Fabrication of Magnetically Driven Biopsy Mechanism Applicable to Capsule-Type Medical Device

2018 ◽  
Vol 30 (2) ◽  
pp. 292-299
Author(s):  
Toshiki Matsui ◽  
◽  
Satoshi Murata ◽  
Takashi Honda
Keyword(s):  
Magnetic Field ◽  
Small Intestine ◽  
Tissue Sample ◽  
Basic Structure ◽  
Rotating Magnetic Field ◽  
Intestinal Biopsy ◽  
Small Intestinal Biopsy ◽  
Operational Test ◽  
Actual Environment ◽  
Peristaltic Movement

This article proposes two kinds of magnetic rotary actuators applicable to a next-generation capsule endoscope that can conduct a small intestinal biopsy. One actuator is for an anchoring mechanism that can stop the capsule in a specific place against the peristaltic movement of the small intestine, and press a biopsy instrument on a lesion. The other actuator is for a biopsy mechanism that can project a circular blade while rotating, and obtain a tissue sample. Both actuators have the same basic structure, which is composed of a bolt with a permanent magnet and a nut, and can be driven by a rotating magnetic field. Because they are arranged orthogonally to each other in the capsule, they can be individually operated by the corresponding rotating magnetic field. Given the results of an operational test similar to an actual environment in a porcine small intestine, these actuators could successfully perform the desired operation.

scholarly journals Topography of Lectin Binding Sites in Celiac Sprue

1992 ◽  
Vol 6 (5) ◽  
pp. 271-276 ◽  
Author(s):  
Hugh J Freeman
Keyword(s):  
Small Intestine ◽  
Binding Sites ◽  
Lectin Binding ◽  
Membrane Surface ◽  
Celiac Sprue ◽  
Intestinal Biopsy ◽  
Small Intestinal Biopsy ◽  
Sequential Addition ◽  
Enterocytic Differentiation ◽  
Lectin Binding Sites

Lectins are ubiquitious, naturally occurring proteins largely derived from planes that are present in the human diet. They are released from food during mastication and digestion to remain biologically intact during passage through the small intestine. In this study, the topographic distribution of binding sites in the small intestine for six different lectins (derived from wheat germ, castor bean, gorse, horsegram, jackbean and peanut) were explored in 16 patients with celiac sprue a long with controls. For each lectin, the pattern of binding in the small intestinal biopsy specimens was distinct and specifically inhibited by a different carbohydrate residue. Lectin labelling patterns were different for both controls and celiac patients. in addition, the epithelial cell membrane surface and goblet cells exhibited a gradient of fluorescence intensity along the crypt-villus column. This gradient appeared to parallel the degree of enterocytic differentiation consistent with the concept that sequential addition of sugar residues to form completed oligosaccharide side chains occurs with enterocytic differentiation and maturation. These results also suggest that the process of epithelial cellular differentiation, although present in celiac enterocytes, is altered substantially.

THE LINEAR NON-IRON INDUCTOR WITH ROTATING MAGNETIC FIELD

2018 ◽  
Vol 2018 (49) ◽  
pp. 39-50
Author(s):  
О. Karlov ◽  
◽  
I. Kondratenko ◽  
R. Kryshchuk ◽  
A. Rashchepkin ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Rotating Magnetic Field

Effect of rotating magnetic field on the fading effect of Al–5Ti–1B in commercial pure Al

2014 ◽  
Vol 29 (15) ◽  
pp. 1656-1663 ◽  
Author(s):  
Hang Chen ◽  
Jinchuan Jie ◽  
Kateryna Svynarenko ◽  
Hongjun Ma ◽  
Tingju Li
Keyword(s):  
Magnetic Field ◽  
Rotating Magnetic Field ◽  
Fading Effect ◽  
Image Position

Abstract

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