and cardio-vascular risk among patients of chronic renal disease but the association non-significant than patients with normal renal function. There was lack of evidence exists because patients with chronic renal disease were excluded from the major clinical studies where the association with that target dyslipidemia treatment was being evaluated Material & Methods: The present prospective study was conducted among the patients of Chronic Kidney Disease above 18 years of age and diagnosed on the basis of history, detailed clinical examination, and biochemical and sonological examination based upon National Kidney Foundation (NKF) criteria were enrolled into the study. Clearance from hospital ethics committee was taken before start of study. Written informed consent was taken from each study participant. Results:  In the present study out of total study participants of chronic kidney disease 46% were in the 3rd stage of CKD, 38% were in the 4th stage of CKD and 16% were in the 5th stage of CKD. Out of total study participants of chronic kidney disease, 82% were managed by conservative treatment and 18% were being managed by hemodialysis. Out of total study participants of chronic kidney disease, 38% had normal lipid profile while 62% patients had dyslipidemia. We found statistically significant (p value < 0.05) association between dyslipidemia and hemodialysis and association between dyslipidemia and stages of chronic kidney disease was statistically non- significant (p value > 0.05). Conclusion:  We concluded from the present study that dyslipidemia is significantly associated as an additional risk factor in patients of Chronic Kidney Disease. We found significant association of hemodialysis with abnormal lipid profile. Key words: Chronic kidney disease, dyslipidemia, hemodialysis.


2018 ◽  
Vol 75 (3) ◽  
pp. 246-252
Author(s):  
Gora Miljanovic ◽  
Milan Marjanovic ◽  
Sonja Radakovic ◽  
Miljojko Janosevic ◽  
Tatjana Mraovic ◽  
...  

Background/Aim. Chronic renal disease is one of the growing problems all over the world. Health-related quality of life (HRQoL) is an important indicator for those with a chronic disease, such as chronic renal disease, because it may serve as predictor of mortality and hospitalization. The aim of this study was to assess HRQoL in patients on chronic maintenance hemodialysis (HD), and compare it with patients suffering from hypertension (HTA), and normal controls of the same age and gender (C). Methods. The study enrolled 224 males and females older than 18 years: 67 in the HD group, 78 in the HTA group, and 79 in the C group. HRQoL was assessed in all groups using 15-D questionnaire. Results. Significantly higher level of education was recorded in the HD group compared to other two groups. In the HD group there were significantly less employed persons (9%) and significantly more retired (67.2%). All groups were similar regarding an average monthly income and marital status. We found significantly lower total HRQoL score in patients in the HD group, compared to normal controls (0.78 ? 0.16 vs. 0.89 ? 0.10 in the HTA and 0.95 ? 0.06 in the C group) as well as specific scores in almost all investigated domains, except in speech, eating and mental functions. Patients in the HD and HTA groups had similar self-reported quality of life in additional 3 domains: hearing, elimination and distress, while the HD group reported significantly lower scores in remaining 9 domains: mobility, vision, breathing, sleeping, usual activities, discomfort and symptoms, depression, vitality and sexual activity. Patients in the HTA group had significantly lower scores than normal controls in 8 domains (hearing, sleeping, elimination, usual activities, discomfort and symptoms, depression, distress and vitality) as well as in total quality of life, while in remaining 4 domains there was no significant difference (mobility, vision, breathing, sexual activity). Conclusion. Both investigated chronic diseases lead to impairment of HRQoL, which is substantially stronger in hemodialysis than in hypertension. Considering the relationship between depression and HRQoL measures, it may be useful to treat depression of HD patients in order to improve their quality of life.


2021 ◽  
Vol 60 (2) ◽  
pp. 124-130
Author(s):  
Dagmar Nemček ◽  
Patrícia Shtin Baňárová ◽  
Petra Kurková

Abstract Objective The objective of the study was to analyse and compare the subjective quality of life (S-QoL) of women with physical disabilities (PDs) through satisfaction with the quality of life domains and the overall quality of life assessment. Methods The sample comprised of women with PDs (n=137), divided into 4 age categories: 19-29 yrs. (n=53); 30-44 yrs. (n=25); 45-59 yrs. (n=24) and over 60 yrs. (n=35). The Subjective Quality of Life Analyses questionnaire and the WHO User Manual were used as a primary research method. The Wilcoxon Signed Rank Test was used to assess the differences between QoLDs, Kruskal Wallis test to assess differences in S-QoL among four independent groups and Mann Whitney U-test between two age categories. Results The highest satisfaction in all age categories of women was found in the social relations domain, and in the 19-29 yr-old women equally in the social relations and physical health domains. The highest dissatisfaction was reported with the psychological health and environment domains. The key finding is that the main differences are between the youngest category (aged 19-29 yrs) and the three older categories with regard to physical health, environment and overall QoL. Conclusions It is necessary to continue this line of research with a greater focus on exploring the ways in which the psychological health domain can be improved as an integral part of S-QoL, and to also focus on the QoL indicators that make up the environment domain and search for ways to enhance these.


Facilities ◽  
2017 ◽  
Vol 35 (5/6) ◽  
pp. 270-285 ◽  
Author(s):  
Mei-yung Leung ◽  
Ibukun Oluwadara Famakin ◽  
Paul Olomolaiye

Purpose Quality of life (QoL) for elderly residents of care and attention (C&A) homes has become an important consideration, given the increasingly aging population. Due to the number of hours such residents spend indoors, the quality of the facilities can contribute to their day-to-day QoL. This study aims to investigate the effect of facilities management (FM) on the QoL of Chinese elderly people living in C&A homes. Design/methodology/approach A survey of perceived satisfaction with the components of FM and QoL was carried out with a sample of residents. A total of 18 FM components and five QoL domains, including physical health, independence, psychological health, social relationships and living environment, as well as overall QoL, were identified. Findings The findings show that physical health is influenced by accessibility, doors and windows and signage; independence can be improved by enhancing accessibility, water supply, lighting and ventilation; accessibility, water supply, distance and doors and windows all predict psychological health; social relationships are improved by lighting and ventilation; distance impacts positively on the living environment; and overall QoL is predicted by lighting, ventilation, accessibility, doors and windows, handrails, recreation and signage. Originality/value The study recommends that designers and facilities managers review the micro-climate settings to harness available natural lighting and ventilation, introduce bimetallic strips to the heating systems to maintain a suitable water temperature and install large, easy-to-understand and graphic signage for straightforward wayfinding in C&A homes.


2017 ◽  
Vol 16 (1) ◽  
pp. 14-18
Author(s):  
Sabina Shrestha ◽  
Aparajita Manoranjan ◽  
Sushan Man Shrestha

Introduction: Strabismus affects the quality of life of adults both in functional and psychosocial aspect of life. This study was conducted to compare the health related quality of life in adults before and after strabismus surgery.Methods: It was a prospective quantitative study conducted in Nepal Eye Hospital from Sep 2015 to July 2016. Thirty one adult participants with strabismus undergoing strabismus surgery completed the study. Twenty open ended adult strabismus questionnaire (AS-20) were used to assess the health related quality of life of adults before and one month after strabismus surgery.Results: The overall median score of adult strabismus questionnaire for quality of life improved from 68.75 (Interquartile range (IQR 25) to 91.25 (IQR 17.5) after strabismus surgery (p value < 0.00). Similarly, the median function subscale and median psychosocial subscale also improved from 72 (IQR 25) to 95 (10) and from 55 (IQR 37.5) to 90 (IQR 15) respectively after surgery. Conclusion: The quality of life of adult strabismic patients improved significantly after stabismus surgery.


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