Valvular heart diseases. Ultrastructural study of right ventricular myocardium in tricuspid regurgitation associated with rheumatic mitral valve disease.

1991 ◽  
Vol 20 (5) ◽  
pp. 976-978
Author(s):  
S. Imai
Keyword(s):  
Mitral Valve ◽  
Right Ventricular ◽  
Ultrastructural Study ◽  
Tricuspid Regurgitation ◽  
Mitral Valve Disease ◽  
Heart Diseases ◽  
Ventricular Myocardium ◽  
Valve Disease ◽  
Valvular Heart Diseases

scholarly journals Understanding right ventricular dysfunction and functional tricuspid regurgitation accompanying mitral valve disease

2013 ◽  
Vol 145 (5) ◽  
pp. 1234-1241.e5 ◽  
Author(s):  
Lina Maria Vargas Abello ◽  
Allan L. Klein ◽  
Thomas H. Marwick ◽  
Edward R. Nowicki ◽  
Jeevanantham Rajeswaran ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Right Ventricular ◽  
Tricuspid Regurgitation ◽  
Mitral Valve Disease ◽  
Ventricular Dysfunction ◽  
Right Ventricular Dysfunction ◽  
Valve Disease ◽  
Functional Tricuspid Regurgitation

scholarly journals Myxomatous Mitral Valve Disease with Mitral Valve Prolapse and Mitral Annular Disjunction: Clinical and Functional Significance of the Coincidence

2021 ◽  
Vol 8 (2) ◽  
pp. 9
Author(s):  
Nina C. Wunderlich ◽  
Siew Yen Ho ◽  
Nir Flint ◽  
Robert J. Siegel
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Morphological Changes ◽  
Morphological Characteristics ◽  
Mitral Annulus ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Valve Disease ◽  
Left Ventricular Myocardium ◽  
Basal Portion

The morphological changes that occur in myxomatous mitral valve disease (MMVD) involve various components, ultimately leading to the impairment of mitral valve (MV) function. In this context, intrinsic mitral annular abnormalities are increasingly recognized, such as a mitral annular disjunction (MAD), a specific anatomical abnormality whereby there is a distinct separation between the mitral annulus and the left atrial wall and the basal portion of the posterolateral left ventricular myocardium. In recent years, several studies have suggested that MAD contributes to myxomatous degeneration of the mitral leaflets, and there is growing evidence that MAD is associated with ventricular arrhythmias and sudden cardiac death. In this review, the morphological characteristics of MAD and imaging tools for diagnosis will be described, and the clinical and functional aspects of the coincidence of MAD and myxomatous MVP will be discussed.

Impact of tricuspid repair on surgical death in patients undergoing mitral valve surgery due to rheumatic disease

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
T Viana ◽  
R M Vieira De Melo ◽  
D N V Da Silva ◽  
G P Santana ◽  
M L N De Paula ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Mitral Valve ◽  
Tricuspid Regurgitation ◽  
Mitral Valve Disease ◽  
Right Heart Failure ◽  
Valve Disease ◽  
Surgical Mortality ◽  
Tricuspid Annuloplasty ◽  
The Impact ◽  
Tricuspid Repair

Abstract Introduction Observational studies differ on the impact of performing tricuspid repair on surgical mortality. Some studies demonstrate increased surgical mortality related to right ventricular failure and circulatory shock, while there are other studies that evidence improvement in quality of life and signs of right heart failure in the long time. Objective To evaluate the impact on surgical mortality of concomitant tricuspid annuloplasty in patients undergoing cardiac surgery for rheumatic mitral valve disease, who have moderate to severe tricuspid regurgitation. Methods This is a prospective cohort from January 1, 2017 to December 30, 2020. All patients over 18 years of age who underwent cardiac surgery to correct rheumatic mitral valve disease with moderate to significant tricuspid regurgitation were included. The primary outcome was 30-days mortality. Results 165 patients were included, 98 (59.4%) underwent tricuspid valve annuloplasty. The mean age was 46, 5 (±12) years, the median of Euroscore II was 2,33%. The 30-days mortality was 17 (10.3%) and there was no difference between the groups submitted or not to tricuspid repair: 12 (12.2%) versus 5 (7.5%); p=0.44, respectively. In the multivariate analysis involving seven variables with a potential prediction of death in 30 days, tricuspid repair had no association with death, RR 2,4 (0,5 – 8,3); p=0.27. Conclusion In patients with rheumatic heart disease undergoing cardiac surgery for rheumatic mitral valve disease, perform tricuspid annuloplasty in individuals who had moderate to severe tricuspid insufficiency was not associated with increased surgical mortality. FUNDunding Acknowledgement Type of funding sources: None.

scholarly journals Natural history of coexistent tricuspid regurgitation in patients with degenerative mitral valve disease: Implications for future guidelines

2014 ◽  
Vol 148 (6) ◽  
pp. 2802-2810 ◽  
Author(s):  
Andrew B. Goldstone ◽  
Jessica L. Howard ◽  
Jeffrey E. Cohen ◽  
John W. MacArthur ◽  
Pavan Atluri ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Natural History ◽  
Tricuspid Regurgitation ◽  
Mitral Valve Disease ◽  
Valve Disease ◽  
History Of

scholarly journals Diagnostic value of echocardiographic indices of left atrial and ventricular morphology in dogs with myxomatous mitral valve disease (MMVD)

2021 ◽  
Vol 4 (1) ◽  
pp. 16-23
Author(s):  
R. M. Trofimiak ◽  
L. G. Slivinska
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Left Atrial ◽  
Heart Diseases ◽  
Diagnostic Technique ◽  
Diagnostic Value ◽  
Left Ventricular ◽  
Clinical Diagnostics ◽  
Valve Disease ◽  
Mitral Apparatus

Myxomatous mitral valve disease (MMVD) is one of the most common acquired diseases of the cardiovascular system of genetic etiology in small breed dogs. A long asymptomatic course characterizes the disease. Presently, the main diagnostic technique for heart diseases is echocardiography. This study evaluates individual echocardiographic indices of the left atrial and ventricular morphology with the determination of the diagnostic value of each of them in predicting the course of the disease. The study was conducted in a private veterinary hospital “Eurovet” and on the basis of the clinic of the Department of internal animal diseases and clinical diagnostics of Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnology Lviv during 2018–2019. The objects consisted of 46 dogs with a confirmed diagnosis of myxomatous mitral valve disease according to the recommendations of the American College of Veterinary Internal Medicine (ACVIM) and no signs of comorbidities. During the study, three experimental groups of animals were formed according to the clinical and functional status characteristic of each stage of MMVD development – B1, B2, C. According to the results, all experimental dogs showed changes in the mitral apparatus in the form of thickening of the anterior and posterior cusps, mitral valve (MV) prolapse into the left atrial (LA) cavity and regurgitation (MR), the severity of which increased with the stage of the disease (from 20 % to 60 %). In 44.4 % of animals in group B2, thickening of the left ventricular walls was diagnosed in diastole and in 22.2 % in systole. Instead, these values increase to 46.1 % and 53.8 % in group C, respectively. However, the degree of hypertrophy is disproportionate. With the development of the disease, we detect its decrease from 0.64 ± 0.03 (group B1) to 0.50 ± 0.04 (group B2) and 0.51 ± 0.03 (group C) also we observed an increase in LVEDD/2 from 1.30 ± 0.05 cm (group B1) to 1.46 ± 0.12 cm (group B2) and 1.54 ± 0.13 cm (group C). The value of nLVEDD in B1 was 1.36 times (P < 0.001) lower compared to B2 and C. Higher values of this parameter were found in 23.1 % of dogs in group C compared to the maximum value of B2. As MV insufficiency progresses, the LA/Ao index increases slightly (1.08 times) in B2, followed by an increase in C (1.38 times, P < 0.001). At the same time, we diagnose an increase (P < 0.05) in PV/PA by 1.18 times in B2 and 1.46 times (P < 0.001) in C. Thus, an increase in the severity of mitral regurgitation, a rapid increase in nLVEDD, the dynamics of the decrease in the degree of hypertrophy h/R, as well as an increase in LA/AO, PV/PA indices are predictors of unfavorable prognosis of myxomatous degeneration of the mitral valve in dogs.

Should Moderate Functional Tricuspid Regurgitation Be Repaired During Surgery for Rheumatic Mitral Valve Disease?

2020 ◽  
Vol 29 (10) ◽  
pp. 1554-1560 ◽  
Author(s):  
Hosam F. Fawzy ◽  
Ahmed A. Morsy ◽  
Amro R. Serag ◽  
Mohamed S. Elkahwagy ◽  
Gamal Sami ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Tricuspid Regurgitation ◽  
Mitral Valve Disease ◽  
Valve Disease ◽  
Functional Tricuspid Regurgitation
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