Annotation. This article highlights the issues of workers’ industrial medical rehabilitation, one of the leading professions of railway transport who had already had COVID 19. There is a main aspect is the data of the studies carried out for the period 2020-2021 there on the basis of the Center for Restorative Medicine and Rehabilitation of the Private Healthcare Institution KB "Russian Railways-Medicine" Yekaterinburg and the Clinical Hospital of the ChUZ of Perm together with the Department of Faculty Therapy No. 2 of Occupational Pathology and Clinical Laboratory Diagnostics of PSMU im. Wagner. Proceeding from the fact that the institutions of Russian Railways-Medicine are the main link in maintaining the health of the transport system of JSC Russian Railways employees. Methods: On the basis of the rehabilitation department in Yekaterinburg, express questionnaires about quality of life were developed and implemented for JSC Russian Railways employees after this disease. The questionnaires included a subjective assessment of the physiological, psychological, and emotional state of Russian Railways employees (able-bodied) who had recovered in the near future and those who had not more than six months after the illness. The total number of people who have recovered since the beginning of the pandemic is about 4,000. The questionnaires received on feedback from 761 people were processed. In the structure of the interviewed by gender: male - 47%, female - 53%, respondents who have had mild and moderate forms of a new coronavirus infection (COVID-19). In the research and analysis of the material obtained, the criteria for selection for rehabilitation were identified, taking into account age and gender status, as well as the need for rehabilitation measures. The obtained data were compared with the research data of the Department of Faculty Therapy No. 2, Occupational Pathology and Clinical Laboratory Diagnostics of the Vagner State Medical Academy, Perm. Results: The study results are used in the development of rehabilitation programs and are also aimed at reducing industrial risks and hazards arising in the railway transport when performing functions by employees of locomotive crews who returned to production activities in the early period after this infection. Since, in combination with postcovid symptoms, the influence of production factors, the “specificity of the human factor”, can lead to serious consequences, both in health and in the performance of their labor duties on the infrastructure of railway transport, which is an increased danger zone. We have found that rehabilitation measures must be carried out for all employees of Russian Railways who have been ill, regardless of gender, age and degree of lung damage. In our opinion, an important marker for the understanding of functional disorders in postcoid symptomatology is the neutropicity of the virus, its penetration and damage to the limbic system, those important departments responsible for the regulation of general changes in brain activation that affect the integrity of functioning.