scholarly journals CIRCADIAN BLOOD PRESSURE PROFILE IN YOUNG SUBJECTS WITH PRE-HYPERTENSION

2013 ◽  
Vol 19 (3) ◽  
pp. 263-269 ◽  
Author(s):  
M. E. Evsevyeva ◽  
E. A. Mishchenko ◽  
M. V. Rostovtseva ◽  
I. Y. Galkova ◽  
E. V. Chudnovsky ◽  
...  

and arterial hypertension for the planning of timely and effective prevention. Design and methods.We enrolled 147 people: with optimal and normal BP — 81, with high normal BP — 30 men, and 36 controls. Ambulatory BP monitoring (ABPM) nas performed in the offi ce at the setting of ≪typical working day≫ or 24 +- 1,5 hours with 15 and 30 minute intervals between the measurements during the day and night, respectively.Results.Young people with high normal BP differ from the subjects with normal and optimal BP by a variety of ABPM indices. However, the changes are lower, but similar to those observed in patients with evident hypertension, including increase of mean systolic and diastolic BP, time index of systolic and diastolic BP, and morning BP surge. Young men with high normal BP are also characterized by the family history of the early cardiovascular disease and the presence of cardiocerebral complaints with the frequency similar to that in hypertensive subjects.Conclusions.Young subjects with high normal BP seem to be at higher risk, and should undergo early and effective preventive measures.

2010 ◽  
Vol 16 (3) ◽  
pp. 270-276
Author(s):  
M. E. Evsevieva ◽  
O. V. Sergeeva ◽  
G. P. Niculina ◽  
M. V. Baturina ◽  
S. V. Pamukche ◽  
...  

Objective. To assess the incidence of different variants of arterial hypertension (AH) among students daily BP regulation. Design and methods. 234 students of Stavropol State Medical Academy of both sexes aged 18-23 years (middle age 21,4  0,2 years) were examined, among them 73 men and 161 women. Physical examination and blood pressure (BP) measuring by traditional and monitor methods were performed. For statistical analysis software package STATISTICA, version 6,0 was used. Results. 10,7 % (25 people) of students had isolated offi ce AH and 11,5 % (27 people) had latent AH. Subjects having any type of labile AH demonstrated an increase of daily systolic and diastolic BP and an elevation of mean hemodynamic and pulse BP that has negative predictive value, they also showed an increase of pathological daily profi le rate. Conclusions. About a quarter of young people have various forms of AH that can be diagnosed by only use of 24-hour BP monitoring. They need an active follow-up at the centers of students health.


Cardiology ◽  
2016 ◽  
Vol 136 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Akinori Sawamura ◽  
Takahiro Okumura ◽  
Kyosuke Takeshita ◽  
Naoki Watanabe ◽  
Naoaki Kano ◽  
...  

Objectives: An abnormal circadian blood pressure (BP) profile is considered a risk factor for cardiovascular disease. However, its significance in heart failure patients with nonischemic etiology is unknown. Herein, we investigated the prognostic value of a circadian BP profile in patients with nonischemic dilated cardiomyopathy (NIDCM). Methods: We enrolled 114 NIDCM patients (76 males, mean age 53.1 years). The percent nighttime BP fall (%NBPF) was defined using ambulatory BP monitoring as a percent decrease in mean systolic BP in nighttime from daytime. All patients were divided into three groups: dipper (%NBPF ≥10), non-dipper (0 ≤ %NBPF < 10), and riser (%NBPF <0). Results: Riser patients had the highest serum creatinine levels (dipper, 0.78 ± 0.20 mg/dl; non-dipper, 0.85 ± 0.21 mg/dl; riser, 0.99 ± 0.23 mg/dl; p = 0.006). In survival analysis, riser patients had the highest cumulative cardiac-related deaths (log-rank, p = 0.001), which was an independent predictor of cardiac-related deaths (hazard ratio, 12.6; 95% confidence interval, 1.76-253; p = 0.01). Multivariate analysis revealed that the norepinephrine level at 24-hour collected urine (24 h U-NE) and the serum creatinine level were independent determinants of %NBPF (adjusted R2 = 0.20; 24 h U-NE, p = 0.0001; serum creatinine, p = 0.04). Conclusions: The riser profile was associated with poor prognosis of NIDCM, which may reflect impaired sympathetic nervous system activity. Evaluating the circadian BP profile may be useful for risk stratification in NIDCM patients.


2006 ◽  
Vol 1073 (1) ◽  
pp. 79-85 ◽  
Author(s):  
E. DABROWSKA ◽  
J. LEWANDOWSKI ◽  
P. JEDRUSIK ◽  
B. SYMONIDES ◽  
B. WOCIAL ◽  
...  

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
M I Smirnova ◽  
V M Gorbunov ◽  
D A Volkov ◽  
Y N Koshelyaevskaya ◽  
A D Deev ◽  
...  

Abstract Background Masked hypertension (MH) is associated with cardiovascular complications and poor prognosis. Characteristics of untreated patients with reproducible MH are studied insufficiently. Purpose The aim of our study was to assess characteristics of ambulatory patients with reproducible MH in comparison to patients with non-reproducible MH in two visits. Methods The patients from the ambulatory BP monitoring (ABPM) database (>2000 patients) were selected according to the following criteria: absence of any antihypertensive treatment (AHT), availability of clinical BP (CBP) and ABPM records at two visits with the 6 months interval, CBP<140 and 90 mmHg at both visits, availability of clinical, anthropometric data and history. MH criteria in each patients should be present at least at one of the visits. ABPM was performed by the oscillometric device equipped with software for arterial stiffness calculation. The standard statistical methods and analysis of variance (ANOVA) were used. Results We selected 295 patients (men 43%, mean age 49.0±7.6 years, CBP 128.4±9.4/80.5±7.2 mm Hg, body mass index 27.6±4.3 kg/m2, 24h pulse wave velocity in aorta [PWV] 10.7±1.7 m/s). MH only at one visit was found in 168 patients (56.9%). Respectively, MH at both visits was in 127 patients (43.1%). The patients with reproducible MH were characterized by the presence of: mother's (p=0.011) or father's hypertension (p=0.025), mother's ischemic heart disease (p=0.015), mother's myocardial infarction (p=0.020), father's stroke (p=0.030), higher arterial stiffness (PWV 11.0±1.7 m/s vs. 10.5±1.8 m/s, p=0.022), and systolic BP in aorta (120.0±7.5 mmHg vs. 117.8±9.4 mm Hg). Conclusions The patients with reproducible MH (without AHT) are characterized most of all by the family history of hypertension and its complications. The correlation of stable MH with arterial stiffness confirms the importance of PWV and central aortic pressure measurement in patients with CBP<140 and 90 mmHg.


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