scholarly journals Diagnostic value of lumbar puncture among infants and children presenting with fever and convulsions

10.19082/2255 ◽  
2016 ◽  
Vol 8 (4) ◽  
pp. 2255-2262 ◽  
Author(s):  
Abdelrahim Abdrabou Sadek ◽  
Mostafa Ashry Mohamad ◽  
Safaa Hussin Ali ◽  
Ismail Abd Al-Aleem Hassan ◽  
Mohammad Fouad Hussein
1911 ◽  
Vol 57 (236) ◽  
pp. 1-18
Author(s):  
Hugh Morton

Within recent years it has become a recognised practice to perform lumbar puncture on cases suffering from cerebro-spinal disease; the practical value of the procedure is generally admitted as an aid to diagnosis; and in some diseases, such as tetanus and cerebro-spinal meningitis, the operation is resorted to for therapeutic purposes. It must, however, be admitted that it is only in such diseases of the cerebro-spinal system as are due to the presence of well-recognised organisms that the diagnostic value of lumbar puncture approaches scientific accuracy, in such diseases, for example, as tubercular meningitis, cerebro-spinal fever, pneumococcal meningitis, and sleeping-sickness. The value to be attached to an examination of the fluid for the syphilitic reaction is minimised when one considers that for this test the blood-serum is preferable.


Heart ◽  
1992 ◽  
Vol 68 (11) ◽  
pp. 488-492 ◽  
Author(s):  
P. J Scott ◽  
M. E Blackburn ◽  
G. A Wharton ◽  
N. Wilson ◽  
D. F Dickinson ◽  
...  

2012 ◽  
Vol 97 (Suppl 2) ◽  
pp. A445-A446
Author(s):  
Z. Barsoum ◽  
E. Kieran ◽  
J. Powell ◽  
N. Barrett ◽  
N. Connell ◽  
...  

2020 ◽  
pp. 1-4
Author(s):  
Doaa El Amrousy ◽  
Amr Zoair ◽  
Doaa El Amrousy ◽  
Elham Zahran ◽  
Hesham El-Serogy

Objectives: We aimed to investigate the levels and diagnostic value of plasma growth differentiation factor15 (GDF-15) in children with pulmonary hypertension associated with congenital heart disease (PH-CHD). Methods: One hundred infants and children with CHD were included in the study; 50 of them with PHCHD and another 50 patients with CHD only. Fifty healthy infants and children of matched age and sex were included as a control group. GDF-15 levels as well as echocardiographic examination were done for all included subjects. Cardiac catheterization was performed for patients only. Results: GDF-15 levels were significantly higher in patients with PH-CHD (0.62±0.2) nmol/ml compared to those with CHD only patients (0.21±0.06) nmol/ml and to control group (0.13±0.02) nmol/ml with P<0.001. GDF-15 levels were significantly elevated according to the severity of PH; (0.4±0.1) nmol/ml in mild PH vs (0.7±0.3) nmol/ml in moderate PH vs (1.1±0.1) nmol/ml in severe PH. At a cutoff value of ≥ 0.313 nmol/ml, the sensitivity of GDF-15 as a diagnostic biomarker in PH-CHD children was 95%, the specificity was 100%, positive predictive value (PPV) was 100%, and negative predictive value (NPV) was 95.2 %. Conclusion: GDF-15 is elevated in infants and children with PH-CHD and can be a promising diagnostic biomarker in these patients.


2018 ◽  
Vol 393 ◽  
pp. 72-79 ◽  
Author(s):  
Deby Mukendi ◽  
Jean-Roger Lilo Kalo ◽  
Tharcisse Kayembe ◽  
Pascal Lutumba ◽  
Barbara Barbé ◽  
...  

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