Prevalence of Pulmonary Hypertension in Dogs with Degenerative Mitral Valve Disease

The study was conducted to record the various clinical, electrocardiographic, radiographic and echocardiographic changes in dogs with Pulmonary Hypertension (PH) due to mitral valve disease (MVD). Among the MVD, dogs 15.5 per cent, 8.7 per cent and 4.8 per cent had mild PH, moderate PH and severe PH respectively. A highly significant increase in tricuspid regurgitation velocity (greater than 2.5 mm/Hg), tricuspid regurgitation peak gradient (greater than 25 mm Hg), was recorded in dogs with mild, moderate and severe PH due to MVD when compared to their disease control. A highly significant increase in of MPA/Ao (greater than 0.8) ratio was recorded in dogs with various degree of PH (mild, moderate and severe) when compared with dogs without PH. According to the severity tricuspid regurgitation flow pattern in the right atrium during systole was recorded in all these dogs. In dogs with MVD, moderate to severe PH worsens outcome.

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Correction to: Outcome of MC3 ring annuloplasty for moderate and severe functional tricuspid regurgitation associated with rheumatic mitral valve disease

The Cardiothoracic Surgeon ◽

10.1186/s43057-019-0010-z ◽

2019 ◽

Vol 27 (1) ◽

Author(s):

Shady Eid Al-Elwany ◽

Yasser Shaban Mubarak ◽

Yasser Ali Kamal

Keyword(s):

Mitral Valve ◽

Tricuspid Regurgitation ◽

Mitral Valve Disease ◽

Valve Disease ◽

Functional Tricuspid Regurgitation ◽

Ring Annuloplasty

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Impact of tricuspid repair on surgical death in patients undergoing mitral valve surgery due to rheumatic disease

European Heart Journal ◽

10.1093/eurheartj/ehab724.2258 ◽

2021 ◽

Vol 42 (Supplement_1) ◽

Author(s):

T Viana ◽

R M Vieira De Melo ◽

D N V Da Silva ◽

G P Santana ◽

M L N De Paula ◽

...

Keyword(s):

Cardiac Surgery ◽

Mitral Valve ◽

Tricuspid Regurgitation ◽

Mitral Valve Disease ◽

Right Heart Failure ◽

Valve Disease ◽

Surgical Mortality ◽

Tricuspid Annuloplasty ◽

The Impact ◽

Tricuspid Repair

Abstract Introduction Observational studies differ on the impact of performing tricuspid repair on surgical mortality. Some studies demonstrate increased surgical mortality related to right ventricular failure and circulatory shock, while there are other studies that evidence improvement in quality of life and signs of right heart failure in the long time. Objective To evaluate the impact on surgical mortality of concomitant tricuspid annuloplasty in patients undergoing cardiac surgery for rheumatic mitral valve disease, who have moderate to severe tricuspid regurgitation. Methods This is a prospective cohort from January 1, 2017 to December 30, 2020. All patients over 18 years of age who underwent cardiac surgery to correct rheumatic mitral valve disease with moderate to significant tricuspid regurgitation were included. The primary outcome was 30-days mortality. Results 165 patients were included, 98 (59.4%) underwent tricuspid valve annuloplasty. The mean age was 46, 5 (±12) years, the median of Euroscore II was 2,33%. The 30-days mortality was 17 (10.3%) and there was no difference between the groups submitted or not to tricuspid repair: 12 (12.2%) versus 5 (7.5%); p=0.44, respectively. In the multivariate analysis involving seven variables with a potential prediction of death in 30 days, tricuspid repair had no association with death, RR 2,4 (0,5 – 8,3); p=0.27. Conclusion In patients with rheumatic heart disease undergoing cardiac surgery for rheumatic mitral valve disease, perform tricuspid annuloplasty in individuals who had moderate to severe tricuspid insufficiency was not associated with increased surgical mortality. FUNDunding Acknowledgement Type of funding sources: None.

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Use of Prostaglandin E1 to Treat Peri-Anaesthetic Pulmonary Hypertension Associated with Mitral Valve Disease

Journal of International Medical Research ◽

10.1177/030006059302100308 ◽

1993 ◽

Vol 21 (3) ◽

pp. 161-164 ◽

Cited By ~ 4

Author(s):

K Mikawa ◽

N Maekawa ◽

R Goto ◽

H Yaku ◽

K Nishina ◽

...

Keyword(s):

Pulmonary Hypertension ◽

Mitral Valve ◽

Glyceryl Trinitrate ◽

Mitral Valve Disease ◽

Prostaglandin E1 ◽

Valve Disease ◽

Prostaglandin E ◽

Severe Pulmonary Hypertension ◽

Critical Problem ◽

Ventricular Afterload

Severe pulmonary hypertension (PH) can be a critical problem during and after cardiac surgery, since it increases right ventricular afterload resulting in decreased cardiac output. A case of pulmonary hypertension associated with mitral valve disease and resistant to glyceryl trinitrate therapy during surgery is reported. The case was treated successfully with prostaglandin E1 (PGE1), indicating that PGE1 can be used peri-operatively in a patient with refractory PH resistant to glyceryl trinitrate treatment.

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