scholarly journals DIAGNOSTIC OPPORTUNITIES OF NEUROOPHTHALMOLOGIC INSPECTION AT RS: ROLE OF AN OPTICAL COHERENT TOMOGRAPHY AND THE VISUAL CAUSED POTENTIALS IN EARLY DIAGNOSTICS OF MULTIPLE SCLEROSIS AND MONITORING OF A CONDITION OF THE VISUAL ANALYZER AT PATIENTS WITH VARIOUS OPTIONS OF MULTIPLE SCLEROSIS

2013 ◽  
Vol 12 (5) ◽  
pp. 119-125
Author(s):  
Ye. A. Andreyeva
Keyword(s):  
Multiple Sclerosis ◽  
Optic Nerve ◽  
Pathological Process ◽  
Visual Analyzer ◽  
Early Diagnostics ◽  
Optical Coherent Tomography ◽  
Macular Volume ◽  
P100 Component

Examination of 70 patients with different options of a course of multiple sclerosis is conducted. Reliable decrease in thickness of a layer of a neuroepithelium and macular volume of a retina at patients with various options of a course of the multiple sclerosis, more expressed is noted at primary progressing and secondary progressing current options, and the patients who have transferred an optical neuritis. The functional violations at the level of an optic nerve according to the visual caused potentials – increase in a latence and decrease in amplitude of the P100 component are revealed. Possibility of application of methods of an optical coherent tomography and the visual caused potentials for diagnostics and monitoring of pathological process is shown at multiple sclerosis.

scholarly journals ROLE OF THE COMPLEMENT AND CYTOKINES IN THE EARLYDIAGNOSIS OF MULTIPLE SCLEROSIS

2015 ◽  
Vol 7 (2) ◽  
pp. 40-44
Author(s):  
S V Lobzin ◽  
N B Serebryanaya ◽  
A M Ischenko ◽  
V I Golovkin ◽  
M V Fomintseva ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Cerebrospinal Fluid ◽  
Early Treatment ◽  
Subsequent Development ◽  
Pathological Process ◽  
Clinically Isolated Syndrome ◽  
Complement Proteins ◽  
Multiple Scle

In the article are presented the results of the study of blood and cerebrospinal fluid for cytokines and the complement proteins in 22 patients with clinically isolated syndrome in accordance with the subsequent development of the disease. It is find out the differences between the concentration of some complement proteins in patients with the developed during the observation the definite multiple scle- rosis in comparison with the patients with clinically isolated syndrome, and cytokine status. The de- termination of immunological predictors of multiple sclerosis development may help to understand the dynamics of pathological process and to start the early treatment.

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