scholarly journals The idiopathic form of Sweet's syndrome

2016 ◽  
Vol 19 (1) ◽  
pp. 27-31
Author(s):  
O. Yu Olisova ◽  
O. V Grabovskaya ◽  
N. P Teplyuk ◽  
Ekaterina V. Grekova ◽  
K. V Ignatieva

A clinical case of Sweet’s syndrome (dermatosis neutrophilica febrilis acuta) in a 59-year old man is presented. The data about etiology, pathogenesis and clinical picture are summarized. Difficulties in diagnosis of the disease are described. Sweet’s syndrome is characterized by skin lesions with marked neutrophilic infiltration. The syndrome manifests itself as a rash ofpainful red papules, plaxes, intradermal nodes on the head, neck and hands, multiple ostiofolliculitis. It is also characterized by fever, leukocytosis, arthralgias, episcleritis. Approximately 15% of cases are paraneoplastic. Patergiya can be seen in patients. It is a skin condition, characterized by lesions due to minor injuries. Diagnosis is based on a combination of clinical, physical, laboratory examinations and histological changes. The differential diagnosis should be made with exudative erythema multiforme, allergic vasculitis, erythema elevatum diutinum and erythema nodosum.

2013 ◽  
Vol 20 (3) ◽  
pp. 190
Author(s):  
Young Ho Seo ◽  
Young Ho Lee ◽  
Jong Dae Ji ◽  
Gwan Gyu Song ◽  
Seu Hee Yoo ◽  
...  

Dermatology ◽  
1983 ◽  
Vol 166 (4) ◽  
pp. 181-185 ◽  
Author(s):  
Kazuko Hamanaka ◽  
Kenji Ishizu ◽  
Sumiyoshi Takasugi ◽  
Naotika Toki

2019 ◽  
Vol 7 ◽  
pp. 232470961989516
Author(s):  
Arash Mollaeian ◽  
Hadi Roudsari ◽  
Ebrahim Talebi

Sweet’s syndrome, also known as acute febrile neutrophilic dermatosis, is a rare disorder that typically presents with rapid appearance of tender skin lesions accompanied by fever and leukocytosis with neutrophilia. Its pathogenesis is not fully understood. The syndrome is generally classified into classical, malignancy-associated, and drug-induced categories, each of which has its specific characteristics. In this article, we present a case of classical Sweet’s syndrome in a woman who presented with an acute viral illness.


2013 ◽  
Vol 52 (10) ◽  
pp. 1185-1188 ◽  
Author(s):  
Marie Caucanas ◽  
Alain Heylen ◽  
Florence Rolland ◽  
Gebhard Müller ◽  
Catherine Olemans ◽  
...  

2018 ◽  
Vol 28 (2) ◽  
pp. 196-198 ◽  
Author(s):  
Brigita D. Smolovic ◽  
Mirjana D. Gajic-Veljic ◽  
Milos M. Nikolic ◽  
Damir F. Muhovic

Objective: To present a case of relapsing and resistant Sweet’s syndrome that developed during pregnancy together with an onset of Crohn’s disease, showing complete resolution with the use of infliximab. Clinical Presentation and Intervention: A 30-year-old pregnant woman presented with fever, skin lesions, and diarrhea. Skin biopsy confirmed neutrophilic dermatosis and she was diagnosed with Crohn’s disease after endoscopy. There was no recurrence of Sweet’s syndrome outside of her pregnancy. During a previous pregnancy, while corticosteroids were ineffective, complete regression of skin lesions was achieved using infliximab. Conclusion: The “off-label” use of infliximab is beneficial for relapsing and resistant Sweet’s syndrome.


Ensho ◽  
1981 ◽  
Vol 2 (4) ◽  
pp. 357-358
Author(s):  
Kazuko Hamanaka ◽  
Kenji Ishizu ◽  
Naotika Toki ◽  
Sumiyoshi Takasugi

2012 ◽  
Vol 7 (3) ◽  
pp. 17-23
Author(s):  
S Bhattarai ◽  
A Rijal ◽  
SR Pandey ◽  
C Kharel

Sweet's syndrome (the eponym for acute febrile neutrophilic dermatosis) is characterized by a constellation of clinical symptoms, physical features, and pathologic findings which include fever, neutrophilia, tender erythematous skin lesions (papules, nodules, and plaques), and a diffuse infiltrate consisting predominantly of mature neutrophils that are typically located in the upper dermis without vasculitis. To study the clinico-pathological features, clinical course and treatment of patients with sweets syndrome. A retrospective observational analysis of 12 diagnosed cases of sweet’s syndrome attending and admitted in the Department of Dermatology from June 2003- April 2009 were considered in this study. The study comprised of 9 females and 3 males (3:1) between the age group of 22-73 years. Typical lesions of sweets syndrome were present in all cases and the duration of illness ranged from 3-8 days. Constitutional symptoms of fever, pain and malaise were present in all and the extremities were the most common site of involvement 12 (100%). Leucocytosis was present in 7 (58.3%), raised ESR in 9 (75%) and raised C reactive protein in 7(58.3%) patients. Characteristic histological features were recorded in specimens of all patients. 9 (75%) patients responded promptly to systemic oral corticosteroids while 3 (25%) were treated with intravenous steroids. Complete Response was seen in 7 (58.3%), partial response in 5 (41.6%) and recurrence in 1(8.3%) patient after therapy. Characteristic skin lesion, histopathological diagnosis and relevant abnormal laboratory parameters can act as a useful diagnostic tool in patients with sweet’s syndrome. DOI: http://dx.doi.org/10.3126/jcmsn.v7i3.6703 Journal of College of Medical Sciences-Nepal, 2011, Vol-7, No-3, 17-23


2020 ◽  
Vol 95 (5) ◽  
pp. 344-348
Author(s):  
Hak Soo Kim ◽  
Jung A Yoon ◽  
Je Whan Lee ◽  
Jai Won Chang ◽  
Won Yong Suh ◽  
...  

Sweet’s syndrome (SS) is an autoimmune-mediated acute febrile neutrophilic dermatosis with a number of possible etiologies, including infection, malignancy, and drug reactions. In contrast to its original description, it can rarely involve extracutaneous organs, including the central nervous system, cardiovascular system, lung, liver, gastrointestinal tract, spleen, and bone. To our knowledge, there have been only three cases of SS accompanied by acute kidney injury worldwide, and this is the first report in which the patient recovered completely from acute kidney injury as well as cutaneous lesions with early steroid administration. Here, we report a case of SS with acute kidney injury in a patient with myelodysplastic syndrome (MDS) whose skin lesions and renal function recovered fully with early diagnosis and steroid therapy along with a review of the relevant literature.


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