scholarly journals Transeosophageal echocardiography in neonates, infants and children: applicability and diagnostic value in everyday practice of a cardiothoracic unit

Heart ◽  
1992 ◽  
Vol 68 (11) ◽  
pp. 488-492 ◽  
Author(s):  
P. J Scott ◽  
M. E Blackburn ◽  
G. A Wharton ◽  
N. Wilson ◽  
D. F Dickinson ◽  
...  
10.19082/2255 ◽  
2016 ◽  
Vol 8 (4) ◽  
pp. 2255-2262 ◽  
Author(s):  
Abdelrahim Abdrabou Sadek ◽  
Mostafa Ashry Mohamad ◽  
Safaa Hussin Ali ◽  
Ismail Abd Al-Aleem Hassan ◽  
Mohammad Fouad Hussein

2020 ◽  
pp. 1-4
Author(s):  
Doaa El Amrousy ◽  
Amr Zoair ◽  
Doaa El Amrousy ◽  
Elham Zahran ◽  
Hesham El-Serogy

Objectives: We aimed to investigate the levels and diagnostic value of plasma growth differentiation factor15 (GDF-15) in children with pulmonary hypertension associated with congenital heart disease (PH-CHD). Methods: One hundred infants and children with CHD were included in the study; 50 of them with PHCHD and another 50 patients with CHD only. Fifty healthy infants and children of matched age and sex were included as a control group. GDF-15 levels as well as echocardiographic examination were done for all included subjects. Cardiac catheterization was performed for patients only. Results: GDF-15 levels were significantly higher in patients with PH-CHD (0.62±0.2) nmol/ml compared to those with CHD only patients (0.21±0.06) nmol/ml and to control group (0.13±0.02) nmol/ml with P<0.001. GDF-15 levels were significantly elevated according to the severity of PH; (0.4±0.1) nmol/ml in mild PH vs (0.7±0.3) nmol/ml in moderate PH vs (1.1±0.1) nmol/ml in severe PH. At a cutoff value of ≥ 0.313 nmol/ml, the sensitivity of GDF-15 as a diagnostic biomarker in PH-CHD children was 95%, the specificity was 100%, positive predictive value (PPV) was 100%, and negative predictive value (NPV) was 95.2 %. Conclusion: GDF-15 is elevated in infants and children with PH-CHD and can be a promising diagnostic biomarker in these patients.


PEDIATRICS ◽  
1965 ◽  
Vol 36 (5) ◽  
pp. 806-807
Author(s):  
M. EUGENE LAHEY ◽  
JOHN F. WILSON ◽  
DOUGLAS C. HEINER

In a paper dealing with Laparotomy for Rectal Bleeding (Pediatrics, 35:787, 1965) Shandling notes that no explanation was found at operation for enteric bleeding in 50 and 60% of infants and children. In view of this high percentage of "fruitlessly explored" patients, the author justifiably carefully analyzed the series of patients "to define indications for operation." Among the features studied were character of bleeding, relationship of bleeding to the stool, duration of symptoms, and the hemoglobin level—none of which were of particular diagnostic value.


Author(s):  
Gerald Fine ◽  
Azorides R. Morales

For years the separation of carcinoma and sarcoma and the subclassification of sarcomas has been based on the appearance of the tumor cells and their microscopic growth pattern and information derived from certain histochemical and special stains. Although this method of study has produced good agreement among pathologists in the separation of carcinoma from sarcoma, it has given less uniform results in the subclassification of sarcomas. There remain examples of neoplasms of different histogenesis, the classification of which is questionable because of similar cytologic and growth patterns at the light microscopic level; i.e. amelanotic melanoma versus carcinoma and occasionally sarcoma, sarcomas with an epithelial pattern of growth simulating carcinoma, histologically similar mesenchymal tumors of different histogenesis (histiocytoma versus rhabdomyosarcoma, lytic osteogenic sarcoma versus rhabdomyosarcoma), and myxomatous mesenchymal tumors of diverse histogenesis (myxoid rhabdo and liposarcomas, cardiac myxoma, myxoid neurofibroma, etc.)


2015 ◽  
Vol 25 (1) ◽  
pp. 15-23 ◽  
Author(s):  
Ryan W. McCreery ◽  
Elizabeth A. Walker ◽  
Meredith Spratford

The effectiveness of amplification for infants and children can be mediated by how much the child uses the device. Existing research suggests that establishing hearing aid use can be challenging. A wide range of factors can influence hearing aid use in children, including the child's age, degree of hearing loss, and socioeconomic status. Audiological interventions, including using validated prescriptive approaches and verification, performing on-going training and orientation, and communicating with caregivers about hearing aid use can also increase hearing aid use by infants and children. Case examples are used to highlight the factors that influence hearing aid use. Potential management strategies and future research needs are also discussed.


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