Caring for Nursing Staff Among Proficient First-Line Nurse Leaders

The aim of this qualitative study was to investigate proficient first-line nurse leaders’ caring for the nursing staff. The study was undertaken in Benner and Wrubel’s caring framework. Ten leaders were interviewed and data were analyzed following a hermeneutic approach. Caring for the nursing staff was imperative for the leaders; it was a moral agency linked to an ambition to perform high-quality care. The ambition could be assistance in bedside care, dialoguing with the staff, or planning for staff development. Further studies are needed and proficient nurse leaders need opportunities to discuss their ways of caring for the staff.

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First-line treatment of metastatic NSCLC (mNSCLC) patients without actionable mutations in U.S. community oncology clinical practice.

Journal of Clinical Oncology ◽

10.1200/jco.2016.34.7_suppl.307 ◽

2016 ◽

Vol 34 (7_suppl) ◽

pp. 307-307

Author(s):

Caroline McKay ◽

Ashwini Arunachalam ◽

Thomas A. Burke ◽

Xiting Cao ◽

Amy P Abernethy ◽

...

Keyword(s):

Maintenance Therapy ◽

Induction Therapy ◽

Quality Care ◽

Treatment Patterns ◽

Cancer Drug ◽

First Line ◽

High Quality ◽

High Quality Care ◽

Starting Point ◽

Anti Cancer

307 Background: Benchmarking high quality care requires defining optimally effective practice patterns. As first step, contemporary real-world practice must be detailed. The purpose of this study is to describe patient flow from diagnosis of mNSCLC to initiation of anti-cancer drug therapy in patients without known EGFR/ALK genomic tumor aberrations; the characteristics and first-line (1L) anti-cancer treatment of these patients, including induction and maintenance therapy. Methods: Retrospective database cohort study using data from an oncology EHR system, representing 17% of incident cancer cases from US community setting. Study population includes patients diagnosed with stage IV mNSCLC treated between 11/ 1/12 and 1/31/15 with follow-up to 7/31/15. Treatment patterns include regimen, number of doses, and time to regimen discontinuation. Data are analyzed descriptively, for overall cohort and by histology, with time to treatment discontinuation analyses using the Kaplan Meier method. Results: Of 4441 patients with mNSCLC, 88% had EGFR/ALK negative or unknown status. Of 79% who initiated 1L therapy, 69.5% (n = 2014) of patients (78.4% non-squamous, 21.7% squamous) were included. 55.1% were men; 89.8% were age 65+. 83.4% received induction therapy only; 16.6% received induction and maintenance therapy. 85% received a platinum combination as induction therapy; the majority either received a carboplatin doublet (53.5%) or carboplatin doublet in combination with targeted therapy (23.3%). 14.4% received a non-platinum based regimen. During induction therapy only, mean duration for the most common regimen category (platinum based combination) was 96.9 (IQR 43-129) for squamous and 79.45 (IQR 36-108) days for non-squamous patients. Of non-squamous patients who received induction followed by maintenance, mean duration of therapy was 103.9 (IQR 66-134) and 140.7 (IQR 45-208) days for induction and maintenance, respectively. Conclusions: Results describe treatment patterns in the US community 1L setting, prior to introduction of anti-PD1/PD-L1 inhibitors and new angiogenesis inhibitors. These form a starting point for benchmarking high quality care in mNSCLC.

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