The Role of Salivary and Serum Ca125 and Routine Blood Tests in Patients with Ovarian Malignancies

Abstract Objective The diagnosis of COVID-19 is based on the detection of SARS-CoV-2 in respiratory secretions, blood, or stool. Currently, reverse transcription polymerase chain reaction (RT-PCR) is the most commonly used method to test for SARS-CoV-2. Methods In this retrospective cohort analysis, we evaluated whether machine learning could exclude SARS-CoV-2 infection using routinely available laboratory values. A Random Forests algorithm with 1353 unique features was trained to predict the RT-PCR results. Results Out of 12,848 patients undergoing SARS-CoV-2 testing, routine blood tests were simultaneously performed in 1528 patients. The machine learning model could predict SARS-CoV-2 test results with an accuracy of 86% and an area under the receiver operating characteristic curve of 0.90. Conclusion Machine learning methods can reliably predict a negative SARS-CoV-2 RT-PCR test result using standard blood tests.

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236 Novel Guidelines to Avoid Routine Blood Tests After Robotic Assisted Radical Prostatectomy (RARP)

British Journal of Surgery ◽

10.1093/bjs/znab134.388 ◽

2021 ◽

Vol 108 (Supplement_2) ◽

Author(s):

A Nathan ◽

N Hanna ◽

A Rashid ◽

S Patel ◽

Y Phuah ◽

...

Keyword(s):

Blood Test ◽

Open Surgery ◽

Clinical Judgement ◽

Robotic Assisted ◽

Blood Tests ◽

Routine Blood ◽

Operative Complications ◽

Robotic Assisted Radical Prostatectomy ◽

The Uk ◽

Post Operative Complications

Abstract Introduction Patients undergoing RARP commonly require routine post-operative blood tests. This practice dates from an era of open surgery, with increased blood loss and complications. We aim to improve specificity of blood test requests with novel guidelines. Method 1039 consecutive RARP patients at two tertiary urology centres in the UK were audited. Novel guidelines constructed based on risk stratified evidence from the initial audit were used to prospectively audit 133 patients. Results 16% had clinical concerns post-operatively. 1% and 4% had an intra- and post-operative complication. Intra- or post-operative clinical judgement flagged post-operative complications in 99.9%. 80% had routine blood tests with no clinical concerns. 6% had delayed discharge due to delayed processing of blood tests. 0.9% received a peri-operative transfusion. Re-Audit Novel guidelines reduced the number of blood tests requested from 100% to 36%. Specificity in diagnosing a complication improved from 0% to 67%. Discharge delays reduced from 6% to 0% and no post-operative complications were missed (sensitivity 100%). Conclusions Routine blood tests, without an indication, did not flag any additional post-operative complications. Blood transfusion is rare for RARP. Novel guidelines to request post-operative blood tests will reduce costs and discharge delays whilst maintaining appropriate patient safety and care.

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Adaptive Neuro-Fuzzy Inference System (ANFIS) for Rapid Diagnosis of COVID-19 Cases Based on Routine Blood Tests

International Journal of Intelligent Engineering and Systems ◽

10.22266/ijies2021.0430.16 ◽

2021 ◽

Vol 14 (2) ◽

pp. 178-189

Author(s):

Mohanad Deif ◽

◽

Rania Hammam ◽

Ahmed Solyman ◽

◽

...

Keyword(s):

Fuzzy Inference System ◽

Fuzzy Inference ◽

Rapid Diagnosis ◽

Inference System ◽

Blood Tests ◽

Routine Blood ◽

Neuro Fuzzy

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A Proposed Set of New Guidelines for Routine Blood Tests during Isotretinoin Therapy for Acne vulgaris

Dermatology ◽

10.1159/000057887 ◽

2002 ◽

Vol 204 (3) ◽

pp. 232-235 ◽

Cited By ~ 33

Author(s):

Rachel S. Altman ◽

Lawrence J. Altman ◽

Jeffrey S. Altman

Keyword(s):

Acne Vulgaris ◽

Blood Tests ◽

Routine Blood ◽

New Guidelines ◽

Isotretinoin Therapy

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The Role of Stress in Interpreting the Dexamethasone Suppression Test

The Canadian Journal of Psychiatry ◽

10.1177/070674379203701009 ◽

1992 ◽

Vol 37 (10) ◽

pp. 724-727 ◽

Cited By ~ 1

Author(s):

Jane Blouin ◽

Eric Spindler ◽

Edgardo Perez ◽

Arthur Blouin ◽

Steven Hotz ◽

...

Keyword(s):

Environmental Stress ◽

Psychological Assessment ◽

Confounding Factor ◽

Dexamethasone Suppression Test ◽

Blood Tests ◽

Routine Administration ◽

Suppression Test ◽

Cortisol Suppression ◽

Dexamethasone Suppression

Stress has been implicated as a major confounding factor in the interpretation of Dexamethasone Suppression Test (DST) results. This study was designed to examine the effects of stress on DST results. Fifty patients with high levels of acute, chronic, and environmental stress participated in the study. Each patient was given a comprehensive psychiatric and psychological assessment, a routine administration of dexamethasone, and blood tests of cortisol values. The results indicate that the three measures of stress do not appear to affect levels of cortisol suppression, however, all three measures of stress predicted depression. As expected, DST cortisol levels were related to depression. Results are discussed in terms of their implications for understanding the associations among stress, depression and DST results.

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